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- Publisher Website: 10.1109/JSTQE.2015.2512978
- Scopus: eid_2-s2.0-84964344465
- WOS: WOS:000373066500001
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Article: Optical Time Stretch for High-Speed and High-Throughput Imaging—From Single-Cell to Tissue-Wide Scales
Title | Optical Time Stretch for High-Speed and High-Throughput Imaging—From Single-Cell to Tissue-Wide Scales |
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Authors | |
Keywords | Medical and biological imaging optical coherence tomography optical time-stretch quantitative phase imaging ultrafast technology |
Issue Date | 2015 |
Publisher | IEEE. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=2944 |
Citation | IEEE Journal of Selected Topics in Quantum Electronics, 2015, v. 22 n. 4, p. article no. 6803115 How to Cite? |
Abstract | Initially developed for high-speed optical communica- tion, optical time stretch has recently been adopted for ultrafast and sensitive optical imaging at an unprecedented speed. In this paper, we highlight the essential concepts as well as the enabling elements of this ultrafast technology. More importantly, we review the re- cent developments of optical time-stretch imaging, especially in the context of 1) quantitative optofluidic microscopy for high-content single-cell phenotyping at an imaging throughput ∼100 000 cells/s; 2) all-optical multi-MHz (>10 MHz) swept-source optical coher- ence tomography (OCT) for high-speed in vivo anatomical and functional 3-D tissue imaging. We also discuss the current techno- logical challenges in time-stretch imaging. In particular, generating the enormous data in real time, this technology could uniquely cre- ate new insights of data-driven science in clinical diagnostics and basic biological research. |
Persistent Identifier | http://hdl.handle.net/10722/229200 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 1.283 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lau, KSA | - |
dc.contributor.author | Tang, HL | - |
dc.contributor.author | Xu, J | - |
dc.contributor.author | Wei, X | - |
dc.contributor.author | Wong, KKY | - |
dc.contributor.author | Tsia, KKM | - |
dc.date.accessioned | 2016-08-23T14:09:36Z | - |
dc.date.available | 2016-08-23T14:09:36Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | IEEE Journal of Selected Topics in Quantum Electronics, 2015, v. 22 n. 4, p. article no. 6803115 | - |
dc.identifier.issn | 1077-260X | - |
dc.identifier.uri | http://hdl.handle.net/10722/229200 | - |
dc.description.abstract | Initially developed for high-speed optical communica- tion, optical time stretch has recently been adopted for ultrafast and sensitive optical imaging at an unprecedented speed. In this paper, we highlight the essential concepts as well as the enabling elements of this ultrafast technology. More importantly, we review the re- cent developments of optical time-stretch imaging, especially in the context of 1) quantitative optofluidic microscopy for high-content single-cell phenotyping at an imaging throughput ∼100 000 cells/s; 2) all-optical multi-MHz (>10 MHz) swept-source optical coher- ence tomography (OCT) for high-speed in vivo anatomical and functional 3-D tissue imaging. We also discuss the current techno- logical challenges in time-stretch imaging. In particular, generating the enormous data in real time, this technology could uniquely cre- ate new insights of data-driven science in clinical diagnostics and basic biological research. | - |
dc.language | eng | - |
dc.publisher | IEEE. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=2944 | - |
dc.relation.ispartof | IEEE Journal of Selected Topics in Quantum Electronics | - |
dc.rights | IEEE Journal of Selected Topics in Quantum Electronics. Copyright © IEEE. | - |
dc.rights | ©20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. | - |
dc.subject | Medical and biological imaging | - |
dc.subject | optical coherence tomography | - |
dc.subject | optical time-stretch | - |
dc.subject | quantitative phase imaging | - |
dc.subject | ultrafast technology | - |
dc.title | Optical Time Stretch for High-Speed and High-Throughput Imaging—From Single-Cell to Tissue-Wide Scales | - |
dc.type | Article | - |
dc.identifier.email | Lau, KSA: kslau718@hku.hk | - |
dc.identifier.email | Wei, X: xmwei@hku.hk | - |
dc.identifier.email | Wong, KKY: kywong@eee.hku.hk | - |
dc.identifier.email | Tsia, KKM: tsia@hku.hk | - |
dc.identifier.authority | Wong, KKY=rp00189 | - |
dc.identifier.authority | Tsia, KKM=rp01389 | - |
dc.identifier.doi | 10.1109/JSTQE.2015.2512978 | - |
dc.identifier.scopus | eid_2-s2.0-84964344465 | - |
dc.identifier.hkuros | 262133 | - |
dc.identifier.volume | 22 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | article no. 6803115 | - |
dc.identifier.epage | article no. 6803115 | - |
dc.identifier.isi | WOS:000373066500001 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1077-260X | - |