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- Publisher Website: 10.1109/ROBIO.2009.4912975
- Scopus: eid_2-s2.0-70349166767
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Conference Paper: In-situ mechanical property evaluation of different stage drosophila embryos with a minimally invasive microforce sensing tool
Title | In-situ mechanical property evaluation of different stage drosophila embryos with a minimally invasive microforce sensing tool |
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Authors | |
Keywords | Young's modulus Embryogenic stages Fruit fly drosophila embryo Mechanical impedance Microforce Microinjection Stiffness |
Issue Date | 2008 |
Citation | 2008 IEEE International Conference on Robotics and Biomimetics, ROBIO 2008, 2008, p. 31-36 How to Cite? |
Abstract | The fruit fly Drosophila is one of the most important model organisms in genetics and developmental biology research. To better understand the biomechanical properties involved in Drosophila embryo research, this work presents a mechanical characterization of living Drosophila embryos through the stages of embryogenesis. Measurements of the mechanical forces of Drosophila embryos are implemented using a novel, in-situ, and minimally invasive force sensing tool with a resolution in the range of μN. The measurements offer an essential understanding of penetration force profiles during the microinjection of Drosophila embryos. Sequentially quantitative evaluation and analysis of the mechanical properties, such as Young's modulus, stiffness, and mechanical impedance of living Drosophila embryos are performed by extracting the force measurements throughout the stages of embryogenesis. The evaluation provides a critical step toward better understanding of the biomechanical properties of Drosophila embryos during embryogenesis, and could contribute to more efficient and significant genetic and embryonic development research on Drosophila. © 2008 IEEE. |
Persistent Identifier | http://hdl.handle.net/10722/213060 |
DC Field | Value | Language |
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dc.contributor.author | Shen, Yantao | - |
dc.contributor.author | Xi, Ning | - |
dc.contributor.author | Zhang, Rui | - |
dc.date.accessioned | 2015-07-28T04:06:00Z | - |
dc.date.available | 2015-07-28T04:06:00Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | 2008 IEEE International Conference on Robotics and Biomimetics, ROBIO 2008, 2008, p. 31-36 | - |
dc.identifier.uri | http://hdl.handle.net/10722/213060 | - |
dc.description.abstract | The fruit fly Drosophila is one of the most important model organisms in genetics and developmental biology research. To better understand the biomechanical properties involved in Drosophila embryo research, this work presents a mechanical characterization of living Drosophila embryos through the stages of embryogenesis. Measurements of the mechanical forces of Drosophila embryos are implemented using a novel, in-situ, and minimally invasive force sensing tool with a resolution in the range of μN. The measurements offer an essential understanding of penetration force profiles during the microinjection of Drosophila embryos. Sequentially quantitative evaluation and analysis of the mechanical properties, such as Young's modulus, stiffness, and mechanical impedance of living Drosophila embryos are performed by extracting the force measurements throughout the stages of embryogenesis. The evaluation provides a critical step toward better understanding of the biomechanical properties of Drosophila embryos during embryogenesis, and could contribute to more efficient and significant genetic and embryonic development research on Drosophila. © 2008 IEEE. | - |
dc.language | eng | - |
dc.relation.ispartof | 2008 IEEE International Conference on Robotics and Biomimetics, ROBIO 2008 | - |
dc.subject | Young's modulus | - |
dc.subject | Embryogenic stages | - |
dc.subject | Fruit fly drosophila embryo | - |
dc.subject | Mechanical impedance | - |
dc.subject | Microforce | - |
dc.subject | Microinjection | - |
dc.subject | Stiffness | - |
dc.title | In-situ mechanical property evaluation of different stage drosophila embryos with a minimally invasive microforce sensing tool | - |
dc.type | Conference_Paper | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1109/ROBIO.2009.4912975 | - |
dc.identifier.scopus | eid_2-s2.0-70349166767 | - |
dc.identifier.spage | 31 | - |
dc.identifier.epage | 36 | - |