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- Publisher Website: 10.1038/hdy.2011.39
- Scopus: eid_2-s2.0-81255214943
- PMID: 21587305
- WOS: WOS:000297214900007
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Article: First-generation linkage map for the common frog Rana temporaria reveals sex-linkage group
Title | First-generation linkage map for the common frog Rana temporaria reveals sex-linkage group |
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Authors | |
Keywords | linkage map sex determination Rana temporaria quantitative trait loci microsatellite amphibian |
Issue Date | 2011 |
Citation | Heredity, 2011, v. 107, n. 6, p. 530-536 How to Cite? |
Abstract | The common frog (Rana temporaria) has become a model species in the fields of ecology and evolutionary biology. However, lack of genomic resources has been limiting utility of this species for detailed evolutionary genetic studies. Using a set of 107 informative microsatellite markers genotyped in a large full-sib family (800 F1 offspring), we created the first linkage map for this species. This partial map-distributed over 15 linkage groups-has a total length of 1698.8 cM. In line with the fact that males are the heterogametic sex in this species and a reduction of recombination is expected, we observed a lower recombination rate in the males (map length: 1371.5 cM) as compared with females (2089.8 cM). Furthermore, three loci previously documented to be sex-linked (that is, carrying male-specific alleles) in adults from the wild mapped to the same linkage group. The linkage map described in this study is one of the densest ones available for amphibians. The discovery of a sex linkage group in Rana temporaria, as well as other regions with strongly reduced male recombination rates, should help to uncover the genetic underpinnings of the sex-determination system in this species. As the number of linkage groups found (n=15) is quite close to the actual number of chromosomes (n=13), the map should provide a useful resource for further evolutionary, ecological and conservation genetic work in this and other closely related species. © 2011 Macmillan Publishers Limited All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/292670 |
ISSN | 2023 Impact Factor: 3.1 2023 SCImago Journal Rankings: 1.039 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Cano, J. M. | - |
dc.contributor.author | Li, M. H. | - |
dc.contributor.author | Laurila, A. | - |
dc.contributor.author | Vilkki, J. | - |
dc.contributor.author | Merilä, J. | - |
dc.date.accessioned | 2020-11-17T14:56:58Z | - |
dc.date.available | 2020-11-17T14:56:58Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | Heredity, 2011, v. 107, n. 6, p. 530-536 | - |
dc.identifier.issn | 0018-067X | - |
dc.identifier.uri | http://hdl.handle.net/10722/292670 | - |
dc.description.abstract | The common frog (Rana temporaria) has become a model species in the fields of ecology and evolutionary biology. However, lack of genomic resources has been limiting utility of this species for detailed evolutionary genetic studies. Using a set of 107 informative microsatellite markers genotyped in a large full-sib family (800 F1 offspring), we created the first linkage map for this species. This partial map-distributed over 15 linkage groups-has a total length of 1698.8 cM. In line with the fact that males are the heterogametic sex in this species and a reduction of recombination is expected, we observed a lower recombination rate in the males (map length: 1371.5 cM) as compared with females (2089.8 cM). Furthermore, three loci previously documented to be sex-linked (that is, carrying male-specific alleles) in adults from the wild mapped to the same linkage group. The linkage map described in this study is one of the densest ones available for amphibians. The discovery of a sex linkage group in Rana temporaria, as well as other regions with strongly reduced male recombination rates, should help to uncover the genetic underpinnings of the sex-determination system in this species. As the number of linkage groups found (n=15) is quite close to the actual number of chromosomes (n=13), the map should provide a useful resource for further evolutionary, ecological and conservation genetic work in this and other closely related species. © 2011 Macmillan Publishers Limited All rights reserved. | - |
dc.language | eng | - |
dc.relation.ispartof | Heredity | - |
dc.subject | linkage map | - |
dc.subject | sex determination | - |
dc.subject | Rana temporaria | - |
dc.subject | quantitative trait loci | - |
dc.subject | microsatellite | - |
dc.subject | amphibian | - |
dc.title | First-generation linkage map for the common frog Rana temporaria reveals sex-linkage group | - |
dc.type | Article | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1038/hdy.2011.39 | - |
dc.identifier.pmid | 21587305 | - |
dc.identifier.pmcid | PMC3242625 | - |
dc.identifier.scopus | eid_2-s2.0-81255214943 | - |
dc.identifier.volume | 107 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 530 | - |
dc.identifier.epage | 536 | - |
dc.identifier.eissn | 1365-2540 | - |
dc.identifier.isi | WOS:000297214900007 | - |
dc.identifier.issnl | 0018-067X | - |