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Book Chapter: Cell cycle and cell cycle regulators in the process of development, pluripotency, differentiation, and reprogramming
Title | Cell cycle and cell cycle regulators in the process of development, pluripotency, differentiation, and reprogramming |
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Authors | |
Keywords | Asymmetric cell division Cell cycle Cell cycle regulators Cell fate decision Cyclin dependent kinases (CDKs) |
Issue Date | 2016 |
Publisher | Bentham Science Publishers Ltd. |
Citation | Cell cycle and cell cycle regulators in the process of development, pluripotency, differentiation, and reprogramming. In Atta-ur-Rahman & Shazia Anjum (Eds.), Frontiers in Stem Cell and Regenerative Medicine Research, v. 2, p. 176-189. Sharjah, UAE: Bentham Science Publishers Ltd, 2016 How to Cite? |
Abstract | The core cell cycle machinery and its associated signaling pathways play critical roles in regulation of stem cell properties. Cell cycle length and rate is a determining factor for stem cells to maintain pluripotency or undergo differentiation. Manipulating the cell cycle has functional consequences for tissue differentiation as well as somatic cell reprogramming. In addition, accumulating evidence indicates that cell cycle regulators may control pluripotency and differentiation by direct interaction with the pluripotency network and other essential signal pathways without altering the cell cycle per se. In this chapter, we summarize the current understanding of the role of the cell cycle and cell cycle regulators in the process of development, pluripotency, differentiation, and reprogramming. |
Persistent Identifier | http://hdl.handle.net/10722/233419 |
ISBN |
DC Field | Value | Language |
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dc.contributor.author | Wang, X | - |
dc.contributor.author | Stanbridge, EJ | - |
dc.date.accessioned | 2016-09-20T05:36:41Z | - |
dc.date.available | 2016-09-20T05:36:41Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Cell cycle and cell cycle regulators in the process of development, pluripotency, differentiation, and reprogramming. In Atta-ur-Rahman & Shazia Anjum (Eds.), Frontiers in Stem Cell and Regenerative Medicine Research, v. 2, p. 176-189. Sharjah, UAE: Bentham Science Publishers Ltd, 2016 | - |
dc.identifier.isbn | 978-1-68108-184-7 | - |
dc.identifier.uri | http://hdl.handle.net/10722/233419 | - |
dc.description.abstract | The core cell cycle machinery and its associated signaling pathways play critical roles in regulation of stem cell properties. Cell cycle length and rate is a determining factor for stem cells to maintain pluripotency or undergo differentiation. Manipulating the cell cycle has functional consequences for tissue differentiation as well as somatic cell reprogramming. In addition, accumulating evidence indicates that cell cycle regulators may control pluripotency and differentiation by direct interaction with the pluripotency network and other essential signal pathways without altering the cell cycle per se. In this chapter, we summarize the current understanding of the role of the cell cycle and cell cycle regulators in the process of development, pluripotency, differentiation, and reprogramming. | - |
dc.language | eng | - |
dc.publisher | Bentham Science Publishers Ltd. | - |
dc.relation.ispartof | Frontiers in Stem Cell and Regenerative Medicine Research | - |
dc.subject | Asymmetric cell division | - |
dc.subject | Cell cycle | - |
dc.subject | Cell cycle regulators | - |
dc.subject | Cell fate decision | - |
dc.subject | Cyclin dependent kinases (CDKs) | - |
dc.title | Cell cycle and cell cycle regulators in the process of development, pluripotency, differentiation, and reprogramming | - |
dc.type | Book_Chapter | - |
dc.identifier.email | Wang, X: xqwang@hku.hk | - |
dc.identifier.authority | Wang, X=rp00507 | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.2174/97816810818301150201 | - |
dc.identifier.hkuros | 263646 | - |
dc.identifier.volume | 2 | - |
dc.identifier.spage | 176 | - |
dc.identifier.epage | 189 | - |
dc.publisher.place | Sharjah, UAE | - |