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Book Chapter: LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples

TitleLC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples
Authors
Lee, YYLee, CYJ
KeywordsLipid peroxidation products
Isoprostanes
Isofurans
Liquid chromatography-tandem mass spectrometry
Issue Date2018
PublisherHumana Press.
Citation
LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples. In Giera, M (Eds.), Clinical Metabolomics, v. 1730, p. 83-92. New York, NY: Humana Press, 2018 How to Cite?
DOI: http://dx.doi.org/10.1007/978-1-4939-7592-1_6
AbstractOxygenated lipid products of non-cyclooxygenase derivatives, namely, prostanoids such as, isoprostanes and isofurans, are formed in vivo through lipid autoxidation. Insofar it has been marked as novel biomarkers of oxidative stress in the biological systems. Elevations of these oxidized products are associated with several diseases. This chapter describes the preparation and measurement of the products, including newly identified F2-dihomo-isoprostanes and dihomo-isofurans, from plasma and tissue samples using the liquid chromatography-tandem mass spectrometry approach.
Persistent Identifierhttp://hdl.handle.net/10722/251550
ISBN
978-1-4939-7591-4
ISSN
1064-3745
2020 SCImago Journal Rankings: 0.711

 

DC FieldValueLanguage
dc.contributor.authorLee, YY-
dc.contributor.authorLee, CYJ-
dc.date.accessioned2018-03-01T03:41:02Z-
dc.date.available2018-03-01T03:41:02Z-
dc.date.issued2018-
dc.identifier.citationLC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples. In Giera, M (Eds.), Clinical Metabolomics, v. 1730, p. 83-92. New York, NY: Humana Press, 2018-
dc.identifier.isbn978-1-4939-7591-4-
dc.identifier.issn1064-3745-
dc.identifier.urihttp://hdl.handle.net/10722/251550-
dc.description.abstractOxygenated lipid products of non-cyclooxygenase derivatives, namely, prostanoids such as, isoprostanes and isofurans, are formed in vivo through lipid autoxidation. Insofar it has been marked as novel biomarkers of oxidative stress in the biological systems. Elevations of these oxidized products are associated with several diseases. This chapter describes the preparation and measurement of the products, including newly identified F2-dihomo-isoprostanes and dihomo-isofurans, from plasma and tissue samples using the liquid chromatography-tandem mass spectrometry approach.-
dc.languageeng-
dc.publisherHumana Press.-
dc.relation.ispartofClinical Metabolomics-
dc.subjectLipid peroxidation products-
dc.subjectIsoprostanes-
dc.subjectIsofurans-
dc.subjectLiquid chromatography-tandem mass spectrometry-
dc.titleLC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples-
dc.typeBook_Chapter-
dc.identifier.emailLee, CYJ: jettylee@hku.hk-
dc.identifier.authorityLee, CYJ=rp01511-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/978-1-4939-7592-1_6-
dc.identifier.scopuseid_2-s2.0-85041119136-
dc.identifier.hkuros284243-
dc.identifier.volume1730-
dc.identifier.spage83-
dc.identifier.epage92-
dc.identifier.eissn1940-6029-
dc.publisher.placeNew York, NY-
dc.identifier.issnl1064-3745-

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