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Patent History
- ApplicationUS 12/4597408 2015-01-15
- PublicationUS 20150219676 2015-08-06
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Patent: BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL
| Title | BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL |
|---|---|
| Priority Date | 2015-01-15 US 12/4597408 2014-01-31 US 12/1934335P |
| Inventors | |
| Issue Date | 2015 |
| Citation | US Published patent application US 20150219676. Washington, DC: US Patent and Trademark Office (USPTO), 2015 How to Cite? |
| Abstract | The invention provides fluorogenic compounds and probes that can be used as reagents for measuring, detecting and/or screening superoxide. The fluorogenic compounds of the invention can produce fluorescence colors, such as green, yellow, red, or far-red. The invention further provides fluorogenic compounds for selectively staining superoxide in the mitochondria of living cells. The invention also provides methods that can be used to measure, directly or indirectly, the presence and/or amount of superoxide in chemical samples and biological samples such as cells and tissues in living organisms, and a high-throughput screening methods for detecting or screening superoxide or compounds that can increase or decrease the level of superoxide in chemical and biological samples. |
| Persistent Identifier | http://hdl.handle.net/10722/221225 |
| DC Field | Value | Language |
|---|---|---|
| dc.date.accessioned | 2015-11-05T03:51:30Z | - |
| dc.date.available | 2015-11-05T03:51:30Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | US Published patent application US 20150219676. Washington, DC: US Patent and Trademark Office (USPTO), 2015 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/221225 | - |
| dc.description.abstract | The invention provides fluorogenic compounds and probes that can be used as reagents for measuring, detecting and/or screening superoxide. The fluorogenic compounds of the invention can produce fluorescence colors, such as green, yellow, red, or far-red. The invention further provides fluorogenic compounds for selectively staining superoxide in the mitochondria of living cells. The invention also provides methods that can be used to measure, directly or indirectly, the presence and/or amount of superoxide in chemical samples and biological samples such as cells and tissues in living organisms, and a high-throughput screening methods for detecting or screening superoxide or compounds that can increase or decrease the level of superoxide in chemical and biological samples. | - |
| dc.title | BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL | - |
| dc.type | Patent | - |
| dc.identifier.authority | YANG DAN=rp00825 | - |
| dc.description.nature | published_or_final_version | - |
| dc.contributor.inventor | YANG DAN | - |
| dc.contributor.inventor | WONG NAI-KEI | - |
| dc.contributor.inventor | HU JUN | - |
| patents.identifier.application | US 12/4597408 | - |
| patents.description.assignee | YANG DAN [CN]; WONG NAI-KEI [CN]; HU JUN [CN] | - |
| patents.description.country | United States of America | - |
| patents.date.publication | 2015-08-06 | - |
| patents.identifier.hkutechid | Chm-2013-00491-1 | - |
| patents.date.application | 2015-01-15 | - |
| patents.date.priority | 2015-01-15 US 12/4597408 | - |
| patents.date.priority | 2014-01-31 US 12/1934335P | - |
| patents.description.cc | us | - |
| patents.identifier.publication | US 20150219676 | - |
| patents.relation.family | WO 2015113455 (A1) 2015-08-06 | - |
| patents.description.kind | A1 | - |