File Download
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.5009/gnl19265
- Scopus: eid_2-s2.0-85100070705
- PMID: 32102130
- WOS: WOS:000608283000004
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Expanding indications for liver transplant: tumor and patient factors
Title | Expanding indications for liver transplant: tumor and patient factors |
---|---|
Authors | |
Keywords | Liver transplant Hepatocellular carcinoma Surgical indication |
Issue Date | 2020 |
Publisher | Gut and Liver, Editorial Office. The Journal's web site is located at http://www.gutnliver.org/ |
Citation | Gut and Liver, 2020, Epub 2020-02-28 How to Cite? |
Abstract | During the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding ever since. The aim of this review is to provide an overview of such an expansion of scope. Various criteria have been proposed to expand the eligibility of patients with hepatocellular carcinoma exceeding the Milan criteria for liver transplant. Furthermore, liver transplant is increasingly performed as a treatment modality for cholangiocarcinoma, neuroendocrine liver metastasis and colorectal liver metastasis. The number of elderly patients receiving liver transplant is on the rise. Combined organ transplantation has also been adopted to treat patients with multiple organ failure. Going forward, further development of preoperative noninvasive predictors in tumor, patient and even donor factors is needed to identify patients at risk of poor outcomes and hence optimize patient management. |
Persistent Identifier | http://hdl.handle.net/10722/285320 |
ISSN | 2023 Impact Factor: 3.4 2023 SCImago Journal Rankings: 1.255 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chu, KKW | - |
dc.contributor.author | Wong, KHC | - |
dc.contributor.author | Chok, KSH | - |
dc.date.accessioned | 2020-08-18T03:52:23Z | - |
dc.date.available | 2020-08-18T03:52:23Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Gut and Liver, 2020, Epub 2020-02-28 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | http://hdl.handle.net/10722/285320 | - |
dc.description.abstract | During the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding ever since. The aim of this review is to provide an overview of such an expansion of scope. Various criteria have been proposed to expand the eligibility of patients with hepatocellular carcinoma exceeding the Milan criteria for liver transplant. Furthermore, liver transplant is increasingly performed as a treatment modality for cholangiocarcinoma, neuroendocrine liver metastasis and colorectal liver metastasis. The number of elderly patients receiving liver transplant is on the rise. Combined organ transplantation has also been adopted to treat patients with multiple organ failure. Going forward, further development of preoperative noninvasive predictors in tumor, patient and even donor factors is needed to identify patients at risk of poor outcomes and hence optimize patient management. | - |
dc.language | eng | - |
dc.publisher | Gut and Liver, Editorial Office. The Journal's web site is located at http://www.gutnliver.org/ | - |
dc.relation.ispartof | Gut and Liver | - |
dc.rights | Gut and Liver. Copyright © Gut and Liver, Editorial Office. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Liver transplant | - |
dc.subject | Hepatocellular carcinoma | - |
dc.subject | Surgical indication | - |
dc.title | Expanding indications for liver transplant: tumor and patient factors | - |
dc.type | Article | - |
dc.identifier.email | Chok, KSH: chok6275@hku.hk | - |
dc.identifier.authority | Chok, KSH=rp02110 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.5009/gnl19265 | - |
dc.identifier.pmid | 32102130 | - |
dc.identifier.scopus | eid_2-s2.0-85100070705 | - |
dc.identifier.hkuros | 312949 | - |
dc.identifier.volume | Epub 2020-02-28 | - |
dc.identifier.isi | WOS:000608283000004 | - |
dc.publisher.place | Korea, Republic of | - |
dc.identifier.issnl | 1976-2283 | - |