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Article: Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong

TitleCharacteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong
Authors
KeywordsCommuter exposure
Black carbon
Transition metals
Cytotoxicity
Reactive oxygen species (ROS)
Issue Date2020
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/scitotenv
Citation
Science of the Total Environment, 2020, v. 742, p. article no. 140501 How to Cite?
AbstractEpidemiological studies have demonstrated significant associations between traffic-related air pollution and adverse health outcomes. Personal exposure to fine particles (PM2.5) in transport microenvironments and their toxicological properties remain to be investigated. Commuter exposures were investigated in public transport systems (including the buses and Mass Transit Railway (MTR)) along two sampling routes in Hong Kong. Real-time sampling for PM2.5 and black carbon (BC), along with integrated PM2.5 sampling, were performed during the warm and cold season of 2016–2017, respectively. Commuter exposure to BC during 3-hour commuting time exhibited a wider range, from 3.4 to 4.6 μg/m3 on the bus and 5.5 to 8.7 μg/m3 in MTR cabin (p < .05). PM2.5 mass and major chemical constituents (including organic carbon (OC), elemental carbon (EC), and metals) were analyzed. Cytotoxicity, including cellular reactive oxygen species (ROS) production, was determined in addition to acellular ROS generation. PM2.5 treatment promoted the ROS generation in a concentration-dependent manner. Consistent diurnal variations were observed for commuter exposure to BC and PM2.5 components, along with cellular and acellular ROS generation, which marked with two peaks during the morning (08:00–11:00) and evening rush hours (17:30–20:30). Commuter exposures in the MTR system were characterized by higher levels of PM2.5 and elemental components (e.g., Ca, Cr, Fe, Zn, Ba) compared to riding the bus, along with higher cellular and acellular ROS production (p < .01). These metals were attributed to different sources: rail tracks, wheels, brakes, and crustal origin. Weak to moderate associations were shown for the analyzed transition metals with PM2.5-induced cell viability and cellular ROS. Multiple linear regression analysis revealed that Ni, Zn, Mn, Fe, Ti, and Co attributed to cytotoxicity and ROS generation. These findings underscore the importance of commuter exposures and their toxic effects, urging effective mitigating strategies to protect human health.
Persistent Identifierhttp://hdl.handle.net/10722/284475
ISSN
2020 Impact Factor: 7.963
2015 SCImago Journal Rankings: 1.702
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChen, XC-
dc.contributor.authorCao, JJ-
dc.contributor.authorWard, TJ-
dc.contributor.authorTian, LW-
dc.contributor.authorNing, Z-
dc.contributor.authorGali, NK-
dc.contributor.authorAquilina, N-
dc.contributor.authorYim, SHL-
dc.contributor.authorQu, L-
dc.contributor.authorHo, KF-
dc.date.accessioned2020-08-07T08:58:09Z-
dc.date.available2020-08-07T08:58:09Z-
dc.date.issued2020-
dc.identifier.citationScience of the Total Environment, 2020, v. 742, p. article no. 140501-
dc.identifier.issn0048-9697-
dc.identifier.urihttp://hdl.handle.net/10722/284475-
dc.description.abstractEpidemiological studies have demonstrated significant associations between traffic-related air pollution and adverse health outcomes. Personal exposure to fine particles (PM2.5) in transport microenvironments and their toxicological properties remain to be investigated. Commuter exposures were investigated in public transport systems (including the buses and Mass Transit Railway (MTR)) along two sampling routes in Hong Kong. Real-time sampling for PM2.5 and black carbon (BC), along with integrated PM2.5 sampling, were performed during the warm and cold season of 2016–2017, respectively. Commuter exposure to BC during 3-hour commuting time exhibited a wider range, from 3.4 to 4.6 μg/m3 on the bus and 5.5 to 8.7 μg/m3 in MTR cabin (p < .05). PM2.5 mass and major chemical constituents (including organic carbon (OC), elemental carbon (EC), and metals) were analyzed. Cytotoxicity, including cellular reactive oxygen species (ROS) production, was determined in addition to acellular ROS generation. PM2.5 treatment promoted the ROS generation in a concentration-dependent manner. Consistent diurnal variations were observed for commuter exposure to BC and PM2.5 components, along with cellular and acellular ROS generation, which marked with two peaks during the morning (08:00–11:00) and evening rush hours (17:30–20:30). Commuter exposures in the MTR system were characterized by higher levels of PM2.5 and elemental components (e.g., Ca, Cr, Fe, Zn, Ba) compared to riding the bus, along with higher cellular and acellular ROS production (p < .01). These metals were attributed to different sources: rail tracks, wheels, brakes, and crustal origin. Weak to moderate associations were shown for the analyzed transition metals with PM2.5-induced cell viability and cellular ROS. Multiple linear regression analysis revealed that Ni, Zn, Mn, Fe, Ti, and Co attributed to cytotoxicity and ROS generation. These findings underscore the importance of commuter exposures and their toxic effects, urging effective mitigating strategies to protect human health.-
dc.languageeng-
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/scitotenv-
dc.relation.ispartofScience of the Total Environment-
dc.subjectCommuter exposure-
dc.subjectBlack carbon-
dc.subjectTransition metals-
dc.subjectCytotoxicity-
dc.subjectReactive oxygen species (ROS)-
dc.titleCharacteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong-
dc.typeArticle-
dc.identifier.emailChen, XC: chenxcui@hku.hk-
dc.identifier.emailTian, LW: linweit@hku.hk-
dc.identifier.authorityTian, LW=rp01991-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.scitotenv.2020.140501-
dc.identifier.pmid32622166-
dc.identifier.scopuseid_2-s2.0-85087103008-
dc.identifier.hkuros312384-
dc.identifier.volume742-
dc.identifier.spagearticle no. 140501-
dc.identifier.epagearticle no. 140501-
dc.identifier.isiWOS:000569416600009-
dc.publisher.placeNetherlands-
dc.identifier.issnl0048-9697-

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