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Article: Hirschsprung's Disease: A Viral Etiology?

TitleHirschsprung's Disease: A Viral Etiology?
Authors
Tam, PKHQuint, WGVVan Velzen, D
KeywordsCongenital intestinal aganglionosis
Cytomegalovirus
Hirschsprung's disease
Polymerase chain reaction
Issue Date1992
Citation
Pediatric Pathology, 1992, v. 12 n. 6, p. 807-810 How to Cite?
DOI: http://dx.doi.org/10.3109/15513819209024237
AbstractThis Study Investigates The Hypothesis That Hirschsprung's Disease (Hd), Congenital Rectal Aganglionosis, May Be Etiologically Linked To Antenatal Cytomegalovirus (Cmv) Infection. Bowel Specimens From 72 Hd Patients, 144 Control I Infants (Hirschsprung-Like Symptoms, Normal Histology), And 36 Control Ii Infants (Deaths From Nongastrointestinal Causes) Were Analyzed For Cmv Genomes By Polymerase Chain Reaction. Positive Results Were Obtained In 6 Hd Patients (8.8%) And None Of The Controls. Our Findings Suggest That Antenatal Cmv Infection, A Potentially Preventable Condition, May Be One Of The Etiological Factors In Hd.
Persistent Identifierhttp://hdl.handle.net/10722/220796
ISSN
0277-0938
ISI Accession Number ID
WOS:A1992JY61500004

 

DC FieldValueLanguage
dc.contributor.authorTam, PKHen_US
dc.contributor.authorQuint, WGVen_US
dc.contributor.authorVan Velzen, Den_US
dc.date.accessioned2015-10-19T03:49:59Z-
dc.date.available2015-10-19T03:49:59Z-
dc.date.issued1992-
dc.identifier.citationPediatric Pathology, 1992, v. 12 n. 6, p. 807-810en_US
dc.identifier.issn0277-0938-
dc.identifier.urihttp://hdl.handle.net/10722/220796-
dc.description.abstractThis Study Investigates The Hypothesis That Hirschsprung's Disease (Hd), Congenital Rectal Aganglionosis, May Be Etiologically Linked To Antenatal Cytomegalovirus (Cmv) Infection. Bowel Specimens From 72 Hd Patients, 144 Control I Infants (Hirschsprung-Like Symptoms, Normal Histology), And 36 Control Ii Infants (Deaths From Nongastrointestinal Causes) Were Analyzed For Cmv Genomes By Polymerase Chain Reaction. Positive Results Were Obtained In 6 Hd Patients (8.8%) And None Of The Controls. Our Findings Suggest That Antenatal Cmv Infection, A Potentially Preventable Condition, May Be One Of The Etiological Factors In Hd.en_US
dc.languageengen_US
dc.relation.ispartofPediatric Pathologyen_US
dc.subjectCongenital intestinal aganglionosis-
dc.subjectCytomegalovirus-
dc.subjectHirschsprung's disease-
dc.subjectPolymerase chain reaction-
dc.titleHirschsprung's Disease: A Viral Etiology?en_US
dc.typeArticleen_US
dc.identifier.emailTam, PKH:paultam@hkucc.hku.hk-
dc.identifier.authorityTam, PKH=rp00060-
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.3109/15513819209024237-
dc.identifier.pmid1333073-
dc.identifier.scopuseid_2-s2.0-0026442899-
dc.identifier.volume12-
dc.identifier.issue6-
dc.identifier.spage807-
dc.identifier.epage810-
dc.identifier.isiWOS:A1992JY61500004-
dc.identifier.issnl0277-0938-

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