File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1159/000492312
- Scopus: eid_2-s2.0-85061749509
- PMID: 30943506
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Surgical treatment of advanced staged hypopharyngeal cancer
Title | Surgical treatment of advanced staged hypopharyngeal cancer |
---|---|
Authors | |
Keywords | cancer staging human hypopharynx hypopharynx tumor pathology |
Issue Date | 2019 |
Publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/ADORL |
Citation | Advances in Oto-Rhino-Laryngology, 2019, v. 83, p. 66-75 How to Cite? |
Abstract | It is not uncommon for patients with hypopharyngeal cancer to present at an advanced stage of disease. Surgical treatment provides a cure for the tumour with immediate relief from obstruction to the airway and the swallowing passage. Careful planning of surgery is important to ensure good outcome of treatment and prevent complications, some of which may be fatal. The shape of the hypopharynx resembles that of a funnel, with a wide circumference above in continuity with the oropharynx, and a small circumference below where it joins with the cervical oesophagus. As a result, while small tumours require the partial removal of the hypopharynx, large tumours, especially those involving the post-cricoid region, warrant a complete, circumferential pharyngectomy. For tumours that invade the cervical esophagus, transcervical approach is still feasible, and this is facilitated by the removal of the manubrium, allowing access to the tumour and resection with clear margins. In the presence of synchronous tumours lower down in the esophagus, pharyngo-laryngo-esophagectomy is indicated. Successful reconstruction of defects after tumour extirpation allows proper wound healing and early delivery of adjuvant radiotherapy. It is also important to ensure quick recovery of the long-term swallowing function. It ranges from the use of the soft tissue flap with skin island that is sutured as a patch to the remnants of the pharyngeal mucosa, to the use of a visceral flap, such as the free jejunal flap, to repair the circumferential pharyngectomy defects. The treatment protocol is personalized according to the extent of the tumour and the characteristics of the patients. |
Persistent Identifier | http://hdl.handle.net/10722/272981 |
ISSN | 2023 SCImago Journal Rankings: 0.547 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wei, WI | - |
dc.contributor.author | Chan, JYW | - |
dc.date.accessioned | 2019-08-06T09:20:20Z | - |
dc.date.available | 2019-08-06T09:20:20Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Advances in Oto-Rhino-Laryngology, 2019, v. 83, p. 66-75 | - |
dc.identifier.issn | 0065-3071 | - |
dc.identifier.uri | http://hdl.handle.net/10722/272981 | - |
dc.description.abstract | It is not uncommon for patients with hypopharyngeal cancer to present at an advanced stage of disease. Surgical treatment provides a cure for the tumour with immediate relief from obstruction to the airway and the swallowing passage. Careful planning of surgery is important to ensure good outcome of treatment and prevent complications, some of which may be fatal. The shape of the hypopharynx resembles that of a funnel, with a wide circumference above in continuity with the oropharynx, and a small circumference below where it joins with the cervical oesophagus. As a result, while small tumours require the partial removal of the hypopharynx, large tumours, especially those involving the post-cricoid region, warrant a complete, circumferential pharyngectomy. For tumours that invade the cervical esophagus, transcervical approach is still feasible, and this is facilitated by the removal of the manubrium, allowing access to the tumour and resection with clear margins. In the presence of synchronous tumours lower down in the esophagus, pharyngo-laryngo-esophagectomy is indicated. Successful reconstruction of defects after tumour extirpation allows proper wound healing and early delivery of adjuvant radiotherapy. It is also important to ensure quick recovery of the long-term swallowing function. It ranges from the use of the soft tissue flap with skin island that is sutured as a patch to the remnants of the pharyngeal mucosa, to the use of a visceral flap, such as the free jejunal flap, to repair the circumferential pharyngectomy defects. The treatment protocol is personalized according to the extent of the tumour and the characteristics of the patients. | - |
dc.language | eng | - |
dc.publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/ADORL | - |
dc.relation.ispartof | Advances in Oto-Rhino-Laryngology | - |
dc.rights | Advances in Oto-Rhino-Laryngology. Copyright © S Karger AG. | - |
dc.rights | This is the peer-reviewed but unedited manuscript version of the following article: [insert full citation, e.g., Cytogenet Genome Res 2014;142:227–238 (DOI: 10.1159/000361001)]. The final, published version is available at http://www.karger.com/?doi=[insert DOI number]. OR This is the un-reviewed and unedited manuscript version of the following article: [insert full citation, e.g., Cytogenet Genome Res 2014;142:227–238 (DOI: 10.1159/000361001)]. The final, published version is available at http://www.karger.com/?doi=[insert DOI number]. | - |
dc.subject | cancer staging | - |
dc.subject | human | - |
dc.subject | hypopharynx | - |
dc.subject | hypopharynx tumor | - |
dc.subject | pathology | - |
dc.title | Surgical treatment of advanced staged hypopharyngeal cancer | - |
dc.type | Article | - |
dc.identifier.email | Wei, WI: hrmswwi@hkucc.hku.hk | - |
dc.identifier.email | Chan, JYW: jywchan1@HKUCC-COM.hku.hk | - |
dc.identifier.authority | Wei, WI=rp00323 | - |
dc.identifier.authority | Chan, JYW=rp01314 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1159/000492312 | - |
dc.identifier.pmid | 30943506 | - |
dc.identifier.scopus | eid_2-s2.0-85061749509 | - |
dc.identifier.hkuros | 299862 | - |
dc.identifier.volume | 83 | - |
dc.identifier.spage | 66 | - |
dc.identifier.epage | 75 | - |
dc.publisher.place | Switzerland | - |
dc.identifier.issnl | 0065-3071 | - |