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Patent History
- ApplicationUS 12/4824316 2015-08-12
- PublicationUS 20160045521 2016-02-18
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published patent: BIOPHOSPHONATE COMPOUNDS AND GAMMA DELTA T CELL-MEDIATED THERAPY FOR TREATING EPSTEIN-BARR VIRUS-ASSOCIATED DISORDERS
| Title | BIOPHOSPHONATE COMPOUNDS AND GAMMA DELTA T CELL-MEDIATED THERAPY FOR TREATING EPSTEIN-BARR VIRUS-ASSOCIATED DISORDERS |
|---|---|
| Priority Date | 2015-08-12 US 12/4824316 2014-08-12 US 12/2036487P |
| Inventors | |
| Issue Date | 2016 |
| Citation | US Published patent application US 20160045521. Washington, DC: US Patent and Trademark Office (USPTO), 2016 How to Cite? |
| Abstract | Aminobisphosphonate pamidronate (PAM) can control Epstein-Barr virus (EBV) associated disorders in humanized mice through a V[gamma]9V[delta]2-T-cell dependent mechanism. This suggests a strong potential for a therapeutic approach using PAM to boost human V[gamma]9V[delta]2-T-cell immunity against EBV associated disorders, such as the lymphoproliferative disease (LPD), posttransplant lymphoproliferative disorder (PLPD), Hodgkin's disease, Burkitt's lymphoma, and nasopharyngeal carcinoma (NPC). |
| Persistent Identifier | http://hdl.handle.net/10722/225268 |
| DC Field | Value | Language |
|---|---|---|
| dc.date.accessioned | 2016-05-03T05:10:11Z | - |
| dc.date.available | 2016-05-03T05:10:11Z | - |
| dc.date.issued | 2016 | - |
| dc.identifier.citation | US Published patent application US 20160045521. Washington, DC: US Patent and Trademark Office (USPTO), 2016 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/225268 | - |
| dc.description.abstract | Aminobisphosphonate pamidronate (PAM) can control Epstein-Barr virus (EBV) associated disorders in humanized mice through a V[gamma]9V[delta]2-T-cell dependent mechanism. This suggests a strong potential for a therapeutic approach using PAM to boost human V[gamma]9V[delta]2-T-cell immunity against EBV associated disorders, such as the lymphoproliferative disease (LPD), posttransplant lymphoproliferative disorder (PLPD), Hodgkin's disease, Burkitt's lymphoma, and nasopharyngeal carcinoma (NPC). | - |
| dc.title | BIOPHOSPHONATE COMPOUNDS AND GAMMA DELTA T CELL-MEDIATED THERAPY FOR TREATING EPSTEIN-BARR VIRUS-ASSOCIATED DISORDERS | - |
| dc.type | Patent | - |
| dc.identifier.authority | TU WENWEI=rp00416 | - |
| dc.identifier.authority | LIU YINPING=rp00269 | - |
| dc.description.nature | published_or_final_version | - |
| dc.contributor.inventor | TU WENWEI | - |
| dc.contributor.inventor | XIANG ZHENG | - |
| dc.contributor.inventor | LIU YINPING | - |
| patents.identifier.application | US 12/4824316 | - |
| patents.description.assignee | UNIV HONG KONG [HK] | - |
| patents.description.country | United States of America | - |
| patents.date.publication | 2016-02-18 | - |
| patents.identifier.hkutechid | PAED-2014-00536-1 | - |
| patents.date.application | 2015-08-12 | - |
| patents.date.priority | 2015-08-12 US 12/4824316 | - |
| patents.date.priority | 2014-08-12 US 12/2036487P | - |
| patents.description.cc | us | - |
| patents.identifier.publication | US 20160045521 | - |
| patents.relation.family | WO 2016023491 (A1) 2016-02-18 | - |
| patents.description.kind | A1 | - |
| patents.type | Patent_published | - |