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Article: Effect of Lycium barbarum (Wolfberry) on Alleviating Axonal Degeneration After Partial Optic Nerve Transection

TitleEffect of Lycium barbarum (Wolfberry) on Alleviating Axonal Degeneration After Partial Optic Nerve Transection
Authors
KeywordsLycium barbarum
Macrophage
Optic nerve (ON)
Partial transection
Secondary degeneration
Issue Date2015
PublisherCognizant Communication Corp. The Journal's web site is located at https://www.cognizantcommunication.com/journal-titles/cell-transplantation
Citation
Cell Transplantation, 2015, v. 24 n. 3, p. 403-417 How to Cite?
AbstractOur previous results showed that the polysaccharides extracted from Lycium barbarum (LBP) could delay secondary degeration of retinal ganglion cell bodies and improve the function of the retinas after partial opticnerve transection (PONT). Although the common degeneration mechanisms were believed to be shared by both neuronal bodies and axons, recently published data from slow Wallerian degeneration mutant (Wld)mice supported the divergence in the mechanisms of them. Therefore, we want to determine if LBP could also delay the degeneration of axons after PONT. Microglia/macrophages were thought to be a source of reactive oxygen species after central nervous system (CNS) injury.
Persistent Identifierhttp://hdl.handle.net/10722/216087
ISSN
2023 Impact Factor: 3.2
2023 SCImago Journal Rankings: 0.701
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, HY-
dc.contributor.authorRuan, YW-
dc.contributor.authorKau, PWF-
dc.contributor.authorChiu, K-
dc.contributor.authorChang, RCC-
dc.contributor.authorChan, HHL-
dc.contributor.authorSo, KF-
dc.date.accessioned2015-08-21T13:53:42Z-
dc.date.available2015-08-21T13:53:42Z-
dc.date.issued2015-
dc.identifier.citationCell Transplantation, 2015, v. 24 n. 3, p. 403-417-
dc.identifier.issn0963-6897-
dc.identifier.urihttp://hdl.handle.net/10722/216087-
dc.description.abstractOur previous results showed that the polysaccharides extracted from Lycium barbarum (LBP) could delay secondary degeration of retinal ganglion cell bodies and improve the function of the retinas after partial opticnerve transection (PONT). Although the common degeneration mechanisms were believed to be shared by both neuronal bodies and axons, recently published data from slow Wallerian degeneration mutant (Wld)mice supported the divergence in the mechanisms of them. Therefore, we want to determine if LBP could also delay the degeneration of axons after PONT. Microglia/macrophages were thought to be a source of reactive oxygen species after central nervous system (CNS) injury.-
dc.languageeng-
dc.publisherCognizant Communication Corp. The Journal's web site is located at https://www.cognizantcommunication.com/journal-titles/cell-transplantation-
dc.relation.ispartofCell Transplantation-
dc.rightsCell Transplantation. Copyright © Cognizant Communication Corp.-
dc.subjectLycium barbarum-
dc.subjectMacrophage-
dc.subjectOptic nerve (ON)-
dc.subjectPartial transection-
dc.subjectSecondary degeneration-
dc.titleEffect of Lycium barbarum (Wolfberry) on Alleviating Axonal Degeneration After Partial Optic Nerve Transection-
dc.typeArticle-
dc.identifier.emailLi, HY: lhy2012@hku.hk-
dc.identifier.emailKau, PWF: kwflui@HKUCC.hku.hk-
dc.identifier.emailChiu, K: datwai@hku.hk-
dc.identifier.emailChang, RCC: rccchang@hku.hk-
dc.identifier.emailSo, KF: hrmaskf@hku.hk-
dc.identifier.authorityChiu, K=rp01973-
dc.identifier.authorityChang, RCC=rp00470-
dc.identifier.authoritySo, KF=rp00329-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3727/096368915X686896-
dc.identifier.pmid25622224-
dc.identifier.scopuseid_2-s2.0-84927126359-
dc.identifier.hkuros247386-
dc.identifier.hkuros248462-
dc.identifier.volume24-
dc.identifier.issue3-
dc.identifier.spage403-
dc.identifier.epage417-
dc.identifier.isiWOS:000352754400009-
dc.publisher.placeUnited States-
dc.identifier.issnl0963-6897-

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