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Article: Grüneisen-relaxation photoacoustic microscopy at 1.7  µm and its application in lipid imaging

TitleGrüneisen-relaxation photoacoustic microscopy at 1.7  µm and its application in lipid imaging
Authors
KeywordsAdipose tissue
Atherosclerotic plaque
Contrast Enhancement
High-resolution imaging
Image contrasts
Issue Date2020
PublisherOptical Society of America. The Journal's web site is located at http://www.opticsinfobase.org/current.cfm?journal=3
Citation
Optics Letters, 2020, v. 45 n. 12, p. 3268-3271 How to Cite?
AbstractWe report the first, to the best of our knowledge, demonstration of Grüneisen relaxation photoacoustic microscopy (GR-PAM) of lipid-rich tissue imaging at the 1.7 µm band, implemented with a high-energy thulium-doped fiber laser and a fiber-based delay line. GR-PAM enhances the image contrast by intensifying the region of strong absorbers and suppressing out-of-focus signals. Using GR-PAM to image swine-adipose tissue at 1725 nm, an 8.26-fold contrast enhancement is achieved in comparison to conventional PAM. GR-PAM at the 1.7 µm band is expected to be a useful tool for label-free high-resolution imaging of lipid-rich tissue, such as atherosclerotic plaque and nerves.
Persistent Identifierhttp://hdl.handle.net/10722/290172
ISSN
2023 Impact Factor: 3.1
2023 SCImago Journal Rankings: 1.040
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorShi, J-
dc.contributor.authorLi, C-
dc.contributor.authorMAO, H-
dc.contributor.authorRen, Y-
dc.contributor.authorLuo, ZC-
dc.contributor.authorRosenthal, A-
dc.contributor.authorWong, KKY-
dc.date.accessioned2020-10-22T08:23:04Z-
dc.date.available2020-10-22T08:23:04Z-
dc.date.issued2020-
dc.identifier.citationOptics Letters, 2020, v. 45 n. 12, p. 3268-3271-
dc.identifier.issn0146-9592-
dc.identifier.urihttp://hdl.handle.net/10722/290172-
dc.description.abstractWe report the first, to the best of our knowledge, demonstration of Grüneisen relaxation photoacoustic microscopy (GR-PAM) of lipid-rich tissue imaging at the 1.7 µm band, implemented with a high-energy thulium-doped fiber laser and a fiber-based delay line. GR-PAM enhances the image contrast by intensifying the region of strong absorbers and suppressing out-of-focus signals. Using GR-PAM to image swine-adipose tissue at 1725 nm, an 8.26-fold contrast enhancement is achieved in comparison to conventional PAM. GR-PAM at the 1.7 µm band is expected to be a useful tool for label-free high-resolution imaging of lipid-rich tissue, such as atherosclerotic plaque and nerves.-
dc.languageeng-
dc.publisherOptical Society of America. The Journal's web site is located at http://www.opticsinfobase.org/current.cfm?journal=3-
dc.relation.ispartofOptics Letters-
dc.rightsOptics Letters. Copyright © Optical Society of America.-
dc.rights© XXXX [year] Optical Society of America]. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modifications of the content of this paper are prohibited.-
dc.subjectAdipose tissue-
dc.subjectAtherosclerotic plaque-
dc.subjectContrast Enhancement-
dc.subjectHigh-resolution imaging-
dc.subjectImage contrasts-
dc.titleGrüneisen-relaxation photoacoustic microscopy at 1.7  µm and its application in lipid imaging-
dc.typeArticle-
dc.identifier.emailLi, C: canl@hku.hk-
dc.identifier.emailRen, Y: yxren@hku.hk-
dc.identifier.emailWong, KKY: kywong@eee.hku.hk-
dc.identifier.authorityLi, C=rp02706-
dc.identifier.authorityWong, KKY=rp00189-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1364/OL.393780-
dc.identifier.pmid32538959-
dc.identifier.scopuseid_2-s2.0-85086619657-
dc.identifier.hkuros316953-
dc.identifier.volume45-
dc.identifier.issue12-
dc.identifier.spage3268-
dc.identifier.epage3271-
dc.identifier.isiWOS:000541729300023-
dc.publisher.placeUnited States-
dc.identifier.issnl0146-9592-

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