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Article: Changes in symptom severity in Taiwanese lung cancer patients after gefitinib treatment: A pilot study

TitleChanges in symptom severity in Taiwanese lung cancer patients after gefitinib treatment: A pilot study
Authors
KeywordsNon-small cell lung cancer
Targeted therap
Symptom severity
Symptom interference
Gefitinib treatment
Issue Date2014
Citation
International Journal of Palliative Nursing, 2014, v. 20, n. 3, p. 135-142 How to Cite?
AbstractAim: The purpose of this study was to investigate symptom severity in advanced non-small cell lung cancer patients prior to gefitinib treatment and at 1-, 3- and 6-month intervals after starting treatment. Methodology: Fifty seven patients completed the Taiwanese version of the M.D. Anderson Symptom Inventory. The data were analysed using descriptive statistics, the Friedman non-parametric test, and Pearson correlation coefficients. Results: Symptoms of nausea, difficulty remembering, lack of appetite, sadness, and vomiting increased at 1 month after treatment started, pain and shortness of breath increased at 3 months, and disturbed sleep, drowsiness, and numbness increased after 6 months. Fatigue and dry mouth increased at 3 months after treatment started and then decreased. Only distress decreased throughout the course of treatment. Conclusion: The findings may lead to the development of better clinical guidelines and improved information for patients on when to expect the greatest impact from their symptoms during the course of treatment. © 2014 MA Healthcare Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/241206
ISSN
2023 Impact Factor: 0.7
2023 SCImago Journal Rankings: 0.273
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWang, Shu Yi-
dc.contributor.authorTsai, Chun Ming-
dc.contributor.authorLin, Chia Chin-
dc.date.accessioned2017-05-26T03:37:06Z-
dc.date.available2017-05-26T03:37:06Z-
dc.date.issued2014-
dc.identifier.citationInternational Journal of Palliative Nursing, 2014, v. 20, n. 3, p. 135-142-
dc.identifier.issn1357-6321-
dc.identifier.urihttp://hdl.handle.net/10722/241206-
dc.description.abstractAim: The purpose of this study was to investigate symptom severity in advanced non-small cell lung cancer patients prior to gefitinib treatment and at 1-, 3- and 6-month intervals after starting treatment. Methodology: Fifty seven patients completed the Taiwanese version of the M.D. Anderson Symptom Inventory. The data were analysed using descriptive statistics, the Friedman non-parametric test, and Pearson correlation coefficients. Results: Symptoms of nausea, difficulty remembering, lack of appetite, sadness, and vomiting increased at 1 month after treatment started, pain and shortness of breath increased at 3 months, and disturbed sleep, drowsiness, and numbness increased after 6 months. Fatigue and dry mouth increased at 3 months after treatment started and then decreased. Only distress decreased throughout the course of treatment. Conclusion: The findings may lead to the development of better clinical guidelines and improved information for patients on when to expect the greatest impact from their symptoms during the course of treatment. © 2014 MA Healthcare Ltd.-
dc.languageeng-
dc.relation.ispartofInternational Journal of Palliative Nursing-
dc.subjectNon-small cell lung cancer-
dc.subjectTargeted therap-
dc.subjectSymptom severity-
dc.subjectSymptom interference-
dc.subjectGefitinib treatment-
dc.titleChanges in symptom severity in Taiwanese lung cancer patients after gefitinib treatment: A pilot study-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.12968/ijpn.2014.20.3.135-
dc.identifier.pmid24675540-
dc.identifier.scopuseid_2-s2.0-84901920694-
dc.identifier.volume20-
dc.identifier.issue3-
dc.identifier.spage135-
dc.identifier.epage142-
dc.identifier.isiWOS:000214482700008-
dc.identifier.issnl1357-6321-

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