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- Publisher Website: 10.1007/s00520-009-0583-9
- Scopus: eid_2-s2.0-70349323426
- PMID: 19214595
- WOS: WOS:000269973800007
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Article: A longitudinal study of the role of patient-reported outcomes on survival prediction of palliative cancer inpatients in Taiwan
Title | A longitudinal study of the role of patient-reported outcomes on survival prediction of palliative cancer inpatients in Taiwan |
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Authors | |
Keywords | Prognostic factor Quality of life Survival Symptom severity Palliative patients |
Issue Date | 2009 |
Citation | Supportive Care in Cancer, 2009, v. 17, n. 10, p. 1285-1294 How to Cite? |
Abstract | This study explores the significance of patient-reported outcomes for predicting length of survival of palliative cancer patients. Patients were recruited upon admission to the inpatient palliative care unit. Weekly assessment of 180 terminal cancer patients was carried out throughout their survival time using the Medical Outcome Study 36-Item Short-Form Health Survey, the Taiwanese version of the M.D. Anderson Symptom Inventory (MDASI-T), the Karnofsky Performance Status (KPS), the Brief Pain Inventory, and the Brief Fatigue Inventory. Generalized estimating equations (GEE) were utilized to analyze whether the patient-reported outcomes predicted survival time. Of all patients, 64 had one assessment, 51 had two, 25 had three, and 40 had four or more assessments, up to a maximum of eight. The univariate analysis showed that gender (P∈<∈0.01), KPS (P∈<∈0.01), the physical component summary score (P∈=∈0.02), the MDASI-T total score (P∈<∈0.01), composite fatigue severity (P∈<∈0.01), and composite pain severity (P∈<∈0.01) were significantly associated with length of survival. The multivariate analysis showed that gender (P∈<∈0.01), KPS (P∈<∈0.01), and the MDASI-T total score (P∈=∈0.01) were significant predictors of survival time. This is the first study to explore the significance of patient-related outcomes for predicting length of survival of palliative cancer patients using the GEE method. This study confirms that overall symptom severity is a significant factor in assessing the length of survival of palliative cancer patients. © 2009 Springer-Verlag. |
Persistent Identifier | http://hdl.handle.net/10722/241176 |
ISSN | 2023 Impact Factor: 2.8 2023 SCImago Journal Rankings: 1.007 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chang, Jing An | - |
dc.contributor.author | Lin, Chia Chin | - |
dc.date.accessioned | 2017-05-26T03:37:01Z | - |
dc.date.available | 2017-05-26T03:37:01Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Supportive Care in Cancer, 2009, v. 17, n. 10, p. 1285-1294 | - |
dc.identifier.issn | 0941-4355 | - |
dc.identifier.uri | http://hdl.handle.net/10722/241176 | - |
dc.description.abstract | This study explores the significance of patient-reported outcomes for predicting length of survival of palliative cancer patients. Patients were recruited upon admission to the inpatient palliative care unit. Weekly assessment of 180 terminal cancer patients was carried out throughout their survival time using the Medical Outcome Study 36-Item Short-Form Health Survey, the Taiwanese version of the M.D. Anderson Symptom Inventory (MDASI-T), the Karnofsky Performance Status (KPS), the Brief Pain Inventory, and the Brief Fatigue Inventory. Generalized estimating equations (GEE) were utilized to analyze whether the patient-reported outcomes predicted survival time. Of all patients, 64 had one assessment, 51 had two, 25 had three, and 40 had four or more assessments, up to a maximum of eight. The univariate analysis showed that gender (P∈<∈0.01), KPS (P∈<∈0.01), the physical component summary score (P∈=∈0.02), the MDASI-T total score (P∈<∈0.01), composite fatigue severity (P∈<∈0.01), and composite pain severity (P∈<∈0.01) were significantly associated with length of survival. The multivariate analysis showed that gender (P∈<∈0.01), KPS (P∈<∈0.01), and the MDASI-T total score (P∈=∈0.01) were significant predictors of survival time. This is the first study to explore the significance of patient-related outcomes for predicting length of survival of palliative cancer patients using the GEE method. This study confirms that overall symptom severity is a significant factor in assessing the length of survival of palliative cancer patients. © 2009 Springer-Verlag. | - |
dc.language | eng | - |
dc.relation.ispartof | Supportive Care in Cancer | - |
dc.subject | Prognostic factor | - |
dc.subject | Quality of life | - |
dc.subject | Survival | - |
dc.subject | Symptom severity | - |
dc.subject | Palliative patients | - |
dc.title | A longitudinal study of the role of patient-reported outcomes on survival prediction of palliative cancer inpatients in Taiwan | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1007/s00520-009-0583-9 | - |
dc.identifier.pmid | 19214595 | - |
dc.identifier.scopus | eid_2-s2.0-70349323426 | - |
dc.identifier.volume | 17 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 1285 | - |
dc.identifier.epage | 1294 | - |
dc.identifier.isi | WOS:000269973800007 | - |
dc.identifier.issnl | 0941-4355 | - |