Effect of novel FUDMA-TEGDMA-BAG resin on dentine adhesion

Abstract

Objectives: Aim of this laboratory study was to investigate effect of novel FUDMA-monomer on TEGDMA-resin with experimental bioactive glass on dentine adhesion. Methods: Experimental resin was prepared using experimental 70wt% of novel fluorinated dimethacrylate (FUDMA), 30wt% of triethyleneglycol dimethacrylate (TEGDMA) with the addition to accelerator and initiator. The resin blend was further mixed with 10wt% and 70wt% of acetone for preparation of adhesive and primer respectively. Silanized experimental bioactive glass fillers (BAG, 58SiO2-37CaO-5P2O5) were added in experimental resin in 0wt%, 2wt%, 5wt%, and 10wt%. Commercial 3-step resin adhesive (AdperTMScotchbond-Multipurpose) was used as the control. Next, 6mm x 4mm x 4mm Class I cavities were prepared on freshly extracted human molars (ethical approval). Molars were randomly divided into two groups. One group was restored under simulated pulpal pressure (SPP) technique and other without SPP. The exposed dentine was etched with 32% phosphoric acid-gel followed by rinsing with DI water. Primer and adhesive were applied, cavities were restored with FiltekZ250 (3M-ESPE) using the incremental technique. All groups were stored in deionized water and were tested after 24 h, 30 days, 6 months and 12 months. Samples were cut into 1 mm2 beams and were subjected to µTBS test. Data were analyzed by multiple ANOVA and the level of significance was set P=0.05. Results: Mean MTBS of SPP-groups were significantly lower than MTBS (no-SPP) (P<0.05). Highest no-SPP (24h,5%BAG) was 23.8±3MPa and no-SPP (12 months,5%BAG) was 20.3±1.1MPa, SPP (24h,5%BAG) was 18.9±3.1MPa, SPP (12months,5%BAG) = 15.8±2.7MPa. Lowest: SPP (24h,no-BAG) = 16.2±4.9MPa, SPP (12months,no-BAG) = 10.3±2.2MPa. Control: no-SPP (24h,no-BAG) = 26.1±3.4MPa, No-SPP (12months,no-BAG) = 18.9±2.9MPa, SPP (24h,no-BAG) = 19.2±4.2MPa and SPP (12months,no-BAG) = 15.5±2.9MPa. More adhesive failures were observed in groups bonded with SPP than without SPP. Conclusions: FUDMA-TEGDMA-BAG based experimental resin has the potential to bond strongly to dentine.