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- Publisher Website: 10.1039/C8CS00532J
- Scopus: eid_2-s2.0-85057108684
- PMID: 30394457
- WOS: WOS:000451657800013
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Article: Application of (4+3) cycloaddition strategies in the synthesis of natural products
Title | Application of (4+3) cycloaddition strategies in the synthesis of natural products |
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Authors | |
Issue Date | 2018 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cs/index.asp |
Citation | Chemical Society Reviews, 2018, v. 47 n. 23, p. 8881-8924 How to Cite? |
Abstract | (4+3) Cycloadditions have been widely applied in synthesis, and in this review article, we summarize some of the more recent applications, including formal (4+3) cycloadditions, in the synthesis of natural products. Many of these natural product target frameworks have cycloheptane subunits, for which the (4+3) cycloaddition is a convergent strategy for their assembly. Some natural product targets do not possess seven membered rings, and their syntheses have exploited the functional group endowed (4+3) cycloadducts resulting from these reactions, highlighting the utility of this methodology for the synthesis of a range of complex molecules. |
Persistent Identifier | http://hdl.handle.net/10722/272134 |
ISSN | 2023 Impact Factor: 40.4 2023 SCImago Journal Rankings: 12.511 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Yin, Z | - |
dc.contributor.author | HE, Y | - |
dc.contributor.author | Chiu, P | - |
dc.date.accessioned | 2019-07-20T10:36:20Z | - |
dc.date.available | 2019-07-20T10:36:20Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Chemical Society Reviews, 2018, v. 47 n. 23, p. 8881-8924 | - |
dc.identifier.issn | 0306-0012 | - |
dc.identifier.uri | http://hdl.handle.net/10722/272134 | - |
dc.description.abstract | (4+3) Cycloadditions have been widely applied in synthesis, and in this review article, we summarize some of the more recent applications, including formal (4+3) cycloadditions, in the synthesis of natural products. Many of these natural product target frameworks have cycloheptane subunits, for which the (4+3) cycloaddition is a convergent strategy for their assembly. Some natural product targets do not possess seven membered rings, and their syntheses have exploited the functional group endowed (4+3) cycloadducts resulting from these reactions, highlighting the utility of this methodology for the synthesis of a range of complex molecules. | - |
dc.language | eng | - |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cs/index.asp | - |
dc.relation.ispartof | Chemical Society Reviews | - |
dc.subject.mesh | Biological Products | - |
dc.subject.mesh | Cycloaddition Reaction | - |
dc.subject.mesh | Cycloheptanes | - |
dc.subject.mesh | Molecular Structure | - |
dc.title | Application of (4+3) cycloaddition strategies in the synthesis of natural products | - |
dc.type | Article | - |
dc.identifier.email | Yin, Z: zsyin@hku.hk | - |
dc.identifier.email | Chiu, P: pchiu@hku.hk | - |
dc.identifier.authority | Chiu, P=rp00680 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1039/C8CS00532J | - |
dc.identifier.pmid | 30394457 | - |
dc.identifier.scopus | eid_2-s2.0-85057108684 | - |
dc.identifier.hkuros | 298417 | - |
dc.identifier.volume | 47 | - |
dc.identifier.issue | 23 | - |
dc.identifier.spage | 8881 | - |
dc.identifier.epage | 8924 | - |
dc.identifier.isi | WOS:000451657800013 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0306-0012 | - |