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Conference Paper: Prevention and treatment of oral mucositis caused by chemo- and radiotherapy in head and neck cancer patient
Title | Prevention and treatment of oral mucositis caused by chemo- and radiotherapy in head and neck cancer patient |
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Authors | |
Issue Date | 2017 |
Publisher | Churchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijom |
Citation | The 23rd International Conference on Oral and Maxillofacial Surgery (ICOMS 2017), Hong Kong, 31 March - 3 April 2017. In International Journal of Oral and Maxillofacial Surgery, 2017, v. 46 n. Suppl. 1, p. 144 How to Cite? |
Abstract | Background: Oral mucositis is one of the most common complications of chemo- and radiotherapy for treatment of cancer. This condition is prevalent in up to 40% of individuals who are undergoing cancer therapy. Adverse reactions include but not limited to malnutrition, prolonged hospital stays, increased risk of infection and negative impact in quality of life.
Objectives: The purpose of this study was to examine and compare current evidence on treatment modalities for oral mucositis by performing a systemic review. A literature search identified for randomised controlled trials (RCTs) for preventive and therapeutic intervention of oral mucositis in head and neck cancer patients undergoing radiation therapy and/or chemotherapy.
Methods: This systematic review followed the Cochrane Collaboration Handbook of Interventions Systematic Reviews and the PRISMA statement checklist and flowchart. A sensitive search protocol was developed to retrieve RCTs published in peer-reviewed journals from 1980 to September 2016 using MEDLINE via PubMed (1970–September 2016), EMBASE via Ovid (1980–September 2016).
Search queries included MeSH terms for: oral mucositis; chemotherapy; radiotherapy; head and neck cancer.
Identification of randomised trials was done according to CONSORT statement. 11 articles on laser therapy; 10 articles on topical treatment and 8 articles on medical therapy were included into the final review.
Findings and Conclusion: The outcome of this study has identified effective medical and surgical interventions for prevention and treatment of oral mucositis. Further trials will be necessary to identify a superior modality or protocol as a standard therapy of radio- and chemotherapy-induced oral mucositis.
Copyright © 2017 Published by Elsevier Ltd. |
Description | ICOMS 2017 Abstracts Only Supplement |
Persistent Identifier | http://hdl.handle.net/10722/245487 |
ISSN | 2023 Impact Factor: 2.2 2023 SCImago Journal Rankings: 0.875 |
DC Field | Value | Language |
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dc.contributor.author | Ho, JKH | - |
dc.contributor.author | Choi, WWS | - |
dc.date.accessioned | 2017-09-18T02:11:35Z | - |
dc.date.available | 2017-09-18T02:11:35Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | The 23rd International Conference on Oral and Maxillofacial Surgery (ICOMS 2017), Hong Kong, 31 March - 3 April 2017. In International Journal of Oral and Maxillofacial Surgery, 2017, v. 46 n. Suppl. 1, p. 144 | - |
dc.identifier.issn | 0901-5027 | - |
dc.identifier.uri | http://hdl.handle.net/10722/245487 | - |
dc.description | ICOMS 2017 Abstracts Only Supplement | - |
dc.description.abstract | Background: Oral mucositis is one of the most common complications of chemo- and radiotherapy for treatment of cancer. This condition is prevalent in up to 40% of individuals who are undergoing cancer therapy. Adverse reactions include but not limited to malnutrition, prolonged hospital stays, increased risk of infection and negative impact in quality of life. Objectives: The purpose of this study was to examine and compare current evidence on treatment modalities for oral mucositis by performing a systemic review. A literature search identified for randomised controlled trials (RCTs) for preventive and therapeutic intervention of oral mucositis in head and neck cancer patients undergoing radiation therapy and/or chemotherapy. Methods: This systematic review followed the Cochrane Collaboration Handbook of Interventions Systematic Reviews and the PRISMA statement checklist and flowchart. A sensitive search protocol was developed to retrieve RCTs published in peer-reviewed journals from 1980 to September 2016 using MEDLINE via PubMed (1970–September 2016), EMBASE via Ovid (1980–September 2016). Search queries included MeSH terms for: oral mucositis; chemotherapy; radiotherapy; head and neck cancer. Identification of randomised trials was done according to CONSORT statement. 11 articles on laser therapy; 10 articles on topical treatment and 8 articles on medical therapy were included into the final review. Findings and Conclusion: The outcome of this study has identified effective medical and surgical interventions for prevention and treatment of oral mucositis. Further trials will be necessary to identify a superior modality or protocol as a standard therapy of radio- and chemotherapy-induced oral mucositis. Copyright © 2017 Published by Elsevier Ltd. | - |
dc.language | eng | - |
dc.publisher | Churchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijom | - |
dc.relation.ispartof | International Journal of Oral and Maxillofacial Surgery | - |
dc.title | Prevention and treatment of oral mucositis caused by chemo- and radiotherapy in head and neck cancer patient | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Choi, WWS: drwchoi@hku.hk | - |
dc.identifier.authority | Choi, WWS=rp01521 | - |
dc.identifier.doi | 10.1016/j.ijom.2017.02.497 | - |
dc.identifier.hkuros | 279140 | - |
dc.identifier.volume | 46 | - |
dc.identifier.issue | Suppl. 1 | - |
dc.identifier.spage | 144 | - |
dc.identifier.epage | 144 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 0901-5027 | - |