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Article: Expanding indications for liver transplant: tumor and patient factors

TitleExpanding indications for liver transplant: tumor and patient factors
Authors
KeywordsLiver transplant
Hepatocellular carcinoma
Surgical indication
Issue Date2020
PublisherGut and Liver, Editorial Office. The Journal's web site is located at http://www.gutnliver.org/
Citation
Gut and Liver, 2020, Epub 2020-02-28 How to Cite?
AbstractDuring the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding ever since. The aim of this review is to provide an overview of such an expansion of scope. Various criteria have been proposed to expand the eligibility of patients with hepatocellular carcinoma exceeding the Milan criteria for liver transplant. Furthermore, liver transplant is increasingly performed as a treatment modality for cholangiocarcinoma, neuroendocrine liver metastasis and colorectal liver metastasis. The number of elderly patients receiving liver transplant is on the rise. Combined organ transplantation has also been adopted to treat patients with multiple organ failure. Going forward, further development of preoperative noninvasive predictors in tumor, patient and even donor factors is needed to identify patients at risk of poor outcomes and hence optimize patient management.
Persistent Identifierhttp://hdl.handle.net/10722/285320
ISSN
2019 Impact Factor: 3.141
2015 SCImago Journal Rankings: 0.848
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChu, KKW-
dc.contributor.authorWong, KHC-
dc.contributor.authorChok, KSH-
dc.date.accessioned2020-08-18T03:52:23Z-
dc.date.available2020-08-18T03:52:23Z-
dc.date.issued2020-
dc.identifier.citationGut and Liver, 2020, Epub 2020-02-28-
dc.identifier.issn1976-2283-
dc.identifier.urihttp://hdl.handle.net/10722/285320-
dc.description.abstractDuring the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding ever since. The aim of this review is to provide an overview of such an expansion of scope. Various criteria have been proposed to expand the eligibility of patients with hepatocellular carcinoma exceeding the Milan criteria for liver transplant. Furthermore, liver transplant is increasingly performed as a treatment modality for cholangiocarcinoma, neuroendocrine liver metastasis and colorectal liver metastasis. The number of elderly patients receiving liver transplant is on the rise. Combined organ transplantation has also been adopted to treat patients with multiple organ failure. Going forward, further development of preoperative noninvasive predictors in tumor, patient and even donor factors is needed to identify patients at risk of poor outcomes and hence optimize patient management.-
dc.languageeng-
dc.publisherGut and Liver, Editorial Office. The Journal's web site is located at http://www.gutnliver.org/-
dc.relation.ispartofGut and Liver-
dc.rightsGut and Liver. Copyright © Gut and Liver, Editorial Office.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectLiver transplant-
dc.subjectHepatocellular carcinoma-
dc.subjectSurgical indication-
dc.titleExpanding indications for liver transplant: tumor and patient factors-
dc.typeArticle-
dc.identifier.emailChok, KSH: chok6275@hku.hk-
dc.identifier.authorityChok, KSH=rp02110-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.5009/gnl19265-
dc.identifier.pmid32102130-
dc.identifier.hkuros312949-
dc.identifier.volumeEpub 2020-02-28-
dc.identifier.isiWOS:000608283000004-
dc.publisher.placeKorea, Republic of-
dc.identifier.issnl1976-2283-

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