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Article: Copper-based reactions in analyte-responsive fluorescent probes for biological applications

TitleCopper-based reactions in analyte-responsive fluorescent probes for biological applications
Authors
Issue Date2017
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jinorgbio
Citation
Journal of Inorganic Biochemistry, 2017, v. 177, p. 300-312 How to Cite?
AbstractCopper chemistry has been capitalized on in a wide spectrum of biological events. The central importance of copper in biology lies in the diverse chemical reactivity of the redox-active transition metal ranging from electron transfer, small molecule binding and activation, to catalysis. In addition to its many different roles in natural biological systems, the diverse chemical reactivity of copper also represents a rich opportunity and resource to develop synthetic bioanalytical tools for the study of biologically important species and molecules. In this mini-review, fluorescent probes featuring a specific copper-based chemical reaction to selectively detect a biologically relevant analyte will be discussed. In particular, fluorescent probes for sensing labile copper ions, amino acids and small reactive species will be highlighted. The chemical principles, advantages and limitations of the different types of copper-mediated chemical reactions in these fluorescent probes will be emphasized.
Persistent Identifierhttp://hdl.handle.net/10722/252128
ISSN
2021 Impact Factor: 4.336
2020 SCImago Journal Rankings: 0.695

 

DC FieldValueLanguage
dc.contributor.authorAu Yeung, HY-
dc.contributor.authorChan, CYK-
dc.contributor.authorTong, KY-
dc.contributor.authorYu, ZH-
dc.date.accessioned2018-04-11T02:11:11Z-
dc.date.available2018-04-11T02:11:11Z-
dc.date.issued2017-
dc.identifier.citationJournal of Inorganic Biochemistry, 2017, v. 177, p. 300-312-
dc.identifier.issn0162-0134-
dc.identifier.urihttp://hdl.handle.net/10722/252128-
dc.description.abstractCopper chemistry has been capitalized on in a wide spectrum of biological events. The central importance of copper in biology lies in the diverse chemical reactivity of the redox-active transition metal ranging from electron transfer, small molecule binding and activation, to catalysis. In addition to its many different roles in natural biological systems, the diverse chemical reactivity of copper also represents a rich opportunity and resource to develop synthetic bioanalytical tools for the study of biologically important species and molecules. In this mini-review, fluorescent probes featuring a specific copper-based chemical reaction to selectively detect a biologically relevant analyte will be discussed. In particular, fluorescent probes for sensing labile copper ions, amino acids and small reactive species will be highlighted. The chemical principles, advantages and limitations of the different types of copper-mediated chemical reactions in these fluorescent probes will be emphasized.-
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jinorgbio-
dc.relation.ispartofJournal of Inorganic Biochemistry-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleCopper-based reactions in analyte-responsive fluorescent probes for biological applications-
dc.typeArticle-
dc.identifier.emailAu Yeung, HY: hoyuay@hku.hk-
dc.identifier.emailChan, CYK: kchych@hku.hk-
dc.identifier.authorityAu Yeung, HY=rp01819-
dc.description.naturepostprint-
dc.identifier.doi10.1016/j.jinorgbio.2017.07.001-
dc.identifier.scopuseid_2-s2.0-85024092682-
dc.identifier.hkuros284716-
dc.identifier.volume177-
dc.identifier.spage300-
dc.identifier.epage312-
dc.publisher.placeUnited States-
dc.identifier.issnl0162-0134-

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