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Article: A comparison of functional outcome in patients sustaining major trauma: A multicentre, prospective, international study
Title | A comparison of functional outcome in patients sustaining major trauma: A multicentre, prospective, international study |
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Authors | |
Issue Date | 2014 |
Citation | PLoS ONE, 2014, v. 9, n. 8, article no. e103396 How to Cite? |
Abstract | Objectives: To compare 6 month and 12 month health status and functional outcomes between regional major trauma registries in Hong Kong and Victoria, Australia. Summary Background Data: Multicentres from trauma registries in Hong Kong and the Victorian State Trauma Registry (VSTR). Methods: Multicentre, prospective cohort study. Major trauma patients and aged ≥18 years were included. The main outcome measures were Extended Glasgow Outcome Scale (GOSE) functional outcome and risk-adjusted Short-Form 12 (SF-12) health status at 6 and 12 months after injury. Results: 261 cases from Hong Kong and 1955 cases from VSTR were included. Adjusting for age, sex, ISS, comorbid status, injury mechanism and GCS group, the odds of a better functional outcome for Hong Kong patients relative to Victorian patients at six months was 0.88 (95% CI: 0.66, 1.17), and at 12 months was 0.83 (95% CI: 0.60, 1.12). Adjusting for age, gender, ISS, GCS, injury mechanism and comorbid status, Hong Kong patients demonstrated comparable mean PCS-12 scores at 6-months (adjusted mean difference: 1.2, 95% CI: -1.2, 3.6) and 12-months (adjusted mean difference: -0.4, 95% CI: -3.2, 2.4) compared to Victorian patients. Keeping age, gender, ISS, GCS, injury mechanism and comorbid status, there was no difference in the MCS-12 scores of Hong Kong patients compared to Victorian patients at 6-months (adjusted mean difference: 0.4, 95% CI: -2.1, 2.8) or 12-months (adjusted mean difference: 1.8, 95% CI: -0.8, 4.5). Conclusion: The unadjusted analyses showed better outcomes for Victorian cases compared to Hong Kong but after adjusting for key confounders, there was no difference in 6-month or 12-month functional outcomes between the jurisdictions. © 2014 Rainer et al. |
Persistent Identifier | http://hdl.handle.net/10722/292884 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Rainer, Timothy H. | - |
dc.contributor.author | Yeung, Hiu Hung | - |
dc.contributor.author | Gabbe, Belinda J. | - |
dc.contributor.author | Yuen, Kai Y. | - |
dc.contributor.author | Ho, Hiu F. | - |
dc.contributor.author | Kam, Chak W. | - |
dc.contributor.author | Chang, Annice | - |
dc.contributor.author | Poon, Wai S. | - |
dc.contributor.author | Cameron, Peter A. | - |
dc.contributor.author | Graham, Colin A. | - |
dc.date.accessioned | 2020-11-17T14:57:25Z | - |
dc.date.available | 2020-11-17T14:57:25Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | PLoS ONE, 2014, v. 9, n. 8, article no. e103396 | - |
dc.identifier.uri | http://hdl.handle.net/10722/292884 | - |
dc.description.abstract | Objectives: To compare 6 month and 12 month health status and functional outcomes between regional major trauma registries in Hong Kong and Victoria, Australia. Summary Background Data: Multicentres from trauma registries in Hong Kong and the Victorian State Trauma Registry (VSTR). Methods: Multicentre, prospective cohort study. Major trauma patients and aged ≥18 years were included. The main outcome measures were Extended Glasgow Outcome Scale (GOSE) functional outcome and risk-adjusted Short-Form 12 (SF-12) health status at 6 and 12 months after injury. Results: 261 cases from Hong Kong and 1955 cases from VSTR were included. Adjusting for age, sex, ISS, comorbid status, injury mechanism and GCS group, the odds of a better functional outcome for Hong Kong patients relative to Victorian patients at six months was 0.88 (95% CI: 0.66, 1.17), and at 12 months was 0.83 (95% CI: 0.60, 1.12). Adjusting for age, gender, ISS, GCS, injury mechanism and comorbid status, Hong Kong patients demonstrated comparable mean PCS-12 scores at 6-months (adjusted mean difference: 1.2, 95% CI: -1.2, 3.6) and 12-months (adjusted mean difference: -0.4, 95% CI: -3.2, 2.4) compared to Victorian patients. Keeping age, gender, ISS, GCS, injury mechanism and comorbid status, there was no difference in the MCS-12 scores of Hong Kong patients compared to Victorian patients at 6-months (adjusted mean difference: 0.4, 95% CI: -2.1, 2.8) or 12-months (adjusted mean difference: 1.8, 95% CI: -0.8, 4.5). Conclusion: The unadjusted analyses showed better outcomes for Victorian cases compared to Hong Kong but after adjusting for key confounders, there was no difference in 6-month or 12-month functional outcomes between the jurisdictions. © 2014 Rainer et al. | - |
dc.language | eng | - |
dc.relation.ispartof | PLoS ONE | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.title | A comparison of functional outcome in patients sustaining major trauma: A multicentre, prospective, international study | - |
dc.type | Article | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1371/journal.pone.0103396 | - |
dc.identifier.pmid | 25157522 | - |
dc.identifier.pmcid | PMC4144837 | - |
dc.identifier.scopus | eid_2-s2.0-84929290291 | - |
dc.identifier.volume | 9 | - |
dc.identifier.issue | 8 | - |
dc.identifier.spage | article no. e103396 | - |
dc.identifier.epage | article no. e103396 | - |
dc.identifier.eissn | 1932-6203 | - |
dc.identifier.isi | WOS:000341303200002 | - |
dc.identifier.issnl | 1932-6203 | - |