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Article: Rhh: An R extension for estimating multilocus heterozygosity and heterozygosity-heterozygosity correlation

TitleRhh: An R extension for estimating multilocus heterozygosity and heterozygosity-heterozygosity correlation
Authors
KeywordsHeterozygosity-heterozygosity correlation
Standardized heterozygosity
Multilocus heterozygosity
Homozygosity
Inbreeding
Internal relatedness
Issue Date2010
Citation
Molecular Ecology Resources, 2010, v. 10, n. 4, p. 720-722 How to Cite?
AbstractIndividual multilocus heterozygosity estimates based on a limited number of loci are expected to correlate only weakly with the inbreeding level of an individual. Before using multilocus heterozygosity estimates in studies of inbreeding, their ability to capture information on inbreeding in the given setting should be tested. A convenient method for this is to compute the heterozygosity-heterozygosity correlation, i.e. the mean correlation between multilocus heterozygosity estimates calculated from random samples of loci, which should be positive if multilocus heterozygosity carries a signature of inbreeding. Rhh is an extension package for the statistical software r that estimates this correlation and calculates three measures of individual multilocus heterozygosity: homozygosity by loci, internal relatedness and standardized heterozygosity. The extension package is available through the CRAN (http://cran.r-project.org) and has a homepage at http://www.helsinki.fi/biosci/egru/research/software. © 2010 Blackwell Publishing Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/291976
ISSN
2023 Impact Factor: 5.5
2023 SCImago Journal Rankings: 2.465
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorAlho, Jussi S.-
dc.contributor.authorVälimäki, Kaisa-
dc.contributor.authorMerilä, Juha-
dc.date.accessioned2020-11-17T14:55:30Z-
dc.date.available2020-11-17T14:55:30Z-
dc.date.issued2010-
dc.identifier.citationMolecular Ecology Resources, 2010, v. 10, n. 4, p. 720-722-
dc.identifier.issn1755-098X-
dc.identifier.urihttp://hdl.handle.net/10722/291976-
dc.description.abstractIndividual multilocus heterozygosity estimates based on a limited number of loci are expected to correlate only weakly with the inbreeding level of an individual. Before using multilocus heterozygosity estimates in studies of inbreeding, their ability to capture information on inbreeding in the given setting should be tested. A convenient method for this is to compute the heterozygosity-heterozygosity correlation, i.e. the mean correlation between multilocus heterozygosity estimates calculated from random samples of loci, which should be positive if multilocus heterozygosity carries a signature of inbreeding. Rhh is an extension package for the statistical software r that estimates this correlation and calculates three measures of individual multilocus heterozygosity: homozygosity by loci, internal relatedness and standardized heterozygosity. The extension package is available through the CRAN (http://cran.r-project.org) and has a homepage at http://www.helsinki.fi/biosci/egru/research/software. © 2010 Blackwell Publishing Ltd.-
dc.languageeng-
dc.relation.ispartofMolecular Ecology Resources-
dc.subjectHeterozygosity-heterozygosity correlation-
dc.subjectStandardized heterozygosity-
dc.subjectMultilocus heterozygosity-
dc.subjectHomozygosity-
dc.subjectInbreeding-
dc.subjectInternal relatedness-
dc.titleRhh: An R extension for estimating multilocus heterozygosity and heterozygosity-heterozygosity correlation-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1755-0998.2010.02830.x-
dc.identifier.scopuseid_2-s2.0-77954732452-
dc.identifier.volume10-
dc.identifier.issue4-
dc.identifier.spage720-
dc.identifier.epage722-
dc.identifier.eissn1755-0998-
dc.identifier.isiWOS:000278676300015-
dc.identifier.issnl1755-098X-

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