Impact of interventions on influenza A(H7N9) virus activity in live poultry markets

Abstract

H7N9 virus emerged in Eastern China in March 2013, which led to >550 human cases and >200 deaths in 2 years. Live poultry markets (LPMs) are considered as a major source of human H7N9 infections. In late 2013, the virus had spread to the southern provinces including Guangdong. Its provincial capital Guangzhou, detected its first local H7N9 human case in mid-January 2014 and reaching 10 cases in a month. As a response, Guangzhou government announced a two-week city-wide market closure, banning trading and storing of live poultry. Guangzhou Center for Disease Control and Prevention took this opportunity to establish enhanced surveillance on top of the existing routine LPM surveillance, to assess the impact of such on H7N9 viral isolation and survival. Objective : This study assessed the effect of disinfection and closing live poultry markets in China on avian influenza A(H7N9) virus detection and viability in a natural setting. We characterized virus detection at different sampling sites to assess exposure risk to the general public and live poultry traders.