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Conference Paper: Characterization of Extensive Microstructural Variations associated with Punctate White Matter Lesions in Preterm Neonates
Title | Characterization of Extensive Microstructural Variations associated with Punctate White Matter Lesions in Preterm Neonates |
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Authors | |
Issue Date | 2017 |
Publisher | International Society for Magnetic Resonance in Medicine. |
Citation | The 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 22-27 April 2017. In Conference Proceedings, 2017, abstract no. 4101 How to Cite? |
Abstract | Punctate white matter lesions (PWML) are common in preterm neonates. Neurodevelopmental outcome of the neonates is related to the lesion extensions. This study aimed to characterize the extent of microstructural variations for different PWML grades. White matter microstructural variations were different across PWML grades. The severe PWML were associated with extensive microstructural changes. Pattern of increased AD, increased RD, and reduced/unchanged FA was found proximal to the PWML. Unchanged AD, increased RD, and reduced/unchanged FA were observed in the vast regions distal from the PWML. These findings may help in determining outcomes of PWML and treatment strategies. |
Persistent Identifier | http://hdl.handle.net/10722/240987 |
DC Field | Value | Language |
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dc.contributor.author | Li, X | - |
dc.contributor.author | Gao, J | - |
dc.contributor.author | Wang, M | - |
dc.contributor.author | Hui, SK | - |
dc.contributor.author | Wei, X | - |
dc.contributor.author | Yang, J | - |
dc.date.accessioned | 2017-05-22T09:20:38Z | - |
dc.date.available | 2017-05-22T09:20:38Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | The 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), Honolulu, HI., 22-27 April 2017. In Conference Proceedings, 2017, abstract no. 4101 | - |
dc.identifier.uri | http://hdl.handle.net/10722/240987 | - |
dc.description.abstract | Punctate white matter lesions (PWML) are common in preterm neonates. Neurodevelopmental outcome of the neonates is related to the lesion extensions. This study aimed to characterize the extent of microstructural variations for different PWML grades. White matter microstructural variations were different across PWML grades. The severe PWML were associated with extensive microstructural changes. Pattern of increased AD, increased RD, and reduced/unchanged FA was found proximal to the PWML. Unchanged AD, increased RD, and reduced/unchanged FA were observed in the vast regions distal from the PWML. These findings may help in determining outcomes of PWML and treatment strategies. | - |
dc.language | eng | - |
dc.publisher | International Society for Magnetic Resonance in Medicine. | - |
dc.relation.ispartof | ISMRM 2017 Annual Meeting & Exhibition Proceedings | - |
dc.title | Characterization of Extensive Microstructural Variations associated with Punctate White Matter Lesions in Preterm Neonates | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Hui, SK: edshui@hku.hk | - |
dc.identifier.authority | Hui, SK=rp01832 | - |
dc.identifier.hkuros | 272203 | - |
dc.publisher.place | United States | - |