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Article: Improved leg wound healing with endoscopic saphenous vein harvest in coronary artery bypass graft surgery: A prospective randomized study in asian population

TitleImproved leg wound healing with endoscopic saphenous vein harvest in coronary artery bypass graft surgery: A prospective randomized study in asian population
Authors
KeywordsAsia
clinical feature
clinical trial
controlled clinical trial
controlled study
Issue Date2008
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1540-8191
Citation
Journal of Cardiac Surgery, 2008, v. 23 n. 6, p. 633-637 How to Cite?
AbstractObjective : Conventional open saphenous vein harvest (OVH) for coronary artery bypass graft surgery is often associated with significant pain and morbidity. This study aims to determine whether endoscopic saphenous vein harvest (EVH) reduces leg wound morbidity and improves patient satisfaction as compared to OVH in Asian population. Methods : Between March 2005 and June 2006, 120 patients who underwent isolated CABG were prospectively randomized into EVH (n = 60) and OVH (n = 60) groups. VirtuoSaph™ (Terumo Cardiovascular Corp., Ann Arbor, MI, USA) harvesting system was used for EVH. We analyzed leg wound complications (ASEPSIS score), postoperative pain, satisfaction, and clinical outcomes. Fisher's exact test and Mann‐Whitney U test were used for categorical and continuous variables analysis respectively. Results : Six patients in the EVH group required conversion to open technique. Both groups had matched demographic characteristics and risk factors. Mean numbers of grafts performed were 3.2 ± 0.6 (EVH n = 54) and 3.0 ± 0.7 (OVH n = 60) (p = 0.03). ASEPSIS scores at postoperation days three, seven, and 21 were significantly lower in the EVH group than the OVH group (p = 0.02, p = 0.002 and p = 0.01, respectively). Wound pain scores at postoperative days three, seven, and 21 were significantly lower in the EVH group (p = 0.000, p = 0.001 and p = 0.000 respectively). Wound numbness was found in 5.7% of the EVH group and 33.3% of the OVH group patients (p = 0.01). [Six patients required conversion to open technique.] There was one hospital mortality (OVH group) and major postoperative complications were not significantly different between the groups. Conclusion : EVH system is a safe and effective alternative to OVH with better wound healing, reduced postoperative pain, and wound numbness. However, the higher conversion rate to OVH in Asian patients requires further evaluation.
Persistent Identifierhttp://hdl.handle.net/10722/283273
ISSN
2023 Impact Factor: 1.3
2023 SCImago Journal Rankings: 0.455
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorAu, WKT-
dc.contributor.authorChiu, SW-
dc.contributor.authorSun, MP-
dc.contributor.authorLam, KT-
dc.contributor.authorLin, MF-
dc.contributor.authorChui, WH-
dc.contributor.authorYeung, CL-
dc.contributor.authorCheng, LC-
dc.date.accessioned2020-06-22T02:54:25Z-
dc.date.available2020-06-22T02:54:25Z-
dc.date.issued2008-
dc.identifier.citationJournal of Cardiac Surgery, 2008, v. 23 n. 6, p. 633-637-
dc.identifier.issn0886-0440-
dc.identifier.urihttp://hdl.handle.net/10722/283273-
dc.description.abstractObjective : Conventional open saphenous vein harvest (OVH) for coronary artery bypass graft surgery is often associated with significant pain and morbidity. This study aims to determine whether endoscopic saphenous vein harvest (EVH) reduces leg wound morbidity and improves patient satisfaction as compared to OVH in Asian population. Methods : Between March 2005 and June 2006, 120 patients who underwent isolated CABG were prospectively randomized into EVH (n = 60) and OVH (n = 60) groups. VirtuoSaph™ (Terumo Cardiovascular Corp., Ann Arbor, MI, USA) harvesting system was used for EVH. We analyzed leg wound complications (ASEPSIS score), postoperative pain, satisfaction, and clinical outcomes. Fisher's exact test and Mann‐Whitney U test were used for categorical and continuous variables analysis respectively. Results : Six patients in the EVH group required conversion to open technique. Both groups had matched demographic characteristics and risk factors. Mean numbers of grafts performed were 3.2 ± 0.6 (EVH n = 54) and 3.0 ± 0.7 (OVH n = 60) (p = 0.03). ASEPSIS scores at postoperation days three, seven, and 21 were significantly lower in the EVH group than the OVH group (p = 0.02, p = 0.002 and p = 0.01, respectively). Wound pain scores at postoperative days three, seven, and 21 were significantly lower in the EVH group (p = 0.000, p = 0.001 and p = 0.000 respectively). Wound numbness was found in 5.7% of the EVH group and 33.3% of the OVH group patients (p = 0.01). [Six patients required conversion to open technique.] There was one hospital mortality (OVH group) and major postoperative complications were not significantly different between the groups. Conclusion : EVH system is a safe and effective alternative to OVH with better wound healing, reduced postoperative pain, and wound numbness. However, the higher conversion rate to OVH in Asian patients requires further evaluation.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1540-8191-
dc.relation.ispartofJournal of Cardiac Surgery-
dc.rightsPreprint This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Postprint This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.-
dc.subjectAsia-
dc.subjectclinical feature-
dc.subjectclinical trial-
dc.subjectcontrolled clinical trial-
dc.subjectcontrolled study-
dc.titleImproved leg wound healing with endoscopic saphenous vein harvest in coronary artery bypass graft surgery: A prospective randomized study in asian population-
dc.typeArticle-
dc.identifier.emailAu, WKT: auwkt@hkucc.hku.hk-
dc.identifier.emailLam, KT: tailam@hkucc.hku.hk-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1540-8191.2008.00659.x-
dc.identifier.pmid19016987-
dc.identifier.scopuseid_2-s2.0-55149105690-
dc.identifier.hkuros310496-
dc.identifier.volume23-
dc.identifier.issue6-
dc.identifier.spage633-
dc.identifier.epage637-
dc.identifier.isiWOS:000260499400009-
dc.publisher.placeUnited States-
dc.identifier.issnl0886-0440-

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