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Article: High degree of genetic differentiation in marine three-spined sticklebacks (Gasterosteus aculeatus)

TitleHigh degree of genetic differentiation in marine three-spined sticklebacks (Gasterosteus aculeatus)
Authors
Keywordsgenomic heterogeneity
marine
population differentiation
F ST
candidate gene
Issue Date2013
Citation
Molecular Ecology, 2013, v. 22, n. 18, p. 4811-4828 How to Cite?
AbstractPopulations of widespread marine organisms are typically characterized by a low degree of genetic differentiation in neutral genetic markers, but much less is known about differentiation in genes whose functional roles are associated with specific selection regimes. To uncover possible adaptive population divergence and heterogeneous genomic differentiation in marine three-spined sticklebacks (Gasterosteus aculeatus), we used a candidate gene-based genome-scan approach to analyse variability in 138 microsatellite loci located within/close to (<6 kb) functionally important genes in samples collected from ten geographic locations. The degree of genetic differentiation in markers classified as neutral or under balancing selection - as determined with several outlier detection methods - was low (FST = 0.033 or 0.011, respectively), whereas average FST for directionally selected markers was significantly higher (FST = 0.097). Clustering analyses provided support for genomic and geographic heterogeneity in selection: six genetic clusters were identified based on allele frequency differences in the directionally selected loci, whereas four were identified with the neutral loci. Allelic variation in several loci exhibited significant associations with environmental variables, supporting the conjecture that temperature and salinity, but not optic conditions, are important drivers of adaptive divergence among populations. In general, these results suggest that in spite of the high degree of physical connectivity and gene flow as inferred from neutral marker genes, marine stickleback populations are strongly genetically structured in loci associated with functionally relevant genes. © 2013 John Wiley & Sons Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/292771
ISSN
2023 Impact Factor: 4.5
2023 SCImago Journal Rankings: 1.705
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorDefaveri, Jacquelin-
dc.contributor.authorShikano, Takahito-
dc.contributor.authorShimada, Yukinori-
dc.contributor.authorMerilä, Juha-
dc.date.accessioned2020-11-17T14:57:11Z-
dc.date.available2020-11-17T14:57:11Z-
dc.date.issued2013-
dc.identifier.citationMolecular Ecology, 2013, v. 22, n. 18, p. 4811-4828-
dc.identifier.issn0962-1083-
dc.identifier.urihttp://hdl.handle.net/10722/292771-
dc.description.abstractPopulations of widespread marine organisms are typically characterized by a low degree of genetic differentiation in neutral genetic markers, but much less is known about differentiation in genes whose functional roles are associated with specific selection regimes. To uncover possible adaptive population divergence and heterogeneous genomic differentiation in marine three-spined sticklebacks (Gasterosteus aculeatus), we used a candidate gene-based genome-scan approach to analyse variability in 138 microsatellite loci located within/close to (<6 kb) functionally important genes in samples collected from ten geographic locations. The degree of genetic differentiation in markers classified as neutral or under balancing selection - as determined with several outlier detection methods - was low (FST = 0.033 or 0.011, respectively), whereas average FST for directionally selected markers was significantly higher (FST = 0.097). Clustering analyses provided support for genomic and geographic heterogeneity in selection: six genetic clusters were identified based on allele frequency differences in the directionally selected loci, whereas four were identified with the neutral loci. Allelic variation in several loci exhibited significant associations with environmental variables, supporting the conjecture that temperature and salinity, but not optic conditions, are important drivers of adaptive divergence among populations. In general, these results suggest that in spite of the high degree of physical connectivity and gene flow as inferred from neutral marker genes, marine stickleback populations are strongly genetically structured in loci associated with functionally relevant genes. © 2013 John Wiley & Sons Ltd.-
dc.languageeng-
dc.relation.ispartofMolecular Ecology-
dc.subjectgenomic heterogeneity-
dc.subjectmarine-
dc.subjectpopulation differentiation-
dc.subjectF ST-
dc.subjectcandidate gene-
dc.titleHigh degree of genetic differentiation in marine three-spined sticklebacks (Gasterosteus aculeatus)-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/mec.12430-
dc.identifier.scopuseid_2-s2.0-84883744195-
dc.identifier.volume22-
dc.identifier.issue18-
dc.identifier.spage4811-
dc.identifier.epage4828-
dc.identifier.eissn1365-294X-
dc.identifier.isiWOS:000324022600017-
dc.identifier.issnl0962-1083-

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