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Article: Immunohistochemical characterization of stem cell and differentiation markers of the dental pulp of human natal teeth

TitleImmunohistochemical characterization of stem cell and differentiation markers of the dental pulp of human natal teeth
Authors
KeywordsCD44
dental pulp stem cell (DPSC)
desmin
immunohistochemical expression
natal teeth
Issue Date2018
PublisherFuture Science Ltd. The Journal's web site is located at http://www.future-science.com/loi/fso
Citation
Future Science OA, 2018, v. 4 n. 10, p. article no. FSO342 How to Cite?
AbstractAim: Dental pulp stem cells, which are primarily derived from the pulp tissues of human teeth, have rarely been obtained from natal teeth. This study investigated the stem cell and differentiation markers of the dental pulp of natal teeth using immunohistochemistry. Materials & methods: The pulp tissue from extracted natal teeth (n = 2) of a 20-day-old healthy male was examined for immunohistochemical expression of stem cell (Oct-4 and SOX 2) and differentiation markers (Nestin, CD 44, desmin, osteopontin and Ki- 67). Results: The pulp tissue of the natal teeth expressed immunopositivity for nestin, CD 44 and SOX2. Conclusion: Natal teeth, if preserved properly, could serve as sources of dental pulp stem cells that are an improvement on deciduous teeth.
Persistent Identifierhttp://hdl.handle.net/10722/272800
ISSN
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorShetty, H-
dc.contributor.authorKakade, A-
dc.contributor.authorShetty, S-
dc.contributor.authorNeelakantan, P-
dc.contributor.authorNagar, S-
dc.contributor.authorDesai, RS-
dc.contributor.authorBeri, K-
dc.date.accessioned2019-08-06T09:16:48Z-
dc.date.available2019-08-06T09:16:48Z-
dc.date.issued2018-
dc.identifier.citationFuture Science OA, 2018, v. 4 n. 10, p. article no. FSO342-
dc.identifier.issn2056-5623-
dc.identifier.urihttp://hdl.handle.net/10722/272800-
dc.description.abstractAim: Dental pulp stem cells, which are primarily derived from the pulp tissues of human teeth, have rarely been obtained from natal teeth. This study investigated the stem cell and differentiation markers of the dental pulp of natal teeth using immunohistochemistry. Materials & methods: The pulp tissue from extracted natal teeth (n = 2) of a 20-day-old healthy male was examined for immunohistochemical expression of stem cell (Oct-4 and SOX 2) and differentiation markers (Nestin, CD 44, desmin, osteopontin and Ki- 67). Results: The pulp tissue of the natal teeth expressed immunopositivity for nestin, CD 44 and SOX2. Conclusion: Natal teeth, if preserved properly, could serve as sources of dental pulp stem cells that are an improvement on deciduous teeth.-
dc.languageeng-
dc.publisherFuture Science Ltd. The Journal's web site is located at http://www.future-science.com/loi/fso-
dc.relation.ispartofFuture Science OA-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectCD44-
dc.subjectdental pulp stem cell (DPSC)-
dc.subjectdesmin-
dc.subjectimmunohistochemical expression-
dc.subjectnatal teeth-
dc.titleImmunohistochemical characterization of stem cell and differentiation markers of the dental pulp of human natal teeth-
dc.typeArticle-
dc.identifier.emailNeelakantan, P: prasanna@hku.hk-
dc.identifier.authorityNeelakantan, P=rp02214-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.4155/fsoa-2018-0062-
dc.identifier.pmid30450229-
dc.identifier.pmcidPMC6234461-
dc.identifier.scopuseid_2-s2.0-85069008710-
dc.identifier.hkuros299736-
dc.identifier.volume4-
dc.identifier.issue10-
dc.identifier.spagearticle no. FSO342-
dc.identifier.epagearticle no. FSO342-
dc.publisher.placeUnited Kingdom-

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