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Conference Paper: Histogram analysis of intravoxel incoherent motion parameters in assessing tumour diffusion and perfusion heterogeneity in cervical cancer before and after chemoradiotherapy

TitleHistogram analysis of intravoxel incoherent motion parameters in assessing tumour diffusion and perfusion heterogeneity in cervical cancer before and after chemoradiotherapy
Authors
Issue Date2017
PublisherInternational Society for Magnetic Resonance in Medicine (ISMRM).
Citation
The International Society for Magnetic Resonance in Medicine (ISMRM) 25th Annual Meeting & Exhibition, Honolulu, HI, 22-27 April 2017 How to Cite?
AbstractHistogram analysis of intravoxel incoherent motion (IVIM) diffusion-weighted MRI (DWI) could be a promising quantitative approach in assessing tumour heterogeneity. We retrospectively studied twenty-five patients with cervical cancer who had paired IVIM MRI examinations before and at week-4 of chemoradiotherapy treatment (CRT). We observed histogram skewness and kurtosis significantly decreased while mean and all percentiles significantly increased in apparent diffusion coefficient (ADC), true diffusion coefficient (D) and perfusion fraction (f) following treatment. Furthermore, these significant differences were not correlated with a change in primary tumour volume (PTV) following treatment.
Persistent Identifierhttp://hdl.handle.net/10722/245515

 

DC FieldValueLanguage
dc.contributor.authorPerucho, JAU-
dc.contributor.authorLee, EYP-
dc.contributor.authorChan, WCL-
dc.contributor.authorGong, N-
dc.contributor.authorChan, Q-
dc.date.accessioned2017-09-18T02:12:04Z-
dc.date.available2017-09-18T02:12:04Z-
dc.date.issued2017-
dc.identifier.citationThe International Society for Magnetic Resonance in Medicine (ISMRM) 25th Annual Meeting & Exhibition, Honolulu, HI, 22-27 April 2017-
dc.identifier.urihttp://hdl.handle.net/10722/245515-
dc.description.abstractHistogram analysis of intravoxel incoherent motion (IVIM) diffusion-weighted MRI (DWI) could be a promising quantitative approach in assessing tumour heterogeneity. We retrospectively studied twenty-five patients with cervical cancer who had paired IVIM MRI examinations before and at week-4 of chemoradiotherapy treatment (CRT). We observed histogram skewness and kurtosis significantly decreased while mean and all percentiles significantly increased in apparent diffusion coefficient (ADC), true diffusion coefficient (D) and perfusion fraction (f) following treatment. Furthermore, these significant differences were not correlated with a change in primary tumour volume (PTV) following treatment.-
dc.languageeng-
dc.publisherInternational Society for Magnetic Resonance in Medicine (ISMRM). -
dc.relation.ispartofThe International Society for Magnetic Resonance in Medicine (ISMRM) Annual Meeting & Exhibition-
dc.titleHistogram analysis of intravoxel incoherent motion parameters in assessing tumour diffusion and perfusion heterogeneity in cervical cancer before and after chemoradiotherapy-
dc.typeConference_Paper-
dc.identifier.emailLee, EYP: eyplee77@hku.hk-
dc.identifier.authorityLee, EYP=rp01456-
dc.identifier.hkuros278822-
dc.publisher.placeHonolulu, HI-

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