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Article: Ligand-enabled triple C-H activation reactions: One-pot synthesis of diverse 4-aryl-2-quinolinones from propionamides

TitleLigand-enabled triple C-H activation reactions: One-pot synthesis of diverse 4-aryl-2-quinolinones from propionamides
Authors
Keywordsquinolinone
dehydrogenation
C-H activation
arylation
amidation
Issue Date2014
Citation
Angewandte Chemie - International Edition, 2014, v. 53, n. 26, p. 6692-6695 How to Cite?
AbstractDiverse 4-aryl-2-quinolinones are prepared from propionamides in one pot by ligand-promoted triple sequential C-H activation reactions and a stereospecific Heck reaction. In these cascade reactions, three new C-C bonds and one C-N bond are formed to rapidly build molecular complexity from propionic acid. Building complexity: Diverse 4-aryl-2-quinolinones such as 1 are prepared from propionamides in one pot by pyridine ligand-promoted triple sequential C-H activation reactions and a stereospecific Heck reaction. In these cascade reactions, three new C-C bonds and one C-N bond are formed to rapidly build molecular complexity from propionic acid. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Persistent Identifierhttp://hdl.handle.net/10722/276993
ISSN
2023 Impact Factor: 16.1
2023 SCImago Journal Rankings: 5.300
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorDeng, Youqian-
dc.contributor.authorGong, Wei-
dc.contributor.authorHe, Jian-
dc.contributor.authorYu, Jin Quan-
dc.date.accessioned2019-09-18T08:35:16Z-
dc.date.available2019-09-18T08:35:16Z-
dc.date.issued2014-
dc.identifier.citationAngewandte Chemie - International Edition, 2014, v. 53, n. 26, p. 6692-6695-
dc.identifier.issn1433-7851-
dc.identifier.urihttp://hdl.handle.net/10722/276993-
dc.description.abstractDiverse 4-aryl-2-quinolinones are prepared from propionamides in one pot by ligand-promoted triple sequential C-H activation reactions and a stereospecific Heck reaction. In these cascade reactions, three new C-C bonds and one C-N bond are formed to rapidly build molecular complexity from propionic acid. Building complexity: Diverse 4-aryl-2-quinolinones such as 1 are prepared from propionamides in one pot by pyridine ligand-promoted triple sequential C-H activation reactions and a stereospecific Heck reaction. In these cascade reactions, three new C-C bonds and one C-N bond are formed to rapidly build molecular complexity from propionic acid. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.-
dc.languageeng-
dc.relation.ispartofAngewandte Chemie - International Edition-
dc.subjectquinolinone-
dc.subjectdehydrogenation-
dc.subjectC-H activation-
dc.subjectarylation-
dc.subjectamidation-
dc.titleLigand-enabled triple C-H activation reactions: One-pot synthesis of diverse 4-aryl-2-quinolinones from propionamides-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/anie.201403878-
dc.identifier.pmid24828691-
dc.identifier.scopuseid_2-s2.0-84903120457-
dc.identifier.volume53-
dc.identifier.issue26-
dc.identifier.spage6692-
dc.identifier.epage6695-
dc.identifier.eissn1521-3773-
dc.identifier.isiWOS:000338021600019-
dc.identifier.issnl1433-7851-

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