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- Publisher Website: 10.1016/0952-7915(93)90042-Q
- Scopus: eid_2-s2.0-0027328420
- PMID: 8105804
- WOS: WOS:A1993LU97500018
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Article: Genetically modified animals and immunodeficiency
Title | Genetically modified animals and immunodeficiency |
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Authors | |
Issue Date | 1993 |
Citation | Current Opinion in Immunology, 1993, v. 5, n. 4, p. 585-594 How to Cite? |
Abstract | Mouse strains with defined genetic defects engineered by the method of targeted gene disruption and homologous recombination have furthered our understanding of immune functions at the single gene level. More importantly, these mutant 'gene knockout' mice are powerful in vivo tools to dissect the complex mechanisms of lymphocyte development and function, complementing our broadening knowledge of congenital and acquired human immunodeficiencies. © 1993. |
Persistent Identifier | http://hdl.handle.net/10722/292413 |
ISSN | 2023 Impact Factor: 6.6 2023 SCImago Journal Rankings: 2.841 |
ISI Accession Number ID | |
Errata |
DC Field | Value | Language |
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dc.contributor.author | Yeung, Rae S.M. | - |
dc.contributor.author | Penninger, Josef | - |
dc.contributor.author | Mak, Tak W. | - |
dc.date.accessioned | 2020-11-17T14:56:26Z | - |
dc.date.available | 2020-11-17T14:56:26Z | - |
dc.date.issued | 1993 | - |
dc.identifier.citation | Current Opinion in Immunology, 1993, v. 5, n. 4, p. 585-594 | - |
dc.identifier.issn | 0952-7915 | - |
dc.identifier.uri | http://hdl.handle.net/10722/292413 | - |
dc.description.abstract | Mouse strains with defined genetic defects engineered by the method of targeted gene disruption and homologous recombination have furthered our understanding of immune functions at the single gene level. More importantly, these mutant 'gene knockout' mice are powerful in vivo tools to dissect the complex mechanisms of lymphocyte development and function, complementing our broadening knowledge of congenital and acquired human immunodeficiencies. © 1993. | - |
dc.language | eng | - |
dc.relation.ispartof | Current Opinion in Immunology | - |
dc.title | Genetically modified animals and immunodeficiency | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/0952-7915(93)90042-Q | - |
dc.identifier.pmid | 8105804 | - |
dc.identifier.scopus | eid_2-s2.0-0027328420 | - |
dc.identifier.volume | 5 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 585 | - |
dc.identifier.epage | 594 | - |
dc.identifier.isi | WOS:A1993LU97500018 | - |
dc.relation.erratum | doi:10.1016/0952-7915(93)90115-9 | - |
dc.relation.erratum | eid:eid_2-s2.0-0027443938 | - |
dc.identifier.issnl | 0952-7915 | - |