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- Publisher Website: 10.1016/j.colsurfb.2020.110781
- Scopus: eid_2-s2.0-85077652024
- PMID: 31935632
- WOS: WOS:000527305100074
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Article: Zn2+-assisted photothermal therapy for rapid bacteria-killing using biodegradable humic acid encapsulated MOFs
Title | Zn2+-assisted photothermal therapy for rapid bacteria-killing using biodegradable humic acid encapsulated MOFs |
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Authors | |
Keywords | Humic acid MOF Photothermal Controlled release Antibacterial |
Issue Date | 2020 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/colsurfb |
Citation | Colloids and Surfaces B: Biointerfaces, 2020, v. 188, p. article no. 110781 How to Cite? |
Abstract | Bacterial infection is seriously threatening human health all over the world, especially with the emergence of increasing drug-fast bacteria. It is urgent to develop a drug-free strategy to kill bacteria rapidly and efficiently. In this work, humic acid (HuA) encapsulated zeolitic imidazole framework-8 (ZIF-8) (HuA@ZIF-8) nanocomposites are synthesized by the in-situ growth of ZIF-8 on the surface of polyvinylpyrrolidone (PVP)-modified HuA. The synthesized nanocomposites possesses good photothermal effects, i.e., the temperature increased to 59.4 °C under the particle concentration of 1000 μg/mL with 10 min NIR irradiation. In addition, NIR irradiation can also control the release of Zn2+ from the composites. The good photothermal effects originate from HuA that can effectively absorb NIR light. The controlled release of Zn2+ is ascribed to the induced-dissociation of ZIF-8 under NIR light irradiation. The synergistic action of photothermal therapy and release of zinc ions contributes to the excellent antibacterial efficiency of HuA@ZIF-8 within a short time, i.e. 99.59 % and 99.37 % against Staphylococcus aureus and Escherichia coli with 20 min NIR irradiation, respectively. This work provides a promising strategy to develop a light-responsive platform with good biodegradability and low cost for rapid and effective sterilization. |
Persistent Identifier | http://hdl.handle.net/10722/289135 |
ISSN | 2023 Impact Factor: 5.4 2023 SCImago Journal Rankings: 0.910 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | LIU, Z | - |
dc.contributor.author | TAN, L | - |
dc.contributor.author | LIU, X | - |
dc.contributor.author | LIANG, Y | - |
dc.contributor.author | ZHENG, Y | - |
dc.contributor.author | Yeung, KWK | - |
dc.contributor.author | CUI, Z | - |
dc.contributor.author | ZHU, S | - |
dc.contributor.author | LI, Z | - |
dc.contributor.author | WU, S | - |
dc.date.accessioned | 2020-10-22T08:08:18Z | - |
dc.date.available | 2020-10-22T08:08:18Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Colloids and Surfaces B: Biointerfaces, 2020, v. 188, p. article no. 110781 | - |
dc.identifier.issn | 0927-7765 | - |
dc.identifier.uri | http://hdl.handle.net/10722/289135 | - |
dc.description.abstract | Bacterial infection is seriously threatening human health all over the world, especially with the emergence of increasing drug-fast bacteria. It is urgent to develop a drug-free strategy to kill bacteria rapidly and efficiently. In this work, humic acid (HuA) encapsulated zeolitic imidazole framework-8 (ZIF-8) (HuA@ZIF-8) nanocomposites are synthesized by the in-situ growth of ZIF-8 on the surface of polyvinylpyrrolidone (PVP)-modified HuA. The synthesized nanocomposites possesses good photothermal effects, i.e., the temperature increased to 59.4 °C under the particle concentration of 1000 μg/mL with 10 min NIR irradiation. In addition, NIR irradiation can also control the release of Zn2+ from the composites. The good photothermal effects originate from HuA that can effectively absorb NIR light. The controlled release of Zn2+ is ascribed to the induced-dissociation of ZIF-8 under NIR light irradiation. The synergistic action of photothermal therapy and release of zinc ions contributes to the excellent antibacterial efficiency of HuA@ZIF-8 within a short time, i.e. 99.59 % and 99.37 % against Staphylococcus aureus and Escherichia coli with 20 min NIR irradiation, respectively. This work provides a promising strategy to develop a light-responsive platform with good biodegradability and low cost for rapid and effective sterilization. | - |
dc.language | eng | - |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/colsurfb | - |
dc.relation.ispartof | Colloids and Surfaces B: Biointerfaces | - |
dc.subject | Humic acid | - |
dc.subject | MOF | - |
dc.subject | Photothermal | - |
dc.subject | Controlled release | - |
dc.subject | Antibacterial | - |
dc.title | Zn2+-assisted photothermal therapy for rapid bacteria-killing using biodegradable humic acid encapsulated MOFs | - |
dc.type | Article | - |
dc.identifier.email | Yeung, KWK: wkkyeung@hku.hk | - |
dc.identifier.authority | Yeung, KWK=rp00309 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.colsurfb.2020.110781 | - |
dc.identifier.pmid | 31935632 | - |
dc.identifier.scopus | eid_2-s2.0-85077652024 | - |
dc.identifier.hkuros | 317559 | - |
dc.identifier.volume | 188 | - |
dc.identifier.spage | article no. 110781 | - |
dc.identifier.epage | article no. 110781 | - |
dc.identifier.isi | WOS:000527305100074 | - |
dc.publisher.place | Netherlands | - |
dc.identifier.issnl | 0927-7765 | - |