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Book Chapter: Radiotherapy for Cervical Esophageal Squamous Cell Carcinoma

TitleRadiotherapy for Cervical Esophageal Squamous Cell Carcinoma
Authors
KeywordsCervical esophageal cancer
Laryngeal preservation
Chemoradiotherapy
Intensity modulated radiotherapy
Issue Date2020
PublisherHumana.
Citation
Radiotherapy for Cervical Esophageal Squamous Cell Carcinoma. In Lam, AK (Ed.), Esophageal Squamous Cell Carcinoma: Methods and Protocols, p. 295-305. New York, NY: Humana, 2020 How to Cite?
AbstractCervical esophageal carcinoma (CEC) is rare, accounting for 2–10% of esophageal cancers and is mostly squamous cell carcinoma. Because of the anatomical proximity of CEC to larynx, surgical treatment would involve pharyngo-laryngo-esophagectomy (PLE) with inherent high mortality and morbidity. Laryngeal preservation is an important consideration, and definitive chemoradiotherapy is the recommended treatment. Treatment strategy of CEC can be more akin to treatment for head and neck cancers than to thoracic esophageal cancers. Since the exact location, extent of primary and nodal metastasis varies between patients, radiotherapy treatment needs to be individualized. The optimal radiation dose for CEC is uncertain, but retrospective data suggests that higher radiation dose of at least 60 Gy is associated with better local control and survival. Advanced radiotherapy technique, like intensity modulated radiotherapy, is usually required to achieve high dose to tumor while protecting normal tissues from excessive radiation.
Persistent Identifierhttp://hdl.handle.net/10722/287875
ISBN
ISSN
2023 SCImago Journal Rankings: 0.399
Series/Report no.Methods in Molecular Biology ; 2129

 

DC FieldValueLanguage
dc.contributor.authorKwong, DLW-
dc.contributor.authorChan, WLW-
dc.contributor.authorLam, KO-
dc.date.accessioned2020-10-05T12:04:31Z-
dc.date.available2020-10-05T12:04:31Z-
dc.date.issued2020-
dc.identifier.citationRadiotherapy for Cervical Esophageal Squamous Cell Carcinoma. In Lam, AK (Ed.), Esophageal Squamous Cell Carcinoma: Methods and Protocols, p. 295-305. New York, NY: Humana, 2020-
dc.identifier.isbn9781071603765-
dc.identifier.issn1064-3745-
dc.identifier.urihttp://hdl.handle.net/10722/287875-
dc.description.abstractCervical esophageal carcinoma (CEC) is rare, accounting for 2–10% of esophageal cancers and is mostly squamous cell carcinoma. Because of the anatomical proximity of CEC to larynx, surgical treatment would involve pharyngo-laryngo-esophagectomy (PLE) with inherent high mortality and morbidity. Laryngeal preservation is an important consideration, and definitive chemoradiotherapy is the recommended treatment. Treatment strategy of CEC can be more akin to treatment for head and neck cancers than to thoracic esophageal cancers. Since the exact location, extent of primary and nodal metastasis varies between patients, radiotherapy treatment needs to be individualized. The optimal radiation dose for CEC is uncertain, but retrospective data suggests that higher radiation dose of at least 60 Gy is associated with better local control and survival. Advanced radiotherapy technique, like intensity modulated radiotherapy, is usually required to achieve high dose to tumor while protecting normal tissues from excessive radiation.-
dc.languageeng-
dc.publisherHumana.-
dc.relation.ispartofEsophageal Squamous Cell Carcinoma: Methods and Protocols-
dc.relation.ispartofseriesMethods in Molecular Biology ; 2129-
dc.subjectCervical esophageal cancer-
dc.subjectLaryngeal preservation-
dc.subjectChemoradiotherapy-
dc.subjectIntensity modulated radiotherapy-
dc.titleRadiotherapy for Cervical Esophageal Squamous Cell Carcinoma-
dc.typeBook_Chapter-
dc.identifier.emailKwong, DLW: dlwkwong@hku.hk-
dc.identifier.emailChan, WLW: winglok@hku.hk-
dc.identifier.emailLam, KO: lamkaon@hku.hk-
dc.identifier.authorityKwong, DLW=rp00414-
dc.identifier.authorityChan, WLW=rp02541-
dc.identifier.authorityLam, KO=rp01501-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/978-1-0716-0377-2_22-
dc.identifier.scopuseid_2-s2.0-85079360621-
dc.identifier.hkuros314731-
dc.identifier.hkuros317879-
dc.identifier.spage295-
dc.identifier.epage305-
dc.publisher.placeNew York, NY-
dc.identifier.issnl1064-3745-

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