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- Publisher Website: 10.1016/j.ccell.2016.03.020
- Scopus: eid_2-s2.0-84962633169
- PMID: 27070694
- WOS: WOS:000373854600004
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Article: Targeting PI3K Signaling in Cancer: A Cautionary Tale of Two AKTs
| Title | Targeting PI3K Signaling in Cancer: A Cautionary Tale of Two AKTs |
|---|---|
| Authors | |
| Issue Date | 2016 |
| Citation | Cancer Cell, 2016, v. 29, n. 4, p. 429-431 How to Cite? |
| Abstract | © 2016 Elsevier Inc. AKT inhibitors represent promising therapeutics for cancers with PI3K-AKT pathway hyperactivation. In this issue of Cancer Cell, Wang et al. (2016) report the unexpected finding that ablation of AKT signaling in hepatocytes leads to hepatocellular carcinoma and enhances the incidence of lung metastases in a toxin-induced liver cancer model. |
| Persistent Identifier | http://hdl.handle.net/10722/292069 |
| ISSN | 2023 Impact Factor: 48.8 2023 SCImago Journal Rankings: 17.507 |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Fortin, Jérôme | - |
| dc.contributor.author | Mak, Tak W. | - |
| dc.date.accessioned | 2020-11-17T14:55:42Z | - |
| dc.date.available | 2020-11-17T14:55:42Z | - |
| dc.date.issued | 2016 | - |
| dc.identifier.citation | Cancer Cell, 2016, v. 29, n. 4, p. 429-431 | - |
| dc.identifier.issn | 1535-6108 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/292069 | - |
| dc.description.abstract | © 2016 Elsevier Inc. AKT inhibitors represent promising therapeutics for cancers with PI3K-AKT pathway hyperactivation. In this issue of Cancer Cell, Wang et al. (2016) report the unexpected finding that ablation of AKT signaling in hepatocytes leads to hepatocellular carcinoma and enhances the incidence of lung metastases in a toxin-induced liver cancer model. | - |
| dc.language | eng | - |
| dc.relation.ispartof | Cancer Cell | - |
| dc.title | Targeting PI3K Signaling in Cancer: A Cautionary Tale of Two AKTs | - |
| dc.type | Article | - |
| dc.description.nature | link_to_OA_fulltext | - |
| dc.identifier.doi | 10.1016/j.ccell.2016.03.020 | - |
| dc.identifier.pmid | 27070694 | - |
| dc.identifier.scopus | eid_2-s2.0-84962633169 | - |
| dc.identifier.volume | 29 | - |
| dc.identifier.issue | 4 | - |
| dc.identifier.spage | 429 | - |
| dc.identifier.epage | 431 | - |
| dc.identifier.eissn | 1878-3686 | - |
| dc.identifier.isi | WOS:000373854600004 | - |
| dc.identifier.issnl | 1535-6108 | - |