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Article: Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer

TitleReconstitution of an active surface T3/T-cell antigen receptor by DNA transfer
Authors
Issue Date1985
Citation
Nature, 1985, v. 316, n. 6029, p. 606-609 How to Cite?
AbstractWe have introduced a full-length complementary DNA of the T-cell antigen receptor β-chain into a mutant human T-cell line that lacked a complete β-chain messenger RNA, had a diminished level of α-chain transcript and did not express surface T3- or antigen receptor. Expression of the transfected β-chain led to a normal level of α-chain transcript and a structurally and functionally active T3 T-cell antigen receptor complex on the cell surface. © 1985 Nature Publishing Group.
Persistent Identifierhttp://hdl.handle.net/10722/292296
ISSN
2023 Impact Factor: 50.5
2023 SCImago Journal Rankings: 18.509
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorOhashi, Pamela S.-
dc.contributor.authorMak, Tak W.-
dc.contributor.authorVan Den Elsen, Peter-
dc.contributor.authorYanagi, Yusuke-
dc.contributor.authorYoshikai, Yasunobu-
dc.contributor.authorCalman, Andrew F.-
dc.contributor.authorTerhorst, Cox-
dc.contributor.authorStobo, John D.-
dc.contributor.authorWeiss, Arthur-
dc.date.accessioned2020-11-17T14:56:10Z-
dc.date.available2020-11-17T14:56:10Z-
dc.date.issued1985-
dc.identifier.citationNature, 1985, v. 316, n. 6029, p. 606-609-
dc.identifier.issn0028-0836-
dc.identifier.urihttp://hdl.handle.net/10722/292296-
dc.description.abstractWe have introduced a full-length complementary DNA of the T-cell antigen receptor β-chain into a mutant human T-cell line that lacked a complete β-chain messenger RNA, had a diminished level of α-chain transcript and did not express surface T3- or antigen receptor. Expression of the transfected β-chain led to a normal level of α-chain transcript and a structurally and functionally active T3 T-cell antigen receptor complex on the cell surface. © 1985 Nature Publishing Group.-
dc.languageeng-
dc.relation.ispartofNature-
dc.titleReconstitution of an active surface T3/T-cell antigen receptor by DNA transfer-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/316606a0-
dc.identifier.pmid4033759-
dc.identifier.scopuseid_2-s2.0-0022384633-
dc.identifier.volume316-
dc.identifier.issue6029-
dc.identifier.spage606-
dc.identifier.epage609-
dc.identifier.isiWOS:A1985ANX3500041-
dc.identifier.issnl0028-0836-

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