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- Publisher Website: 10.1039/C4NP00080C
- Scopus: eid_2-s2.0-84964282316
- PMID: 25347695
- WOS: WOS:000349031400004
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Article: Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview
Title | Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview |
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Authors | |
Issue Date | 2015 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/npr |
Citation | Natural Product Reports, 2015, v. 32, p. 256-272 How to Cite? |
Abstract | Cancer is one of the leading causes of death worldwide. Ginseng, a key ingredient in traditional Chinese medicine, shows great promise as a new treatment option. As listed by the U.S. National Institutes of Health as a complementary and alternative medicine, its anti-cancer functions are being increasingly recognized. This review covers the mechanisms of action of ginsenosides and their metabolites, which can modulate signaling pathways associated with inflammation, oxidative stress, angiogenesis, metastasis, and stem/progenitor-like properties of cancer cells. The emerging use of structurally modified ginsenosides and recent clinical studies on the use of ginseng either alone or in combination with other herbs or Western medicines which are exploited as novel therapeutic strategies will also be explored. |
Persistent Identifier | http://hdl.handle.net/10722/215138 |
ISSN | 2023 Impact Factor: 10.2 2023 SCImago Journal Rankings: 2.297 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Wong, AST | - |
dc.contributor.author | Che, CM | - |
dc.contributor.author | Leung, KW | - |
dc.date.accessioned | 2015-08-21T13:15:32Z | - |
dc.date.available | 2015-08-21T13:15:32Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Natural Product Reports, 2015, v. 32, p. 256-272 | - |
dc.identifier.issn | 0265-0568 | - |
dc.identifier.uri | http://hdl.handle.net/10722/215138 | - |
dc.description.abstract | Cancer is one of the leading causes of death worldwide. Ginseng, a key ingredient in traditional Chinese medicine, shows great promise as a new treatment option. As listed by the U.S. National Institutes of Health as a complementary and alternative medicine, its anti-cancer functions are being increasingly recognized. This review covers the mechanisms of action of ginsenosides and their metabolites, which can modulate signaling pathways associated with inflammation, oxidative stress, angiogenesis, metastasis, and stem/progenitor-like properties of cancer cells. The emerging use of structurally modified ginsenosides and recent clinical studies on the use of ginseng either alone or in combination with other herbs or Western medicines which are exploited as novel therapeutic strategies will also be explored. | - |
dc.language | eng | - |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/npr | - |
dc.relation.ispartof | Natural Product Reports | - |
dc.title | Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview | - |
dc.type | Article | - |
dc.identifier.email | Wong, AST: awong1@hku.hk | - |
dc.identifier.email | Che, CM: cmche@hku.hk | - |
dc.identifier.authority | Wong, AST=rp00805 | - |
dc.identifier.authority | Che, CM=rp00670 | - |
dc.identifier.authority | Leung, KW=rp01674 | - |
dc.identifier.doi | 10.1039/C4NP00080C | - |
dc.identifier.pmid | 25347695 | - |
dc.identifier.scopus | eid_2-s2.0-84964282316 | - |
dc.identifier.hkuros | 246903 | - |
dc.identifier.volume | 32 | - |
dc.identifier.spage | 256 | - |
dc.identifier.epage | 272 | - |
dc.identifier.eissn | 1460-4752 | - |
dc.identifier.isi | WOS:000349031400004 | - |
dc.publisher.place | Cambridge, UK | - |
dc.identifier.issnl | 0265-0568 | - |