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Book Chapter: LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples
Title | LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples |
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Authors | |
Keywords | Lipid peroxidation products Isoprostanes Isofurans Liquid chromatography-tandem mass spectrometry |
Issue Date | 2018 |
Publisher | Humana Press. |
Citation | LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples. In Giera, M (Eds.), Clinical Metabolomics, v. 1730, p. 83-92. New York, NY: Humana Press, 2018 How to Cite? |
Abstract | Oxygenated lipid products of non-cyclooxygenase derivatives, namely, prostanoids such as, isoprostanes and isofurans, are formed in vivo through lipid autoxidation. Insofar it has been marked as novel biomarkers of oxidative stress in the biological systems. Elevations of these oxidized products are associated with several diseases. This chapter describes the preparation and measurement of the products, including newly identified F2-dihomo-isoprostanes and dihomo-isofurans, from plasma and tissue samples using the liquid chromatography-tandem mass spectrometry approach. |
Persistent Identifier | http://hdl.handle.net/10722/251550 |
ISBN | |
ISSN | 2023 SCImago Journal Rankings: 0.399 |
DC Field | Value | Language |
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dc.contributor.author | Lee, YY | - |
dc.contributor.author | Lee, CYJ | - |
dc.date.accessioned | 2018-03-01T03:41:02Z | - |
dc.date.available | 2018-03-01T03:41:02Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples. In Giera, M (Eds.), Clinical Metabolomics, v. 1730, p. 83-92. New York, NY: Humana Press, 2018 | - |
dc.identifier.isbn | 978-1-4939-7591-4 | - |
dc.identifier.issn | 1064-3745 | - |
dc.identifier.uri | http://hdl.handle.net/10722/251550 | - |
dc.description.abstract | Oxygenated lipid products of non-cyclooxygenase derivatives, namely, prostanoids such as, isoprostanes and isofurans, are formed in vivo through lipid autoxidation. Insofar it has been marked as novel biomarkers of oxidative stress in the biological systems. Elevations of these oxidized products are associated with several diseases. This chapter describes the preparation and measurement of the products, including newly identified F2-dihomo-isoprostanes and dihomo-isofurans, from plasma and tissue samples using the liquid chromatography-tandem mass spectrometry approach. | - |
dc.language | eng | - |
dc.publisher | Humana Press. | - |
dc.relation.ispartof | Clinical Metabolomics | - |
dc.subject | Lipid peroxidation products | - |
dc.subject | Isoprostanes | - |
dc.subject | Isofurans | - |
dc.subject | Liquid chromatography-tandem mass spectrometry | - |
dc.title | LC-MS/MS Analysis of Lipid Oxidation Products in Blood and Tissue Samples | - |
dc.type | Book_Chapter | - |
dc.identifier.email | Lee, CYJ: jettylee@hku.hk | - |
dc.identifier.authority | Lee, CYJ=rp01511 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1007/978-1-4939-7592-1_6 | - |
dc.identifier.scopus | eid_2-s2.0-85041119136 | - |
dc.identifier.hkuros | 284243 | - |
dc.identifier.volume | 1730 | - |
dc.identifier.spage | 83 | - |
dc.identifier.epage | 92 | - |
dc.identifier.eissn | 1940-6029 | - |
dc.publisher.place | New York, NY | - |
dc.identifier.issnl | 1064-3745 | - |