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- Publisher Website: 10.1177/0022034520906384
- Scopus: eid_2-s2.0-85081921508
- PMID: 32142400
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Article: Topical fluoride to prevent root caries: systematic review with network meta-analysis
Title | Topical fluoride to prevent root caries: systematic review with network meta-analysis |
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Authors | |
Keywords | dental caries prevention systematic review fluorides aged |
Issue Date | 2020 |
Publisher | Sage Publications, Inc. The Journal's web site is located at http://jdr.sagepub.com/ |
Citation | Journal of Dental Research, 2020, v. 99 n. 5, p. 506-513 How to Cite? |
Abstract | The aim of this systematic review and network meta-analysis was to summarize the direct and indirect clinical evidence on the effectiveness of professionally applied and self-applied topical fluorides in preventing dental root caries. Controlled clinical trials with any follow-up duration were included. MEDLINE, PubMed, Embase, Scopus, and Cochrane Library were searched. Two reviewers independently carried out the selection of studies, data extraction, risk-of-bias assessments, and assessment of the certainty in the evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Fixed effects model and frequentist approach were used in the network meta-analyses. Nine clinical trials involving 4,030 participants were included. Five professionally applied and 7 self-applied topical fluoride agents or combinations were included in the meta-analyses. Compared to control group, 38% silver diamine fluoride solution, 5% sodium fluoride varnish, and 1.2% acidulated phosphate fluoride reduced root caries increment after 2 y (ranging from 0.59 to 0.85 mean decayed or filled root [DF-root]). Fluoride mouth rinse and fluoride toothpaste, used alone or in combination, reduced root caries increment after 1 y (ranging from 0.29 to 1.90 mean DF-root). Among the professionally applied topical fluorides reviewed, an annually applied 38% silver diamine fluoride (SDF) solution combined with oral health education is most likely to be the most effective in preventing dental root caries. Among the reviewed self-applied topical fluoride methods, daily use of a 0.2% sodium fluoride (NaF) mouth rinse is most likely to be the most effective, followed by 1100 ppm to 1500 ppm fluoride toothpaste plus 0.05% NaF mouth rinse, and 1100 ppm to 1500 ppm fluoride toothpaste. |
Persistent Identifier | http://hdl.handle.net/10722/288025 |
ISSN | 2023 Impact Factor: 5.7 2023 SCImago Journal Rankings: 1.909 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | ZHANG, J | - |
dc.contributor.author | SARDANA, D | - |
dc.contributor.author | Li, KY | - |
dc.contributor.author | Leung, KCM | - |
dc.contributor.author | Lo, ECM | - |
dc.date.accessioned | 2020-10-05T12:06:46Z | - |
dc.date.available | 2020-10-05T12:06:46Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Journal of Dental Research, 2020, v. 99 n. 5, p. 506-513 | - |
dc.identifier.issn | 0022-0345 | - |
dc.identifier.uri | http://hdl.handle.net/10722/288025 | - |
dc.description.abstract | The aim of this systematic review and network meta-analysis was to summarize the direct and indirect clinical evidence on the effectiveness of professionally applied and self-applied topical fluorides in preventing dental root caries. Controlled clinical trials with any follow-up duration were included. MEDLINE, PubMed, Embase, Scopus, and Cochrane Library were searched. Two reviewers independently carried out the selection of studies, data extraction, risk-of-bias assessments, and assessment of the certainty in the evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Fixed effects model and frequentist approach were used in the network meta-analyses. Nine clinical trials involving 4,030 participants were included. Five professionally applied and 7 self-applied topical fluoride agents or combinations were included in the meta-analyses. Compared to control group, 38% silver diamine fluoride solution, 5% sodium fluoride varnish, and 1.2% acidulated phosphate fluoride reduced root caries increment after 2 y (ranging from 0.59 to 0.85 mean decayed or filled root [DF-root]). Fluoride mouth rinse and fluoride toothpaste, used alone or in combination, reduced root caries increment after 1 y (ranging from 0.29 to 1.90 mean DF-root). Among the professionally applied topical fluorides reviewed, an annually applied 38% silver diamine fluoride (SDF) solution combined with oral health education is most likely to be the most effective in preventing dental root caries. Among the reviewed self-applied topical fluoride methods, daily use of a 0.2% sodium fluoride (NaF) mouth rinse is most likely to be the most effective, followed by 1100 ppm to 1500 ppm fluoride toothpaste plus 0.05% NaF mouth rinse, and 1100 ppm to 1500 ppm fluoride toothpaste. | - |
dc.language | eng | - |
dc.publisher | Sage Publications, Inc. The Journal's web site is located at http://jdr.sagepub.com/ | - |
dc.relation.ispartof | Journal of Dental Research | - |
dc.rights | Author(s), Contribution Title, Journal Title (Journal Volume Number and Issue Number) pp. xx-xx. Copyright © [year] (Copyright Holder). DOI: [DOI number]. | - |
dc.subject | dental caries | - |
dc.subject | prevention | - |
dc.subject | systematic review | - |
dc.subject | fluorides | - |
dc.subject | aged | - |
dc.title | Topical fluoride to prevent root caries: systematic review with network meta-analysis | - |
dc.type | Article | - |
dc.identifier.email | Li, KY: skyli@hku.hk | - |
dc.identifier.email | Leung, KCM: kcmleung@hku.hk | - |
dc.identifier.email | Lo, ECM: edward-lo@hku.hk | - |
dc.identifier.authority | Leung, KCM=rp00032 | - |
dc.identifier.authority | Lo, ECM=rp00015 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1177/0022034520906384 | - |
dc.identifier.pmid | 32142400 | - |
dc.identifier.scopus | eid_2-s2.0-85081921508 | - |
dc.identifier.hkuros | 315567 | - |
dc.identifier.volume | 99 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 506 | - |
dc.identifier.epage | 513 | - |
dc.identifier.isi | WOS:000523818500001 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 0022-0345 | - |