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Article: IgA nephropathy: Common nephritis leading to end-stage renal failure
Title | IgA nephropathy: Common nephritis leading to end-stage renal failure |
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Authors | |
Keywords | IgA nephropathy |
Issue Date | 1994 |
Citation | International Journal of Artificial Organs, 1994, v. 17, n. 9, p. 457-460 How to Cite? |
Abstract | IgA nephropathy (IgAN) characterized by mesangial proliferative glomerulonephritis with predominant mesangial IgA deposition is the commonest glomerulonephritis worldwide. In contrast to the initial report indicated a favorable prognosis, subsequent reports have shown a highly variable outcome leading to end-stage renal failure (ESRF) in a significant proportion of patients. Many centers report a high incidence (ranging from 10-22%) of patients with idiopathic IgAN amongst the total population, of patients on maintenance dialysis. Most of these patients develop ESRF at their middle-age and hence, will pose a significant and important workload in the dialysis and transplantation programme. Because IgAN is a disease with a variable rate of progression leading to chronic renal failure amongst younger patients and with neither effective nor specific treatment, identification of the clinical and pathologic prognostic indicators for these patients is of paramount importance in planning the long-term renal replacement program. |
Persistent Identifier | http://hdl.handle.net/10722/228422 |
ISSN | 2023 Impact Factor: 1.4 2023 SCImago Journal Rankings: 0.430 |
DC Field | Value | Language |
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dc.contributor.author | Lai, K. N. | - |
dc.contributor.author | Wang, A. Y M | - |
dc.date.accessioned | 2016-08-13T08:02:22Z | - |
dc.date.available | 2016-08-13T08:02:22Z | - |
dc.date.issued | 1994 | - |
dc.identifier.citation | International Journal of Artificial Organs, 1994, v. 17, n. 9, p. 457-460 | - |
dc.identifier.issn | 0391-3988 | - |
dc.identifier.uri | http://hdl.handle.net/10722/228422 | - |
dc.description.abstract | IgA nephropathy (IgAN) characterized by mesangial proliferative glomerulonephritis with predominant mesangial IgA deposition is the commonest glomerulonephritis worldwide. In contrast to the initial report indicated a favorable prognosis, subsequent reports have shown a highly variable outcome leading to end-stage renal failure (ESRF) in a significant proportion of patients. Many centers report a high incidence (ranging from 10-22%) of patients with idiopathic IgAN amongst the total population, of patients on maintenance dialysis. Most of these patients develop ESRF at their middle-age and hence, will pose a significant and important workload in the dialysis and transplantation programme. Because IgAN is a disease with a variable rate of progression leading to chronic renal failure amongst younger patients and with neither effective nor specific treatment, identification of the clinical and pathologic prognostic indicators for these patients is of paramount importance in planning the long-term renal replacement program. | - |
dc.language | eng | - |
dc.relation.ispartof | International Journal of Artificial Organs | - |
dc.subject | IgA nephropathy | - |
dc.title | IgA nephropathy: Common nephritis leading to end-stage renal failure | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.pmid | 7890432 | - |
dc.identifier.scopus | eid_2-s2.0-0028138322 | - |
dc.identifier.volume | 17 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 457 | - |
dc.identifier.epage | 460 | - |
dc.identifier.issnl | 0391-3988 | - |