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- Publisher Website: 10.1038/emi.2015.20
- Scopus: eid_2-s2.0-84979500468
- PMID: 26038769
- WOS: WOS:000352313800002
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Article: Understanding the interplay between host immunity and Epstein-Barr virus in NPC patients
Title | Understanding the interplay between host immunity and Epstein-Barr virus in NPC patients |
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Authors | |
Keywords | Innate immunity EBV Adaptive immunity Immune evasion NPC |
Issue Date | 2015 |
Citation | Emerging Microbes and Infections, 2015, v. 4, n. 3, article no. e20 How to Cite? |
Abstract | © 2015 SSCC. Epstein-Barr virus (EBV) has been used as a paradigm for studying host-virus interactions, not only because of its importance as a human oncogenic virus associated with several malignancies including nasopharyngeal carcinoma (NPC) but also owing to its sophisticated strategies to subvert the host antiviral responses. An understanding of the interplay between EBV and NPC is critical for the development of EBV-targeted immunotherapy. Here, we summarize the current knowledge regarding the host immune responses and EBV immune evasion mechanisms in the context of NPC. |
Persistent Identifier | http://hdl.handle.net/10722/285775 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Shen, Yong | - |
dc.contributor.author | Zhang, Suzhan | - |
dc.contributor.author | Sun, Ren | - |
dc.contributor.author | Wu, Tingting | - |
dc.contributor.author | Qian, Jing | - |
dc.date.accessioned | 2020-08-18T04:56:36Z | - |
dc.date.available | 2020-08-18T04:56:36Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Emerging Microbes and Infections, 2015, v. 4, n. 3, article no. e20 | - |
dc.identifier.uri | http://hdl.handle.net/10722/285775 | - |
dc.description.abstract | © 2015 SSCC. Epstein-Barr virus (EBV) has been used as a paradigm for studying host-virus interactions, not only because of its importance as a human oncogenic virus associated with several malignancies including nasopharyngeal carcinoma (NPC) but also owing to its sophisticated strategies to subvert the host antiviral responses. An understanding of the interplay between EBV and NPC is critical for the development of EBV-targeted immunotherapy. Here, we summarize the current knowledge regarding the host immune responses and EBV immune evasion mechanisms in the context of NPC. | - |
dc.language | eng | - |
dc.relation.ispartof | Emerging Microbes and Infections | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Innate immunity | - |
dc.subject | EBV | - |
dc.subject | Adaptive immunity | - |
dc.subject | Immune evasion | - |
dc.subject | NPC | - |
dc.title | Understanding the interplay between host immunity and Epstein-Barr virus in NPC patients | - |
dc.type | Article | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1038/emi.2015.20 | - |
dc.identifier.pmid | 26038769 | - |
dc.identifier.pmcid | PMC4395660 | - |
dc.identifier.scopus | eid_2-s2.0-84979500468 | - |
dc.identifier.volume | 4 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | article no. e20 | - |
dc.identifier.epage | article no. e20 | - |
dc.identifier.eissn | 2222-1751 | - |
dc.identifier.isi | WOS:000352313800002 | - |
dc.identifier.issnl | 2222-1751 | - |