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Conference Paper: Measuring the physical properties of the lymphoma cells using atomic force microscopy

TitleMeasuring the physical properties of the lymphoma cells using atomic force microscopy
Authors
Li, MiLiu, LianqingXi, NingWang, YuechaoDong, ZailiLi, GuangyongXiao, XiubinZhang, Weijing
Issue Date2010
Citation
2010 IEEE Nanotechnology Materials and Devices Conference, NMDC2010, 2010, p. 310-314 How to Cite?
DOI: http://dx.doi.org/10.1109/NMDC.2010.5652223
AbstractIlluminating the underlying mechanism of drug action at single-cell and single-molecule levels is of great significance for the personalized treatment of diseases. In this paper, with the use of the atomic force microscopy (AFM), the mechanical property of the lymphoma cells was quantitatively measured and the CD20-Rituximab binding force was measured on the surface of the lymphoma cells by linking the Rituximab molecules onto the AFM tip. The results lay the foundation for the further study of the molecular mechanism of Rituximab anti-cancer effect. © 2010 IEEE.
Persistent Identifierhttp://hdl.handle.net/10722/213136
ISI Accession Number ID
WOS:000279572200080

 

DC FieldValueLanguage
dc.contributor.authorLi, Mi-
dc.contributor.authorLiu, Lianqing-
dc.contributor.authorXi, Ning-
dc.contributor.authorWang, Yuechao-
dc.contributor.authorDong, Zaili-
dc.contributor.authorLi, Guangyong-
dc.contributor.authorXiao, Xiubin-
dc.contributor.authorZhang, Weijing-
dc.date.accessioned2015-07-28T04:06:15Z-
dc.date.available2015-07-28T04:06:15Z-
dc.date.issued2010-
dc.identifier.citation2010 IEEE Nanotechnology Materials and Devices Conference, NMDC2010, 2010, p. 310-314-
dc.identifier.urihttp://hdl.handle.net/10722/213136-
dc.description.abstractIlluminating the underlying mechanism of drug action at single-cell and single-molecule levels is of great significance for the personalized treatment of diseases. In this paper, with the use of the atomic force microscopy (AFM), the mechanical property of the lymphoma cells was quantitatively measured and the CD20-Rituximab binding force was measured on the surface of the lymphoma cells by linking the Rituximab molecules onto the AFM tip. The results lay the foundation for the further study of the molecular mechanism of Rituximab anti-cancer effect. © 2010 IEEE.-
dc.languageeng-
dc.relation.ispartof2010 IEEE Nanotechnology Materials and Devices Conference, NMDC2010-
dc.titleMeasuring the physical properties of the lymphoma cells using atomic force microscopy-
dc.typeConference_Paper-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1109/NMDC.2010.5652223-
dc.identifier.scopuseid_2-s2.0-78651476870-
dc.identifier.spage310-
dc.identifier.epage314-
dc.identifier.isiWOS:000279572200080-

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