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Article: Ultrastructural calcification of glomerular immune complexes
Title | Ultrastructural calcification of glomerular immune complexes |
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Authors | |
Keywords | Granulomatous inflammation |
Issue Date | 1996 |
Citation | Modern Pathology, 1996, v. 9, n. 1, p. 36-40 How to Cite? |
Abstract | We report a previously undescribed ultrastructural calcification of glomerular immune complex depositions in a patient with lupus nephritis. Such processes give rise to a distinctive ultrastructural calcified microspheriol in electron-dense immune deposits, and were associated with hypercalcemia and nephrocalcinosis. The cause of hypercalcemia in this patient was uncertain, but related to a granulomatous inflammation and abscess of the breast. Whereas ultrastructural microcalcification was associated with hypercalcemia, its distribution in the segmental glomerular lesions suggests that an inflammatory process was contributory. The clinical follow-up indicates that the microcalcifications of immune complexes have not affected the outcome of nephritis and renal function. |
Persistent Identifier | http://hdl.handle.net/10722/228484 |
ISSN | 2023 Impact Factor: 7.1 2023 SCImago Journal Rankings: 2.328 |
DC Field | Value | Language |
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dc.contributor.author | Lai, F. Mac Moune | - |
dc.contributor.author | To, K. F. | - |
dc.contributor.author | Wang, Angela | - |
dc.contributor.author | Choi, P. C L | - |
dc.contributor.author | Cheng, J. S K | - |
dc.contributor.author | Chew, E. C. | - |
dc.date.accessioned | 2016-08-13T08:02:32Z | - |
dc.date.available | 2016-08-13T08:02:32Z | - |
dc.date.issued | 1996 | - |
dc.identifier.citation | Modern Pathology, 1996, v. 9, n. 1, p. 36-40 | - |
dc.identifier.issn | 0893-3952 | - |
dc.identifier.uri | http://hdl.handle.net/10722/228484 | - |
dc.description.abstract | We report a previously undescribed ultrastructural calcification of glomerular immune complex depositions in a patient with lupus nephritis. Such processes give rise to a distinctive ultrastructural calcified microspheriol in electron-dense immune deposits, and were associated with hypercalcemia and nephrocalcinosis. The cause of hypercalcemia in this patient was uncertain, but related to a granulomatous inflammation and abscess of the breast. Whereas ultrastructural microcalcification was associated with hypercalcemia, its distribution in the segmental glomerular lesions suggests that an inflammatory process was contributory. The clinical follow-up indicates that the microcalcifications of immune complexes have not affected the outcome of nephritis and renal function. | - |
dc.language | eng | - |
dc.relation.ispartof | Modern Pathology | - |
dc.subject | Granulomatous inflammation | - |
dc.title | Ultrastructural calcification of glomerular immune complexes | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.pmid | 8821954 | - |
dc.identifier.scopus | eid_2-s2.0-9044233258 | - |
dc.identifier.volume | 9 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 36 | - |
dc.identifier.epage | 40 | - |
dc.identifier.issnl | 0893-3952 | - |