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- Publisher Website: 10.4155/fsoa-2018-0062
- Scopus: eid_2-s2.0-85069008710
- PMID: 30450229
- WOS: WOS:000454655300003
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Article: Immunohistochemical characterization of stem cell and differentiation markers of the dental pulp of human natal teeth
Title | Immunohistochemical characterization of stem cell and differentiation markers of the dental pulp of human natal teeth |
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Authors | |
Keywords | CD44 dental pulp stem cell (DPSC) desmin immunohistochemical expression natal teeth |
Issue Date | 2018 |
Publisher | Future Science Ltd. The Journal's web site is located at http://www.future-science.com/loi/fso |
Citation | Future Science OA, 2018, v. 4 n. 10, p. article no. FSO342 How to Cite? |
Abstract | Aim: Dental pulp stem cells, which are primarily derived from the pulp tissues of human teeth, have rarely been obtained from natal teeth. This study investigated the stem cell and differentiation markers of the dental pulp of natal teeth using immunohistochemistry. Materials & methods: The pulp tissue from extracted natal teeth (n = 2) of a 20-day-old healthy male was examined for immunohistochemical expression of stem cell (Oct-4 and SOX 2) and differentiation markers (Nestin, CD 44, desmin, osteopontin and Ki- 67). Results: The pulp tissue of the natal teeth expressed immunopositivity for nestin, CD 44 and SOX2. Conclusion: Natal teeth, if preserved properly, could serve as sources of dental pulp stem cells that are an improvement on deciduous teeth. |
Persistent Identifier | http://hdl.handle.net/10722/272800 |
ISSN | 2020 SCImago Journal Rankings: 0.825 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Shetty, H | - |
dc.contributor.author | Kakade, A | - |
dc.contributor.author | Shetty, S | - |
dc.contributor.author | Neelakantan, P | - |
dc.contributor.author | Nagar, S | - |
dc.contributor.author | Desai, RS | - |
dc.contributor.author | Beri, K | - |
dc.date.accessioned | 2019-08-06T09:16:48Z | - |
dc.date.available | 2019-08-06T09:16:48Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Future Science OA, 2018, v. 4 n. 10, p. article no. FSO342 | - |
dc.identifier.issn | 2056-5623 | - |
dc.identifier.uri | http://hdl.handle.net/10722/272800 | - |
dc.description.abstract | Aim: Dental pulp stem cells, which are primarily derived from the pulp tissues of human teeth, have rarely been obtained from natal teeth. This study investigated the stem cell and differentiation markers of the dental pulp of natal teeth using immunohistochemistry. Materials & methods: The pulp tissue from extracted natal teeth (n = 2) of a 20-day-old healthy male was examined for immunohistochemical expression of stem cell (Oct-4 and SOX 2) and differentiation markers (Nestin, CD 44, desmin, osteopontin and Ki- 67). Results: The pulp tissue of the natal teeth expressed immunopositivity for nestin, CD 44 and SOX2. Conclusion: Natal teeth, if preserved properly, could serve as sources of dental pulp stem cells that are an improvement on deciduous teeth. | - |
dc.language | eng | - |
dc.publisher | Future Science Ltd. The Journal's web site is located at http://www.future-science.com/loi/fso | - |
dc.relation.ispartof | Future Science OA | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | CD44 | - |
dc.subject | dental pulp stem cell (DPSC) | - |
dc.subject | desmin | - |
dc.subject | immunohistochemical expression | - |
dc.subject | natal teeth | - |
dc.title | Immunohistochemical characterization of stem cell and differentiation markers of the dental pulp of human natal teeth | - |
dc.type | Article | - |
dc.identifier.email | Neelakantan, P: prasanna@hku.hk | - |
dc.identifier.authority | Neelakantan, P=rp02214 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.4155/fsoa-2018-0062 | - |
dc.identifier.pmid | 30450229 | - |
dc.identifier.pmcid | PMC6234461 | - |
dc.identifier.scopus | eid_2-s2.0-85069008710 | - |
dc.identifier.hkuros | 299736 | - |
dc.identifier.volume | 4 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | article no. FSO342 | - |
dc.identifier.epage | article no. FSO342 | - |
dc.identifier.isi | WOS:000454655300003 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 2056-5623 | - |