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Conference Paper: Neurochemical basis of the BOLD change in attention control - a combined task-based fMRI and 1H-MRS

TitleNeurochemical basis of the BOLD change in attention control - a combined task-based fMRI and 1H-MRS
Authors
Chiu, PWZhang, HIp, IWong, SWHLiu, TWong, GHYChan, QYau, KKWChu, LWMak, HKF
Issue Date2017
PublisherInternational Society for Magnetic Resonance in Medicine.
Citation
The 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and 26th Annual Meeting of The Section for Magnetic Resonance Technologists (SMRT), Honolulu, HI., 22-27 April 2017, abstract no. 5396 How to Cite?
AbstractfMRI can indirectly measure brain activity, but the biochemical underpinnings of the BOLD changes are still unknown. Nevertheless, 1H-MRS can bridge such gap by measuring Glx [summation of glutamate (Glu) and glutamine (Gln)], where Glu is one of the mediators of neurovascular coupling. In this study, we aim to elucidate the complex relationship between attention control (numerical Stroop) and its associated neurochemical changes by combining the biochemical information from task-based fMRI and 1H-MRS. Our result showed that the anterior cingulate cortex was positively correlated with Glx. This is the first study providing neurochemical explanation of the BOLD change during attention control task.
Persistent Identifierhttp://hdl.handle.net/10722/239182

 

DC FieldValueLanguage
dc.contributor.authorChiu, PW-
dc.contributor.authorZhang, H-
dc.contributor.authorIp, I-
dc.contributor.authorWong, SWH-
dc.contributor.authorLiu, T-
dc.contributor.authorWong, GHY-
dc.contributor.authorChan, Q-
dc.contributor.authorYau, KKW-
dc.contributor.authorChu, LW-
dc.contributor.authorMak, HKF-
dc.date.accessioned2017-03-10T01:33:03Z-
dc.date.available2017-03-10T01:33:03Z-
dc.date.issued2017-
dc.identifier.citationThe 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and 26th Annual Meeting of The Section for Magnetic Resonance Technologists (SMRT), Honolulu, HI., 22-27 April 2017, abstract no. 5396-
dc.identifier.urihttp://hdl.handle.net/10722/239182-
dc.description.abstractfMRI can indirectly measure brain activity, but the biochemical underpinnings of the BOLD changes are still unknown. Nevertheless, 1H-MRS can bridge such gap by measuring Glx [summation of glutamate (Glu) and glutamine (Gln)], where Glu is one of the mediators of neurovascular coupling. In this study, we aim to elucidate the complex relationship between attention control (numerical Stroop) and its associated neurochemical changes by combining the biochemical information from task-based fMRI and 1H-MRS. Our result showed that the anterior cingulate cortex was positively correlated with Glx. This is the first study providing neurochemical explanation of the BOLD change during attention control task.-
dc.languageeng-
dc.publisherInternational Society for Magnetic Resonance in Medicine.-
dc.relation.ispartofISMRM-SMRT 2017-
dc.titleNeurochemical basis of the BOLD change in attention control - a combined task-based fMRI and 1H-MRS-
dc.typeConference_Paper-
dc.identifier.emailChiu, PW: pwcchiu@hku.hk-
dc.identifier.emailLiu, T: tianyin@hku.hk-
dc.identifier.emailWong, GHY: ghywong@hku.hk-
dc.identifier.emailChu, LW: lwchu@hkucc.hku.hk-
dc.identifier.emailMak, HKF: makkf@hkucc.hku.hk-
dc.identifier.authorityWong, GHY=rp01850-
dc.identifier.authorityMak, HKF=rp00533-
dc.identifier.hkuros271544-
dc.publisher.placeUnited States-

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