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Article: Global Epidemiology of Bat Coronaviruses

TitleGlobal Epidemiology of Bat Coronaviruses
Authors
KeywordsGlobal
Epidemiology
Bat
Coronavirus
Alphacoronavirus
Betacoronavirus
Interspecies transmission
Host
Issue Date2019
PublisherMolecular Diversity Preservation International (MDPI) AG.. The Journal's web site is located at http://www.mdpi.com/journal/viruses
Citation
Viruses, 2019, v. 11 n. 2, article no. 174 How to Cite?
AbstractBats are a unique group of mammals of the order Chiroptera. They are highly diversified and are the group of mammals with the second largest number of species. Such highly diversified cell types and receptors facilitate them to be potential hosts of a large variety of viruses. Bats are the only group of mammals capable of sustained flight, which enables them to disseminate the viruses they harbor and enhance the chance of interspecies transmission. This article aims at reviewing the various aspects of the global epidemiology of bat coronaviruses (CoVs). Before the SARS epidemic, bats were not known to be hosts for CoVs. In the last 15 years, bats have been found to be hosts of >30 CoVs with complete genomes sequenced, and many more if those without genome sequences are included. Among the four CoV genera, only alphaCoVs and betaCoVs have been found in bats. As a whole, both alphaCoVs and betaCoVs have been detected from bats in Asia, Europe, Africa, North and South America and Australasia; but alphaCoVs seem to be more widespread than betaCoVs, and their detection rate is also higher. For betaCoVs, only those from subgenera Sarbecovirus, Merbecovirus, Nobecovirus and Hibecovirus have been detected in bats. Most notably, horseshoe bats are the reservoir of SARS-CoV, and several betaCoVs from subgenus Merbecovirus are closely related to MERS-CoV. In addition to the interactions among various bat species themselves, bat-animal and bat-human interactions, such as the presence of live bats in wildlife wet markets and restaurants in Southern China, are important for interspecies transmission of CoVs and may lead to devastating global outbreaks. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
Persistent Identifierhttp://hdl.handle.net/10722/276337
ISSN
2023 Impact Factor: 3.8
2023 SCImago Journal Rankings: 1.140
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, ACP-
dc.contributor.authorLi, X-
dc.contributor.authorLau, SKP-
dc.contributor.authorWoo, PCY-
dc.date.accessioned2019-09-10T03:01:03Z-
dc.date.available2019-09-10T03:01:03Z-
dc.date.issued2019-
dc.identifier.citationViruses, 2019, v. 11 n. 2, article no. 174-
dc.identifier.issn1999-4915-
dc.identifier.urihttp://hdl.handle.net/10722/276337-
dc.description.abstractBats are a unique group of mammals of the order Chiroptera. They are highly diversified and are the group of mammals with the second largest number of species. Such highly diversified cell types and receptors facilitate them to be potential hosts of a large variety of viruses. Bats are the only group of mammals capable of sustained flight, which enables them to disseminate the viruses they harbor and enhance the chance of interspecies transmission. This article aims at reviewing the various aspects of the global epidemiology of bat coronaviruses (CoVs). Before the SARS epidemic, bats were not known to be hosts for CoVs. In the last 15 years, bats have been found to be hosts of >30 CoVs with complete genomes sequenced, and many more if those without genome sequences are included. Among the four CoV genera, only alphaCoVs and betaCoVs have been found in bats. As a whole, both alphaCoVs and betaCoVs have been detected from bats in Asia, Europe, Africa, North and South America and Australasia; but alphaCoVs seem to be more widespread than betaCoVs, and their detection rate is also higher. For betaCoVs, only those from subgenera Sarbecovirus, Merbecovirus, Nobecovirus and Hibecovirus have been detected in bats. Most notably, horseshoe bats are the reservoir of SARS-CoV, and several betaCoVs from subgenus Merbecovirus are closely related to MERS-CoV. In addition to the interactions among various bat species themselves, bat-animal and bat-human interactions, such as the presence of live bats in wildlife wet markets and restaurants in Southern China, are important for interspecies transmission of CoVs and may lead to devastating global outbreaks. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.-
dc.languageeng-
dc.publisherMolecular Diversity Preservation International (MDPI) AG.. The Journal's web site is located at http://www.mdpi.com/journal/viruses-
dc.relation.ispartofViruses-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectGlobal-
dc.subjectEpidemiology-
dc.subjectBat-
dc.subjectCoronavirus-
dc.subjectAlphacoronavirus-
dc.subjectBetacoronavirus-
dc.subjectInterspecies transmission-
dc.subjectHost-
dc.titleGlobal Epidemiology of Bat Coronaviruses-
dc.typeArticle-
dc.identifier.emailLau, SKP: skplau@hkucc.hku.hk-
dc.identifier.emailWoo, PCY: pcywoo@hkucc.hku.hk-
dc.identifier.authorityLau, SKP=rp00486-
dc.identifier.authorityWoo, PCY=rp00430-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3390/v11020174-
dc.identifier.pmid30791586-
dc.identifier.pmcidPMC6409556-
dc.identifier.scopuseid_2-s2.0-85061964822-
dc.identifier.hkuros304173-
dc.identifier.volume11-
dc.identifier.issue2-
dc.identifier.spagearticle no. 174-
dc.identifier.epagearticle no. 174-
dc.identifier.isiWOS:000460803200084-
dc.publisher.placeSwitzerland-
dc.identifier.issnl1999-4915-

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