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Article: Emulsion Cross-Linking Technique for Human Fibroblast Encapsulation

TitleEmulsion Cross-Linking Technique for Human Fibroblast Encapsulation
Authors
Chaemsawang, WPrasongchea, WPapadopoulos, KSukrong, SKao, WJWattanaarsakit, P
Keywordsaqueous solution
cell death
cell encapsulation
cell structure
cell survival
Issue Date2018
PublisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/ijbm/
Citation
International Journal of Biomaterials, 2018, v. 2018, p. 9317878:1-9317878:6 How to Cite?
DOI: http://dx.doi.org/10.1155/2018/9317878
AbstractMicroencapsulation with biodegradable polymers has potential application in drug and cell delivery systems and is currently used in probiotic delivery. In the present study, microcapsules of human fibroblast cells (CRL2522) were prepared by emulsion cross-linking technique. Tween 80 surfactant at a 2% concentration through phase inversion resulted in the most efficient and stable size, morphology, and the cells survival at least 50% on day 14. Emulsion cross-linking microcapsule preparation resulted in smaller and possibly more diverse particles that can be developed clinically to deliver encapsulated mammalian cells for future disease treatments.
Persistent Identifierhttp://hdl.handle.net/10722/287270
ISSN
1687-8787
2023 Impact Factor: 3.0
2023 SCImago Journal Rankings: 0.495
PubMed Central ID
PMC6076944
ISI Accession Number ID
WOS:000439802900001

 

DC FieldValueLanguage
dc.contributor.authorChaemsawang, W-
dc.contributor.authorPrasongchea, W-
dc.contributor.authorPapadopoulos, K-
dc.contributor.authorSukrong, S-
dc.contributor.authorKao, WJ-
dc.contributor.authorWattanaarsakit, P-
dc.date.accessioned2020-09-22T02:58:26Z-
dc.date.available2020-09-22T02:58:26Z-
dc.date.issued2018-
dc.identifier.citationInternational Journal of Biomaterials, 2018, v. 2018, p. 9317878:1-9317878:6-
dc.identifier.issn1687-8787-
dc.identifier.urihttp://hdl.handle.net/10722/287270-
dc.description.abstractMicroencapsulation with biodegradable polymers has potential application in drug and cell delivery systems and is currently used in probiotic delivery. In the present study, microcapsules of human fibroblast cells (CRL2522) were prepared by emulsion cross-linking technique. Tween 80 surfactant at a 2% concentration through phase inversion resulted in the most efficient and stable size, morphology, and the cells survival at least 50% on day 14. Emulsion cross-linking microcapsule preparation resulted in smaller and possibly more diverse particles that can be developed clinically to deliver encapsulated mammalian cells for future disease treatments.-
dc.languageeng-
dc.publisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/ijbm/-
dc.relation.ispartofInternational Journal of Biomaterials-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectaqueous solution-
dc.subjectcell death-
dc.subjectcell encapsulation-
dc.subjectcell structure-
dc.subjectcell survival-
dc.titleEmulsion Cross-Linking Technique for Human Fibroblast Encapsulation-
dc.typeArticle-
dc.identifier.emailKao, WJ: wjkao@hku.hk-
dc.identifier.authorityKao, WJ=rp02076-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1155/2018/9317878-
dc.identifier.pmid30105055-
dc.identifier.pmcidPMC6076944-
dc.identifier.scopuseid_2-s2.0-85050792419-
dc.identifier.hkuros314499-
dc.identifier.volume2018-
dc.identifier.spage9317878:1-
dc.identifier.epage9317878:6-
dc.identifier.isiWOS:000439802900001-
dc.publisher.placeUnited States-
dc.identifier.issnl1687-8787-

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