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- Publisher Website: 10.1093/bioinformatics/btq492
- Scopus: eid_2-s2.0-77957768673
- PMID: 20801910
- WOS: WOS:000282749700008
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Article: A study of the efficiency of pooling in haplotype estimation
Title | A study of the efficiency of pooling in haplotype estimation |
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Authors | |
Keywords | Algorithms Haplotypes |
Issue Date | 2010 |
Citation | Bioinformatics (Oxford, England), 2010, v. 26, n. 20, p. 2556-2563 How to Cite? |
Abstract | It has been claimed in the literature that pooling DNA samples is efficient in estimating haplotype frequencies. There is, however, no theoretical justification based on calculation of statistical efficiency. In fact, the limited evidence given so far is based on simulation studies with small numbers of loci. With rapid advance in technology, it is of interest to see if pooling is still efficient when the number of loci increases. |
Persistent Identifier | http://hdl.handle.net/10722/221687 |
ISSN | 2023 Impact Factor: 4.4 2023 SCImago Journal Rankings: 2.574 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Kuk, AYC | - |
dc.contributor.author | Xu, J | - |
dc.contributor.author | Yang, Y | - |
dc.date.accessioned | 2015-12-04T15:29:07Z | - |
dc.date.available | 2015-12-04T15:29:07Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Bioinformatics (Oxford, England), 2010, v. 26, n. 20, p. 2556-2563 | - |
dc.identifier.issn | 1367-4803 | - |
dc.identifier.uri | http://hdl.handle.net/10722/221687 | - |
dc.description.abstract | It has been claimed in the literature that pooling DNA samples is efficient in estimating haplotype frequencies. There is, however, no theoretical justification based on calculation of statistical efficiency. In fact, the limited evidence given so far is based on simulation studies with small numbers of loci. With rapid advance in technology, it is of interest to see if pooling is still efficient when the number of loci increases. | - |
dc.language | eng | - |
dc.relation.ispartof | Bioinformatics (Oxford, England) | - |
dc.subject | Algorithms | - |
dc.subject | Haplotypes | - |
dc.title | A study of the efficiency of pooling in haplotype estimation | - |
dc.type | Article | - |
dc.identifier.email | Xu, J: xujf@hku.hk | - |
dc.identifier.authority | Xu, J=rp02086 | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1093/bioinformatics/btq492 | - |
dc.identifier.pmid | 20801910 | - |
dc.identifier.scopus | eid_2-s2.0-77957768673 | - |
dc.identifier.volume | 26 | - |
dc.identifier.spage | 2556 | - |
dc.identifier.epage | 2563 | - |
dc.identifier.isi | WOS:000282749700008 | - |
dc.identifier.issnl | 1367-4803 | - |