File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Mechanisms of silver diamine fluoride on arresting caries: a literature review

TitleMechanisms of silver diamine fluoride on arresting caries: a literature review
Authors
KeywordsSilver diamine fluoride
Caries
Mechanism
Review
Issue Date2018
PublisherJohn Wiley & Sons Ltd, co-published with FDI World Dental Federation. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1875-595X
Citation
International Dental Journal, 2018, v. 68 n. 2, p. 67-76 How to Cite?
AbstractObjective: To review the evidence regarding the mechanisms of silver diamine fluoride (SDF) for arresting caries. Methods: A literature search was conducted using the keywords silver diamine fluoride, and its alternative names, in seven databases: PubMed, Embase and Scopus (English); China National Knowledge Infrastructure (Chinese); Bilioteca Virtual em Saude (Portuguese); Biblioteca Virtual en Salud Espana (Spanish); and Ichushi‐Web (Japanese). The titles and abstracts were screened. Full texts were retrieved for publications that studied mechanisms of actions of SDF, including its effects on remineralisation of carious lesions and on cariogenic bacteria. Results: A total of 1,123 publications were identified. Twenty‐nine articles were included and they investigated the effect of SDF on cariogenic bacteria and dental hard tissues. Eleven studies investigated the antibacterial properties of SDF. They found that SDF was bactericidal to cariogenic bacteria, mainly Streptococcus mutans. It inhibited the growth of cariogenic biofilms on teeth. Twenty studies reported the remineralisation of demineralised enamel or dentine by SDF. They found that mineral loss of demineralised enamel and dentine was reduced after SDF treatment. A highly mineralised surface rich in calcium and phosphate was formed on arrested carious lesions. Four studies examined the effect of SDF on dentine collagen. They found that SDF inhibited collagenases (matrix metalloproteinases and cysteine cathepsins) and protected dentine collagen from destruction. Conclusion: SDF is a bactericidal agent and reduces the growth of cariogenic bacteria. It inhibits demineralisation and promotes the remineralisation of demineralised enamel and dentine. It also hampers degradation of the dentine collagen.
Persistent Identifierhttp://hdl.handle.net/10722/242975
ISSN
2020 Impact Factor: 2.512
2020 SCImago Journal Rankings: 0.840
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorZhao, IS-
dc.contributor.authorGao, SS-
dc.contributor.authorHiraishi, N-
dc.contributor.authorBurrow, MF-
dc.contributor.authorDuangthip, D-
dc.contributor.authorMei, ML-
dc.contributor.authorLo, ECM-
dc.contributor.authorChu, CH-
dc.date.accessioned2017-08-25T02:48:09Z-
dc.date.available2017-08-25T02:48:09Z-
dc.date.issued2018-
dc.identifier.citationInternational Dental Journal, 2018, v. 68 n. 2, p. 67-76-
dc.identifier.issn0020-6539-
dc.identifier.urihttp://hdl.handle.net/10722/242975-
dc.description.abstractObjective: To review the evidence regarding the mechanisms of silver diamine fluoride (SDF) for arresting caries. Methods: A literature search was conducted using the keywords silver diamine fluoride, and its alternative names, in seven databases: PubMed, Embase and Scopus (English); China National Knowledge Infrastructure (Chinese); Bilioteca Virtual em Saude (Portuguese); Biblioteca Virtual en Salud Espana (Spanish); and Ichushi‐Web (Japanese). The titles and abstracts were screened. Full texts were retrieved for publications that studied mechanisms of actions of SDF, including its effects on remineralisation of carious lesions and on cariogenic bacteria. Results: A total of 1,123 publications were identified. Twenty‐nine articles were included and they investigated the effect of SDF on cariogenic bacteria and dental hard tissues. Eleven studies investigated the antibacterial properties of SDF. They found that SDF was bactericidal to cariogenic bacteria, mainly Streptococcus mutans. It inhibited the growth of cariogenic biofilms on teeth. Twenty studies reported the remineralisation of demineralised enamel or dentine by SDF. They found that mineral loss of demineralised enamel and dentine was reduced after SDF treatment. A highly mineralised surface rich in calcium and phosphate was formed on arrested carious lesions. Four studies examined the effect of SDF on dentine collagen. They found that SDF inhibited collagenases (matrix metalloproteinases and cysteine cathepsins) and protected dentine collagen from destruction. Conclusion: SDF is a bactericidal agent and reduces the growth of cariogenic bacteria. It inhibits demineralisation and promotes the remineralisation of demineralised enamel and dentine. It also hampers degradation of the dentine collagen.-
dc.languageeng-
dc.publisherJohn Wiley & Sons Ltd, co-published with FDI World Dental Federation. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1875-595X-
dc.relation.ispartofInternational Dental Journal-
dc.rightsThis is the peer reviewed version of the following article: International Dental Journal, 2018, v. 68 n. 2, p. 67-76, which has been published in final form at https://doi.org/10.1111/idj.12320. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.-
dc.subjectSilver diamine fluoride-
dc.subjectCaries-
dc.subjectMechanism-
dc.subjectReview-
dc.titleMechanisms of silver diamine fluoride on arresting caries: a literature review-
dc.typeArticle-
dc.identifier.emailGao, SS: sherryg@hku.hk-
dc.identifier.emailBurrow, MF: mfburr58@hku.hk-
dc.identifier.emailDuangthip, D: dduang@hku.hk-
dc.identifier.emailMei, ML: mei1123@hku.hk-
dc.identifier.emailLo, ECM: edward-lo@hku.hk-
dc.identifier.emailChu, CH: chchu@hku.hk-
dc.identifier.authorityGao, SS=rp02662-
dc.identifier.authorityBurrow, MF=rp01306-
dc.identifier.authorityDuangthip, D=rp02457-
dc.identifier.authorityMei, ML=rp01840-
dc.identifier.authorityLo, ECM=rp00015-
dc.identifier.authorityChu, CH=rp00022-
dc.description.naturepostprint-
dc.identifier.doi10.1111/idj.12320-
dc.identifier.pmid28542863-
dc.identifier.scopuseid_2-s2.0-85019596826-
dc.identifier.hkuros274952-
dc.identifier.volume68-
dc.identifier.issue2-
dc.identifier.spage67-
dc.identifier.epage76-
dc.identifier.isiWOS:000428406800001-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl0020-6539-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats