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Article: Randomized Clinical Trial on Preventing Root Caries among Community-Dwelling Elders
Title | Randomized Clinical Trial on Preventing Root Caries among Community-Dwelling Elders |
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Authors | |
Keywords | Dental caries Elderly Fluorides Potassium iodide Preventive dentistry Silver |
Issue Date | 2017 |
Publisher | SAGE Publications. The Journal's web site is located at http://jct.sagepub.com/ |
Citation | JDR Clinical & Translational Research, 2017, v. 2 n. 1, p. 66-72 How to Cite? |
Abstract | Dental root caries is a common disease among elders. More efforts on preventing this disease are needed. Silver diammine fluoride (SDF) is known to prevent dental caries in primary teeth. However, clinical evidence of its efficacy in preventing root surface caries is limited. This clinical trial aimed to compare the effectiveness of SDF in preventing root caries among elders in a water fluoridated area. A total of 323 elders who had at least 5 teeth with exposed root surfaces and who had self-care ability were randomly allocated into 3 intervention groups: group 1 (placebo control), annual application of tonic water; group 2, annual application of SDF solution; group 3, annual application of SDF solution, immediately followed by potassium iodide (KI) solution. Oral hygiene instructions and fluoride toothpaste were provided to all subjects. Status of dental root surface was assessed every 6 mo by the same independent examiner. After 30 mo, 257 (79.6%) elders were reviewed. The mean numbers of root surface with new caries experience in the control, SDF, and SDF/KI groups were 1.1, 0.4, and 0.5, respectively (analysis of variance, P < 0.001). Scheffe’s multiple comparison showed that elders who received placebo developed more new root caries lesions (P < 0.05), while the difference between the SDF and SDF/KI groups was not statistically significant (P > 0.05). Moreover, elders who had higher visible plaque index scores at 30-mo examination (analysis of covariance, P < 0.001) and those who had higher baseline DMFT scores (analysis of covariance, P = 0.005) developed more new root caries. It is concluded that annual application of SDF or SDF/KI solution is effective in preventing root caries among community-dwelling elders in a fluoridated area (ClinicalTrials.gov NCT02360124). |
Persistent Identifier | http://hdl.handle.net/10722/238634 |
ISSN | 2023 Impact Factor: 2.2 2023 SCImago Journal Rankings: 0.905 |
DC Field | Value | Language |
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dc.contributor.author | Li, R | - |
dc.contributor.author | Lo, ECM | - |
dc.contributor.author | Liu, BY | - |
dc.contributor.author | Wong, MCM | - |
dc.contributor.author | Chu, CH | - |
dc.date.accessioned | 2017-02-20T01:24:03Z | - |
dc.date.available | 2017-02-20T01:24:03Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | JDR Clinical & Translational Research, 2017, v. 2 n. 1, p. 66-72 | - |
dc.identifier.issn | 2380-0844 | - |
dc.identifier.uri | http://hdl.handle.net/10722/238634 | - |
dc.description.abstract | Dental root caries is a common disease among elders. More efforts on preventing this disease are needed. Silver diammine fluoride (SDF) is known to prevent dental caries in primary teeth. However, clinical evidence of its efficacy in preventing root surface caries is limited. This clinical trial aimed to compare the effectiveness of SDF in preventing root caries among elders in a water fluoridated area. A total of 323 elders who had at least 5 teeth with exposed root surfaces and who had self-care ability were randomly allocated into 3 intervention groups: group 1 (placebo control), annual application of tonic water; group 2, annual application of SDF solution; group 3, annual application of SDF solution, immediately followed by potassium iodide (KI) solution. Oral hygiene instructions and fluoride toothpaste were provided to all subjects. Status of dental root surface was assessed every 6 mo by the same independent examiner. After 30 mo, 257 (79.6%) elders were reviewed. The mean numbers of root surface with new caries experience in the control, SDF, and SDF/KI groups were 1.1, 0.4, and 0.5, respectively (analysis of variance, P < 0.001). Scheffe’s multiple comparison showed that elders who received placebo developed more new root caries lesions (P < 0.05), while the difference between the SDF and SDF/KI groups was not statistically significant (P > 0.05). Moreover, elders who had higher visible plaque index scores at 30-mo examination (analysis of covariance, P < 0.001) and those who had higher baseline DMFT scores (analysis of covariance, P = 0.005) developed more new root caries. It is concluded that annual application of SDF or SDF/KI solution is effective in preventing root caries among community-dwelling elders in a fluoridated area (ClinicalTrials.gov NCT02360124). | - |
dc.language | eng | - |
dc.publisher | SAGE Publications. The Journal's web site is located at http://jct.sagepub.com/ | - |
dc.relation.ispartof | JDR Clinical & Translational Research | - |
dc.rights | JDR Clinical & Translational Research. Copyright © SAGE Publications. | - |
dc.subject | Dental caries | - |
dc.subject | Elderly | - |
dc.subject | Fluorides | - |
dc.subject | Potassium iodide | - |
dc.subject | Preventive dentistry | - |
dc.subject | Silver | - |
dc.title | Randomized Clinical Trial on Preventing Root Caries among Community-Dwelling Elders | - |
dc.type | Article | - |
dc.identifier.email | Lo, ECM: edward-lo@hku.hk | - |
dc.identifier.email | Wong, MCM: mcmwong@hku.hk | - |
dc.identifier.email | Chu, CH: chchu@hku.hk | - |
dc.identifier.authority | Lo, ECM=rp00015 | - |
dc.identifier.authority | Wong, MCM=rp00024 | - |
dc.identifier.authority | Chu, CH=rp00022 | - |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1177/2380084416668491 | - |
dc.identifier.pmid | 30938645 | - |
dc.identifier.scopus | eid_2-s2.0-85050355635 | - |
dc.identifier.hkuros | 271303 | - |
dc.identifier.volume | 2 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 66 | - |
dc.identifier.epage | 72 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 2380-0844 | - |