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Article: A pollution gradient contributes to the taxonomic, functional, and resistome diversity of microbial communities in marine sediments

TitleA pollution gradient contributes to the taxonomic, functional, and resistome diversity of microbial communities in marine sediments
Authors
KeywordsAntibiotic resistance genes
Marine sediments
Metagenomics
Pollution concentration
Issue Date2019
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.microbiomejournal.com/
Citation
Microbiome, 2019, v. 7, article no. 104 How to Cite?
AbstractBackground: Coastal marine environments are one of the most productive ecosystems on Earth. However, anthropogenic impacts exert significant pressure on coastal marine biodiversity, contributing to functional shifts in microbial communities and human health risk factors. However, relatively little is known about the impact of eutrophication—human-derived nutrient pollution—on the marine microbial biosphere. Results: Here, we tested the hypothesis that benthic microbial diversity and function varies along a pollution gradient, with a focus on human pathogens and antibiotic resistance genes. Comprehensive metagenomic analysis including taxonomic investigation, functional detection, and ARG annotation revealed that zinc, lead, total volatile solids, and ammonia nitrogen were correlated with microbial diversity and function. We propose several microbes, including Planctomycetes and sulfate-reducing microbes as candidates to reflect pollution concentration. Annotation of antibiotic resistance genes showed that the highest abundance of efflux pumps was found at the most polluted site, corroborating the relationship between pollution and human health risk factors. This result suggests that sediments at polluted sites harbor microbes with a higher capacity to reduce intracellular levels of antibiotics, heavy metals, or other environmental contaminants. Conclusions: Our findings suggest a correlation between pollution and the marine sediment microbiome and provide insight into the role of high-turnover microbial communities as well as potential pathogenic organisms as real-time indicators of water quality, with implications for human health and demonstrate the inner functional shifts contributed by the microcommunities.
Persistent Identifierhttp://hdl.handle.net/10722/272498
ISSN
2023 Impact Factor: 13.8
2023 SCImago Journal Rankings: 3.802
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChen, J-
dc.contributor.authorMcIlroy, SE-
dc.contributor.authorArchana, A-
dc.contributor.authorBaker, DM-
dc.contributor.authorPanagiotou, G-
dc.date.accessioned2019-07-20T10:43:27Z-
dc.date.available2019-07-20T10:43:27Z-
dc.date.issued2019-
dc.identifier.citationMicrobiome, 2019, v. 7, article no. 104-
dc.identifier.issn2049-2618-
dc.identifier.urihttp://hdl.handle.net/10722/272498-
dc.description.abstractBackground: Coastal marine environments are one of the most productive ecosystems on Earth. However, anthropogenic impacts exert significant pressure on coastal marine biodiversity, contributing to functional shifts in microbial communities and human health risk factors. However, relatively little is known about the impact of eutrophication—human-derived nutrient pollution—on the marine microbial biosphere. Results: Here, we tested the hypothesis that benthic microbial diversity and function varies along a pollution gradient, with a focus on human pathogens and antibiotic resistance genes. Comprehensive metagenomic analysis including taxonomic investigation, functional detection, and ARG annotation revealed that zinc, lead, total volatile solids, and ammonia nitrogen were correlated with microbial diversity and function. We propose several microbes, including Planctomycetes and sulfate-reducing microbes as candidates to reflect pollution concentration. Annotation of antibiotic resistance genes showed that the highest abundance of efflux pumps was found at the most polluted site, corroborating the relationship between pollution and human health risk factors. This result suggests that sediments at polluted sites harbor microbes with a higher capacity to reduce intracellular levels of antibiotics, heavy metals, or other environmental contaminants. Conclusions: Our findings suggest a correlation between pollution and the marine sediment microbiome and provide insight into the role of high-turnover microbial communities as well as potential pathogenic organisms as real-time indicators of water quality, with implications for human health and demonstrate the inner functional shifts contributed by the microcommunities.-
dc.languageeng-
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.microbiomejournal.com/-
dc.relation.ispartofMicrobiome-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAntibiotic resistance genes-
dc.subjectMarine sediments-
dc.subjectMetagenomics-
dc.subjectPollution concentration-
dc.titleA pollution gradient contributes to the taxonomic, functional, and resistome diversity of microbial communities in marine sediments-
dc.typeArticle-
dc.identifier.emailMcIlroy, SE: smcilroy@hku.hk-
dc.identifier.emailBaker, DM: dmbaker@hku.hk-
dc.identifier.emailPanagiotou, G: gipa@hku.hk-
dc.identifier.authorityBaker, DM=rp01712-
dc.identifier.authorityPanagiotou, G=rp01725-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1186/s40168-019-0714-6-
dc.identifier.pmid31307536-
dc.identifier.pmcidPMC6632204-
dc.identifier.scopuseid_2-s2.0-85069041166-
dc.identifier.hkuros299318-
dc.identifier.volume7-
dc.identifier.spagearticle no. 104-
dc.identifier.epagearticle no. 104-
dc.identifier.isiWOS:000475700500001-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl2049-2618-

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