File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: A multidimensional risk factor model for suicide attempts in later life

TitleA multidimensional risk factor model for suicide attempts in later life
Authors
KeywordsChronic medical illness
Cognitive function
Suicide
Later life
Issue Date2014
PublisherDove Medical Press Ltd. The Journal's web site is located at http://www.dovepress.com/articles.php?journal_id=3
Citation
Neuropsychiatric Disease and Treatment, 2014, v. 10, p. 1807-1817 How to Cite?
AbstractBackground: Elderly suicide is a public health problem worldwide, and the risk factors are multidimensional. Chronic mental health problems, personality traits, stressful life events, comorbid medical conditions, social isolation, unemployment, and poverty are associated with higher risk for suicide in later life. There was a relative paucity of data on the neurobiological markers of elderly suicide. Objective: This study examines the conjoint roles of cerebrovascular risk factors (CVRFs) and other established biopsychosocial risk factors in older adults who had made a recent suicide attempt. Design: A cross-sectional, case-controlled study. Setting: A tertiary care setting in a public sector and a community setting. Subjects and methods: Cases (N=77) were nondemented Chinese adults aged ≥65 years, enrolled in a regional psychogeriatric service following a suicide attempt; comparison subjects (N=99) were community-dwelling nondemented older adults with no lifetime history of suicide. Measures of sociodemographic profile, life events, suicidal behavior, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) Axis I psychopathology, personality traits, functional status, physical health, CVRFs, and executive cognitive functions were administered. Results: Weighted sum of CVRF score was significantly higher in older women who had made a recent suicide attempt (mean: 10.56; standard deviation [SD]: 5.46) than comparison subjects (mean: 7.24; SD: 4.04) (t=3.52, P=0.001; df=99). Logistic regression showed that CVRF score (Exp[B]: 1.289, P=0.033), DSM-IV depressive disorders (current) (Exp[B]: 348, P<0.001), number of life events in the past 12 weeks (Exp[B]: 10.4; P<0.001), and being married (Exp[B]: 12.2, P<0.048) significantly increased odds for suicide attempt status in older women (Nagelkerke R2: 0.844). Association of CVRF score and suicide attempt status was not observed in older men for whom number of life events in the past 12 weeks (Exp[B]: 9.164; P<0.001), higher neuroticism (Exp[B]: 1.028; P=0.048), and impaired performance on a Modified Card Sorting Test (Exp[B]: 0.646; P=0.032) significantly increased odds for suicide attempt status in a logistic regression model (Nagelkerke R2: 0.611). Conclusion: Risk factors for cerebrovascular diseases may be associated with higher risk for attempted suicide in older women, but not in older men. Older men and women have distinct risk factor profiles that may inform targeted intervention and prevention strategies.
Persistent Identifierhttp://hdl.handle.net/10722/289156
ISSN
2020 Impact Factor: 2.57
2020 SCImago Journal Rankings: 0.819
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, SMS-
dc.contributor.authorChiu, FKH-
dc.contributor.authorLam, CWL-
dc.contributor.authorWong, SMC-
dc.contributor.authorConwell, Y-
dc.date.accessioned2020-10-22T08:08:37Z-
dc.date.available2020-10-22T08:08:37Z-
dc.date.issued2014-
dc.identifier.citationNeuropsychiatric Disease and Treatment, 2014, v. 10, p. 1807-1817-
dc.identifier.issn1176-6328-
dc.identifier.urihttp://hdl.handle.net/10722/289156-
dc.description.abstractBackground: Elderly suicide is a public health problem worldwide, and the risk factors are multidimensional. Chronic mental health problems, personality traits, stressful life events, comorbid medical conditions, social isolation, unemployment, and poverty are associated with higher risk for suicide in later life. There was a relative paucity of data on the neurobiological markers of elderly suicide. Objective: This study examines the conjoint roles of cerebrovascular risk factors (CVRFs) and other established biopsychosocial risk factors in older adults who had made a recent suicide attempt. Design: A cross-sectional, case-controlled study. Setting: A tertiary care setting in a public sector and a community setting. Subjects and methods: Cases (N=77) were nondemented Chinese adults aged ≥65 years, enrolled in a regional psychogeriatric service following a suicide attempt; comparison subjects (N=99) were community-dwelling nondemented older adults with no lifetime history of suicide. Measures of sociodemographic profile, life events, suicidal behavior, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) Axis I psychopathology, personality traits, functional status, physical health, CVRFs, and executive cognitive functions were administered. Results: Weighted sum of CVRF score was significantly higher in older women who had made a recent suicide attempt (mean: 10.56; standard deviation [SD]: 5.46) than comparison subjects (mean: 7.24; SD: 4.04) (t=3.52, P=0.001; df=99). Logistic regression showed that CVRF score (Exp[B]: 1.289, P=0.033), DSM-IV depressive disorders (current) (Exp[B]: 348, P<0.001), number of life events in the past 12 weeks (Exp[B]: 10.4; P<0.001), and being married (Exp[B]: 12.2, P<0.048) significantly increased odds for suicide attempt status in older women (Nagelkerke R2: 0.844). Association of CVRF score and suicide attempt status was not observed in older men for whom number of life events in the past 12 weeks (Exp[B]: 9.164; P<0.001), higher neuroticism (Exp[B]: 1.028; P=0.048), and impaired performance on a Modified Card Sorting Test (Exp[B]: 0.646; P=0.032) significantly increased odds for suicide attempt status in a logistic regression model (Nagelkerke R2: 0.611). Conclusion: Risk factors for cerebrovascular diseases may be associated with higher risk for attempted suicide in older women, but not in older men. Older men and women have distinct risk factor profiles that may inform targeted intervention and prevention strategies.-
dc.languageeng-
dc.publisherDove Medical Press Ltd. The Journal's web site is located at http://www.dovepress.com/articles.php?journal_id=3-
dc.relation.ispartofNeuropsychiatric Disease and Treatment-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectChronic medical illness-
dc.subjectCognitive function-
dc.subjectSuicide-
dc.subjectLater life-
dc.titleA multidimensional risk factor model for suicide attempts in later life-
dc.typeArticle-
dc.identifier.emailWong, SMC: wongcsm@hku.hk-
dc.identifier.authorityWong, SMC=rp02625-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.2147/NDT.S70011-
dc.identifier.pmid25258538-
dc.identifier.pmcidPMC4174030-
dc.identifier.scopuseid_2-s2.0-84907215527-
dc.identifier.hkuros316958-
dc.identifier.volume10-
dc.identifier.spage1807-
dc.identifier.epage1817-
dc.identifier.isiWOS:000341749500001-
dc.publisher.placeNew Zealand-
dc.identifier.issnl1176-6328-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats