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Article: Lutein Supplementation for Eye Diseases
Title | Lutein Supplementation for Eye Diseases |
---|---|
Authors | |
Keywords | age-related macular degeneration antioxidant carotenoid diabetic retinopathy myopia |
Issue Date | 2020 |
Publisher | MDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/nutrients/ |
Citation | Nutrients, 2020, v. 12 n. 6, p. article no. 1721 How to Cite? |
Abstract | Lutein is one of the few xanthophyll carotenoids that is found in high concentration in the macula of human retina. As de novo synthesis of lutein within the human body is impossible, lutein can only be obtained from diet. It is a natural substance abundant in egg yolk and dark green leafy vegetables. Many basic and clinical studies have reported lutein’s anti-oxidative and anti-inflammatory properties in the eye, suggesting its beneficial effects on protection and alleviation of ocular diseases such as age-related macular degeneration, diabetic retinopathy, retinopathy of prematurity, myopia, and cataract. Most importantly, lutein is categorized as Generally Regarded as Safe (GRAS), posing minimal side-effects upon long term consumption. In this review, we will discuss the chemical structure and properties of lutein as well as its application and safety as a nutritional supplement. Finally, the effects of lutein consumption on the aforementioned eye diseases will be reviewed. |
Persistent Identifier | http://hdl.handle.net/10722/283242 |
ISSN | 2023 Impact Factor: 4.8 2023 SCImago Journal Rankings: 1.301 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Li, LH | - |
dc.contributor.author | Lee, JCY | - |
dc.contributor.author | LEUNG, HH | - |
dc.contributor.author | Lam, WC | - |
dc.contributor.author | Fu, Z | - |
dc.contributor.author | Lo, ACY | - |
dc.date.accessioned | 2020-06-22T02:54:01Z | - |
dc.date.available | 2020-06-22T02:54:01Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Nutrients, 2020, v. 12 n. 6, p. article no. 1721 | - |
dc.identifier.issn | 2072-6643 | - |
dc.identifier.uri | http://hdl.handle.net/10722/283242 | - |
dc.description.abstract | Lutein is one of the few xanthophyll carotenoids that is found in high concentration in the macula of human retina. As de novo synthesis of lutein within the human body is impossible, lutein can only be obtained from diet. It is a natural substance abundant in egg yolk and dark green leafy vegetables. Many basic and clinical studies have reported lutein’s anti-oxidative and anti-inflammatory properties in the eye, suggesting its beneficial effects on protection and alleviation of ocular diseases such as age-related macular degeneration, diabetic retinopathy, retinopathy of prematurity, myopia, and cataract. Most importantly, lutein is categorized as Generally Regarded as Safe (GRAS), posing minimal side-effects upon long term consumption. In this review, we will discuss the chemical structure and properties of lutein as well as its application and safety as a nutritional supplement. Finally, the effects of lutein consumption on the aforementioned eye diseases will be reviewed. | - |
dc.language | eng | - |
dc.publisher | MDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/nutrients/ | - |
dc.relation.ispartof | Nutrients | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | age-related macular degeneration | - |
dc.subject | antioxidant | - |
dc.subject | carotenoid | - |
dc.subject | diabetic retinopathy | - |
dc.subject | myopia | - |
dc.title | Lutein Supplementation for Eye Diseases | - |
dc.type | Article | - |
dc.identifier.email | Lee, JCY: jettylee@hku.hk | - |
dc.identifier.email | Lam, WC: waichlam@hku.hk | - |
dc.identifier.email | Lo, ACY: amylo@hku.hk | - |
dc.identifier.authority | Lee, JCY=rp01511 | - |
dc.identifier.authority | Lam, WC=rp02162 | - |
dc.identifier.authority | Lo, ACY=rp00425 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3390/nu12061721 | - |
dc.identifier.pmid | 32526861 | - |
dc.identifier.scopus | eid_2-s2.0-85086162134 | - |
dc.identifier.hkuros | 310418 | - |
dc.identifier.volume | 12 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | article no. 1721 | - |
dc.identifier.epage | article no. 1721 | - |
dc.identifier.isi | WOS:000549252200001 | - |
dc.publisher.place | Switzerland | - |
dc.identifier.issnl | 2072-6643 | - |