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Article: Children and adolescents with marginal zone lymphoma have an excellent prognosis with limited chemotherapy or a watch-and-wait strategy after complete resection

TitleChildren and adolescents with marginal zone lymphoma have an excellent prognosis with limited chemotherapy or a watch-and-wait strategy after complete resection
Authors
KeywordsComplete resection
Marginal zone lymphoma
Outcome
Watch-and-wait
Issue Date2018
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1545-5017/
Citation
Pediatric Blood & Cancer, 2018, v. 65 n. 4, article no. e26932 How to Cite?
AbstractData on management of pediatric marginal zone lymphoma (MZL) are scarce. This retrospective study assessed characteristics and outcome in 66 patients who were <18 years old. Forty-four (67%) had an extranodal MZL (EMZL), 21 (32%) a nodal MZL (NMZL), and one patient a splenic MZL. Thirty-three patients (50%) received a variable combination of adjuvant chemotherapy/immunotherapy/radiotherapy, while the remainder, including 20 of 21 with NMZL, entered an active observation period. Overall survival was excellent (98 ± 2%), although 11 patients relapsed (17%; NMZL, n = 1; EMZL, n = 10), seven after any therapy and four after complete resection only. In conclusion, outcome of NZML, in particular, seems to be excellent after (in)complete resection and observation only.
Persistent Identifierhttp://hdl.handle.net/10722/263391
ISSN
2021 Impact Factor: 3.838
2020 SCImago Journal Rankings: 1.116
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorRonceray, L-
dc.contributor.authorAbla, O-
dc.contributor.authorBarzilai-Birenboim, S-
dc.contributor.authorBomken , S-
dc.contributor.authorChiang, AKS-
dc.contributor.authorJazbec, J-
dc.contributor.authorKabickova, E-
dc.contributor.authorLazic, J-
dc.contributor.authorBeishuizen, A-
dc.contributor.authorMellgren, K-
dc.contributor.authorTanaka, FI-
dc.contributor.authorPillon, MM-
dc.contributor.authorDevalck, CN-
dc.contributor.authorGouttenoire, MO-
dc.contributor.authorMakarova, OP-
dc.contributor.authorBurkhardt, BP-
dc.contributor.authorAttarbaschi, AA-
dc.date.accessioned2018-10-22T07:38:10Z-
dc.date.available2018-10-22T07:38:10Z-
dc.date.issued2018-
dc.identifier.citationPediatric Blood & Cancer, 2018, v. 65 n. 4, article no. e26932-
dc.identifier.issn1545-5009-
dc.identifier.urihttp://hdl.handle.net/10722/263391-
dc.description.abstractData on management of pediatric marginal zone lymphoma (MZL) are scarce. This retrospective study assessed characteristics and outcome in 66 patients who were <18 years old. Forty-four (67%) had an extranodal MZL (EMZL), 21 (32%) a nodal MZL (NMZL), and one patient a splenic MZL. Thirty-three patients (50%) received a variable combination of adjuvant chemotherapy/immunotherapy/radiotherapy, while the remainder, including 20 of 21 with NMZL, entered an active observation period. Overall survival was excellent (98 ± 2%), although 11 patients relapsed (17%; NMZL, n = 1; EMZL, n = 10), seven after any therapy and four after complete resection only. In conclusion, outcome of NZML, in particular, seems to be excellent after (in)complete resection and observation only.-
dc.languageeng-
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1545-5017/-
dc.relation.ispartofPediatric Blood & Cancer-
dc.subjectComplete resection-
dc.subjectMarginal zone lymphoma-
dc.subjectOutcome-
dc.subjectWatch-and-wait-
dc.titleChildren and adolescents with marginal zone lymphoma have an excellent prognosis with limited chemotherapy or a watch-and-wait strategy after complete resection-
dc.typeArticle-
dc.identifier.emailChiang, AKS: chiangak@hku.hk-
dc.identifier.authorityChiang, AKS=rp00403-
dc.description.naturepostprint-
dc.identifier.doi10.1002/pbc.26932-
dc.identifier.scopuseid_2-s2.0-85039761187-
dc.identifier.hkuros295015-
dc.identifier.volume65-
dc.identifier.issue4-
dc.identifier.spagearticle no. e26932-
dc.identifier.epagearticle no. e26932-
dc.identifier.isiWOS:000425642100030-
dc.publisher.placeUnited States-
dc.identifier.issnl1545-5009-

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