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Article: Identification Q1 of Annexin A2 as a target protein for plant alkaloid matrine

TitleIdentification Q1 of Annexin A2 as a target protein for plant alkaloid matrine
Authors
Issue Date2017
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2017, v. 53, p. 5020-5023 How to Cite?
AbstractMatrine is a plant alkaloid and a major active component in the Chinese medical herb Sophora flavescens. Matrine has shown potent anti-cancer activities but its molecular target(s) and mechanism are still unknown. Using the photo-affinity labeling approach, for the first time, Annexin A2 was identified as a direct-binding target of matrine in cancer cells.
Persistent Identifierhttp://hdl.handle.net/10722/243007
ISSN
2019 Impact Factor: 5.996
2015 SCImago Journal Rankings: 2.771

 

DC FieldValueLanguage
dc.contributor.authorWang, D-
dc.contributor.authorCao, Y-
dc.contributor.authorZheng, L-
dc.contributor.authorLv, D-
dc.contributor.authorChen, L-
dc.contributor.authorXing, X-
dc.contributor.authorZhu, Z-
dc.contributor.authorLi, X-
dc.contributor.authorChai, Y-
dc.date.accessioned2017-08-25T02:48:38Z-
dc.date.available2017-08-25T02:48:38Z-
dc.date.issued2017-
dc.identifier.citationChemical Communications, 2017, v. 53, p. 5020-5023-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/10722/243007-
dc.description.abstractMatrine is a plant alkaloid and a major active component in the Chinese medical herb Sophora flavescens. Matrine has shown potent anti-cancer activities but its molecular target(s) and mechanism are still unknown. Using the photo-affinity labeling approach, for the first time, Annexin A2 was identified as a direct-binding target of matrine in cancer cells.-
dc.languageeng-
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp-
dc.relation.ispartofChemical Communications-
dc.titleIdentification Q1 of Annexin A2 as a target protein for plant alkaloid matrine-
dc.typeArticle-
dc.identifier.emailLi, X: xiaoyuli@hku.hk-
dc.identifier.authorityLi, X=rp02080-
dc.identifier.doi10.1039/C7CC02227A-
dc.identifier.scopuseid_2-s2.0-85021673341-
dc.identifier.hkuros274705-
dc.identifier.volume53-
dc.identifier.spage5020-
dc.identifier.epage5023-
dc.publisher.placeUnited Kingdom-

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